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A Phase 2 Basket Trial of Ulixertinib (BVD-523) in Combination with Hydroxychloroquine in Patients with Advanced Gastrointestinal Malignancies Harboring MAPK Pathway Mutations.
Protocol: 052216Principal Investigator:
- Sanjay Goel (Rutgers University)
Applicable Disease Sites: Anus
Small Intestine
Colon
Esophagus
Stomach
Rectum
Other Digestive Organ
Pancreas -
A Phase 2/3 Randomized, Controlled Study of CTX-009 in Combination with Paclitaxel versus Paclitaxel Alone in Adult Patients with Unresectable Advanced, Metastatic or Recurrent Biliary Tract Cancers who have received One Prior Systemic Chemotherapy Regimen.
Protocol: 072214Principal Investigator:
- Howard Hochster M.D (Rutgers University)
Applicable Disease Sites: Other Digestive Organ -
A Phase 2 Study of CTX-009 in Adult Patients with Metastatic Colorectal Cancer who have received Two or Three Prior Systemic Chemotherapy Regimens.
Protocol: 072301Principal Investigator:
- Patrick Boland (Rutgers University)
Applicable Disease Sites: Colon -
A Phase 1/1b Study of ASP2138 in Participants with Metastatic or Locally Advanced Unresectable Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma or Metastatic Pancreatic Adenocarcinoma Whose Tumors Have Claudin (CLDN) 18.2
Expression
Protocol: 072305Principal Investigator:
- Howard Hochster M.D (Rutgers University)
Applicable Disease Sites: Pancreas -
Optimal Perioperative Therapy For Incidental Gallbladder Cancer (OPT-IN): A Randomized Phase II/III Trial.
Protocol: 072306Principal Investigator:
- Brett Ecker MD (Rutgers Cancer Institute of New Jersey-University Hospital)
Applicable Disease Sites: Other Digestive Organ -
A Phase II, open-label, multi-cohort, multicenter study in patients with unresectable HEPATOCELLULAR CARCINOMA and CHILDPUGH B7 and B8 Cirrhosis
Protocol: 072309Principal Investigator:
- Howard Hochster M.D (Rutgers University)
Applicable Disease Sites: Liver