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Guo Laboratory - Select Publications

  1. Guo JY and White E. Autophagy, Metabolism, and Cancer. Cold Spring Harbor Symposia on Quantitative Biology, 2017; Feb 16. pii: 030981. doi:10.1101/sqb.2016.81.030981. PubMed PMID: 28209717.
  2. Guo JY#*, Teng X*, Laddha SV, Ma S, Van Nostrand SC, Yang Y, Khor S, Chan CS, Rabinowitz JD, White E#. Autophagy provides metabolic substrates to maintain energy charge and nucleotide pools in Ras-driven lung cancer cells. Genes & development. 2016;30(15):1704-17. doi: 10.1101/gad.283416.116. PubMed PMID: 27516533.
  3. Karsli-Uzunbas G, Guo JY, Price S, Teng X, Laddha SV, Khor S, Kalaany NY, Jacks T, Chan CS, Rabinowitz JD, White E. Autophagy is required for glucose homeostasis and lung tumor maintenance. Cancer discovery. 2014;4(8):914-27. doi: 10.1158/2159-8290.CD-14-0363. PubMed PMID: 24875857; PubMed Central PMCID: PMC4125614.
  4. Guo JY, Xia B, White E. Autophagy-mediated tumor promotion. Cell. 2013;155(6):1216-9. doi: 10.1016/j.cell.2013.11.019. PubMed PMID: 24315093.
  5. Guo JY, White E. Autophagy is required for mitochondrial function, lipid metabolism, growth and fate of KRAS (G12D) -driven lung tumors. Autophagy. 2013;9(10). PubMed PMID: 23959381.
  6. Guo JY, Karsli-Uzunbas G, Mathew R, Aisner SC, Kamphorst JJ, Strohecker AM, Chen G, Price S, Lu W, Teng X, Snyder E, Santanam U, Dipaola RS, Jacks T, Rabinowitz JD, White E. Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis. Genes & development. 2013;27(13):1447-61. doi: 10.1101/gad.219642.113. PubMed PMID: 23824538; PubMed Central PMCID: PMC3713426.
  7. Guo JY*, Chen HY*, Mathew R*, Fan J*, Strohecker AM, Karsli-Uzunbas G, Kamphorst JJ, Chen G, Lemons JM, Karantza V, Coller HA, Dipaola RS, Gelinas C, Rabinowitz JD, White E. Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis. Genes & development. 2011;25(5):460-70. doi: 10.1101/gad.2016311. PubMed PMID: 21317241; PubMed Central PMCID: PMC3049287.
  8. White E, Karp C, Strohecker AM, Guo Y, Mathew R. Role of autophagy in suppression of inflammation and cancer. Current opinion in cell biology. 2010;22(2):212-7. doi: 10.1016/j.ceb.2009.12.008. PubMed PMID: 20056400; PubMed Central PMCID: PMC2857707.

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