- Zheng Y#, Chen Z, Han Y, Han L, Zou X, Zhou B, Hu R, Hao J, Bai S, Xiao H, Li WV, Bueker A, Ma Y, Xie G, Yang J, Chen S, Li H#, Cao J#, Shen L#. Immune suppressive landscape in the human esophageal squamous cell carcinoma microenvironment. Nat Commun. 2020;11(1):6268. Epub 2020/12/10. doi: 10.1038/s41467-020-20019-0. PubMed PMID: 33293583; PMCID: PMC7722722. (#correspondence)
- Poillet-Perez L, Sharp DW, Yang Y, Laddha SV, Ibrahim M, Bommareddy PK, Hu ZS, Vieth J, Haas M, Bosenberg MW, Rabinowitz JD, Cao J, Guan J-L, Ganesan S, Chan CS, Mehnert JM, Lattime EC, White E. Autophagy promotes growth of tumors with high mutational burden by inhibiting a T-cell immune response. Nature Cancer. 2020;1(9):923-34. doi: 10.1038/s43018-020-00110-7.
- Cao J, Yan Q. Cancer Epigenetics, Tumor Immunity, and Immunotherapy. Trends Cancer. 2020;6(7):580-92. Epub 2020/07/02. doi: 10.1016/j.trecan.2020.02.003. PubMed PMID: 32610068; PMCID: PMC7330177.
- Cai WL, Greer CB, Chen JF, Arnal-Estape A, Cao J, Yan Q, Nguyen DX. Specific chromatin landscapes and transcription factors couple breast cancer subtype with metastatic relapse to lung or brain. BMC Med Genomics. 2020;13(1):33. Epub 2020/03/08. doi: 10.1186/s12920-020-0695-0. PubMed PMID: 32143622; PMCID: PMC7060551.
- Gale M, Li Y, Cao J, Liu ZZ, Holmbeck MA, Zhang M, Lang SM, Wu L, Do Carmo M, Gupta S, Aoshima K, DiGiovanna MP, Stern DF, Rimm DL, Shadel GS, Chen X, Yan Q. Acquired Resistance to HER2-Targeted Therapies Creates Vulnerability to ATP Synthase Inhibition. Cancer Res. 2020;80(3):524-35. Epub 2019/11/07. doi: 10.1158/0008-5472.CAN-18-3985. PubMed PMID: 31690671; PMCID: PMC7002225.
- Wali VB, Patwardhan GA, Pelekanou V, Karn T, Cao J, Ocana A, Yan Q, Nelson B, Hatzis C, Pusztai L. Identification and Validation of a Novel Biologics Target in Triple Negative Breast Cancer. Sci Rep. 2019;9(1):14934. Epub 2019/10/19. doi: 10.1038/s41598-019-51453-w. PubMed PMID: 31624295; PMCID: PMC6797726.
- Chen X, Kost J, Sulovari A, Wong N, Liang WS, Cao J#, Li D#. A virome-wide clonal integration analysis platform for discovering cancer viral etiology. Genome Res. 2019;29(5):819-30. Epub 2019/03/16. doi: 10.1101/gr.242529.118. PubMed PMID: 30872350; PMCID: PMC6499315. (#correspondence)
- Halaban R, Bacchiocchi A, Straub R, Cao J, Sznol M, Narayan D, Allam A, Krauthammer M, Mansour TS. A novel anti-melanoma SRC-family kinase inhibitor. Oncotarget. 2019;10(23):2237-51. Epub 2019/05/02. doi: 10.18632/oncotarget.26787. PubMed PMID: 31040916; PMCID: PMC6481345.
- Cao J#, Xiao Q, Yan Q#. The multiplexed CRISPR targeting platforms. Drug Discov Today Technol. 2018;28:53-61. Epub 2018/09/13. doi: 10.1016/j.ddtec.2018.01.001. PubMed PMID: 30205881; PMCID: PMC6699180. (#correspondence)
- Wu L*, Cao J*, Cai WL, Lang SM, Horton JR, Jansen DJ, Liu ZZ, Chen JF, Zhang M, Mott BT, Pohida K, Rai G, Kales SC, Henderson MJ, Hu X, Jadhav A, Maloney DJ, Simeonov A, Zhu S, Iwasaki A, Hall MD, Cheng X, Shadel GS, Yan Q. KDM5 histone demethylases repress immune response via suppression of STING. PLoS Biol. 2018;16(8):e2006134. Epub 2018/08/07. doi: 10.1371/journal.pbio.2006134. PubMed PMID: 30080846; PMCID: PMC6095604. (*equal contribution)
- Cao J#, Li D#. Searching for human oncoviruses: Histories, challenges, and opportunities. J Cell Biochem. 2018;119(6):4897-906. Epub 2018/01/30. doi: 10.1002/jcb.26717. PubMed PMID: 29377246. (#correspondence)
- Blair LP, Liu Z, Labitigan RL, Wu L, Zheng D, Xia Z, Pearson EL, Nazeer FI, Cao J, Lang SM, Rines RJ, Mackintosh SG, Moore CL, Li W, Tian B, Tackett AJ, Yan Q. KDM5 lysine demethylases are involved in maintenance of 3'UTR length. Sci Adv. 2016;2(11):e1501662. Epub 2017/02/01. doi: 10.1126/sciadv.1501662. PubMed PMID: 28138513; PMCID: PMC5262454.
- Cao J, Wu L, Zhang SM, Lu M, Cheung WK, Cai W, Gale M, Xu Q, Yan Q. An easy and efficient inducible CRISPR/Cas9 platform with improved specificity for multiple gene targeting. Nucleic Acids Res. 2016;44(19):e149. Epub 2016/11/02. doi: 10.1093/nar/gkw660. PubMed PMID: 27458201; PMCID: PMC5100567.
- Gale M, Sayegh J, Cao J, Norcia M, Gareiss P, Hoyer D, Merkel JS, Yan Q. Screen-identified selective inhibitor of lysine demethylase 5A blocks cancer cell growth and drug resistance. Oncotarget. 2016;7(26):39931-44. Epub 2016/10/26. doi: 10.18632/oncotarget.9539. PubMed PMID: 27224921; PMCID: PMC5129982.
- Zou MR, Cao J, Liu Z, Huh SJ, Polyak K, Yan Q. Histone demethylase jumonji AT-rich interactive domain 1B (JARID1B) controls mammary gland development by regulating key developmental and lineage specification genes. J Biol Chem. 2014;289(25):17620-33. Epub 2014/05/08. doi: 10.1074/jbc.M114.570853. PubMed PMID: 24802759; PMCID: PMC4067197.
- Cao J, Liu Z, Cheung WK, Zhao M, Chen SY, Chan SW, Booth CJ, Nguyen DX, Yan Q. Histone demethylase RBP2 is critical for breast cancer progression and metastasis. Cell Rep. 2014;6(5):868-77. Epub 2014/03/04. doi: 10.1016/j.celrep.2014.02.004. PubMed PMID: 24582965; PMCID: PMC4014129.
- Cao J, Liu X, Han S, Zhang CK, Liu Z, Li D. Association of the HTR2A gene with alcohol and heroin abuse. Hum Genet. 2014;133(3):357-65. Epub 2013/11/02. doi: 10.1007/s00439-013-1388-y. PubMed PMID: 24178752; PMCID: PMC4085799.
- Cao J, Hudziak JJ, Li D. Multi-cultural association of the serotonin transporter gene (SLC6A4) with substance use disorder. Neuropsychopharmacology. 2013;38(9):1737-47. Epub 2013/03/23. doi: 10.1038/npp.2013.73. PubMed PMID: 23518607; PMCID: PMC3717550.
- Cao J, Yan Q. Histone demethylases set the stage for cancer metastasis. Sci Signal. 2013;6(273):pe15, 1-2. Epub 2013/05/02. doi: 10.1126/scisignal.2004188. PubMed PMID: 23633674.
- Sayegh J, Cao J, Zou MR, Morales A, Blair LP, Norcia M, Hoyer D, Tackett AJ, Merkel JS, Yan Q. Identification of small molecule inhibitors of Jumonji AT-rich interactive domain 1B (JARID1B) histone demethylase by a sensitive high throughput screen. J Biol Chem. 2013;288(13):9408-17. Epub 2013/02/15. doi: 10.1074/jbc.M112.419861. PubMed PMID: 23408432; PMCID: PMC3611010.
- Cao J, LaRocque E, Li D. Associations of the 5-hydroxytryptamine (serotonin) receptor 1B gene (HTR1B) with alcohol, cocaine, and heroin abuse. Am J Med Genet B Neuropsychiatr Genet. 2013;162B(2):169-76. Epub 2013/01/22. doi: 10.1002/ajmg.b.32128. PubMed PMID: 23335468; PMCID: PMC4089973.
- Cao J#, Yan Q#. Histone ubiquitination and deubiquitination in transcription, DNA damage response, and cancer. Front Oncol. 2012;2:26. Epub 2012/06/01. doi: 10.3389/fonc.2012.00026. PubMed PMID: 22649782; PMCID: PMC3355875. (#correspondence)
- Lin W*, Cao J*, Liu J, Beshiri ML, Fujiwara Y, Francis J, Cherniack AD, Geisen C, Blair LP, Zou MR, Shen X, Kawamori D, Liu Z, Grisanzio C, Watanabe H, Minamishima YA, Zhang Q, Kulkarni RN, Signoretti S, Rodig SJ, Bronson RT, Orkin SH, Tuck DP, Benevolenskaya EV, Meyerson M, Kaelin WG, Jr., Yan Q. Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1. Proc Natl Acad Sci U S A. 2011;108(33):13379-86. Epub 2011/07/27. doi: 10.1073/pnas.1110104108. PubMed PMID: 21788502; PMCID: PMC3158206. (*equal contribution)
- Blair LP, Cao J, Zou MR, Sayegh J, Yan Q. Epigenetic Regulation by Lysine Demethylase 5 (KDM5) Enzymes in Cancer. Cancers (Basel). 2011;3(1):1383-404. Epub 2011/05/06. doi: 10.3390/cancers3011383. PubMed PMID: 21544224; PMCID: PMC3085456.
- Ge L, Wang J, Qi W, Miao HH, Cao J, Qu YX, Li BL, Song BL. The cholesterol absorption inhibitor ezetimibe acts by blocking the sterol-induced internalization of NPC1L1. Cell Metab. 2008;7(6):508-19. Epub 2008/06/05. doi: 10.1016/j.cmet.2008.04.001. PubMed PMID: 18522832.
- Cao J, Wang J, Qi W, Miao HH, Wang J, Ge L, DeBose-Boyd RA, Tang JJ, Li BL, Song BL. Ufd1 is a cofactor of gp78 and plays a key role in cholesterol metabolism by regulating the stability of HMG-CoA reductase. Cell Metab. 2007;6(2):115-28. Epub 2007/08/08. doi: 10.1016/j.cmet.2007.07.002. PubMed PMID: 17681147.
- Yang Y, Cao J, Huang L, Fang HY, Sheng HZ. Regulated expression of TATA-binding protein-related factor 3 (TRF3) during early embryogenesis. Cell Res. 2006;16(7):610-21. Epub 2006/05/25. doi: 10.1038/sj.cr.7310064. PubMed PMID: 16721357.
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