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Selected Publications

da Silva-Diz V, Herranz D. Forever young: Sphk2 in HSCs, when less is more. Blood. 2022 Oct 13;140(15):1658-1660. PMID:36227746.

Ghaddar B, Biswas A, Harris C, Omary MB, Carpizo DR, Blaser MJ, De S. Tumor microbiome links cellular programs and immunity in pancreatic cancer. Cancer Cell. 2022 Oct 10;40(10):1240-1253.e5. PMID:36220074.

Deshpande M, Paniza T, Jalloul N, Nanjangud G, Twarowski J, Koren A, Zaninovic N, Zhan Q, Chadalavada K, Malkova A, Khiabanian H, Madireddy A, Rosenwaks Z, Gerhardt J. Error-prone repair of stalled replication forks drives mutagenesis and loss of heterozygosity in haploinsufficient BRCA1 cells. Mol Cell. 2022 Oct 20;82(20):3781-3793.e7. PMID:36099913.

Biswas A, Ghaddar B, Riedlinger G, De S. Inference on spatial heterogeneity in tumor microenvironment using spatial transcriptomics data. Comput Syst Oncol. 2022 Sep;2(3):e21043. PMID:36035873.

Bjørklund SS, Aure MR, Häkkinen J, Vallon-Christersson J, Kumar S, Evensen KB, Fleischer T, Tost J; OSBREAC, Sahlberg KK, Mathelier A, Bhanot G, Ganesan S, Tekpli X, Kristensen VN. Subtype and cell type specific expression of lncRNAs provide insight into breast cancer. Commun Biol. 2022 Aug 18;5(1):834. PMID:35982125.

Ganesan S. Breaking satellite silence: human satellite II RNA expression in ovarian cancer. J Clin Invest. 2022 Aug 15;132(16):e161981. PMID:35968784.

Zingg D, Bhin J, Yemelyanenko J, Kas SM, Rolfs F, Lutz C, Lee JK, Klarenbeek S, Silverman IM, Annunziato S, Chan CS, Piersma SR, Eijkman T, Badoux M, Gogola E, Siteur B, Sprengers J, de Klein B, de Goeij-de Haas RR, Riedlinger GM, Ke H, Madison R, Drenth AP, van der Burg E, Schut E, Henneman L, van Miltenburg MH, Proost N, Zhen H, Wientjens E, de Bruijn R, de Ruiter JR, Boon U, de Korte- Grimmerink R, van Gerwen B, Féliz L, Abou-Alfa GK, Ross JS, van de Ven M, Rottenberg S, Cuppen E, Chessex AV, Ali SM, Burn TC, Jimenez CR, Ganesan S, Wessels LFA, Jonkers J. Truncated FGFR2 is a clinically actionable oncogene in multiple cancers. Nature. 2022 Aug;608(7923):609-617. PMID:35948633.

Xiao Q, Zhang X, Tu L, Cao J, Hinrichs CS, Su X. Size-dependent activation of CAR-T cells. Sci Immunol. 2022 Aug 5;7(74):eabl3995. PMID:35930653.

Hu X, Biswas A, De S. KMT2C-deficient tumors have elevated APOBEC mutagenesis and genomic instability in multiple cancers. NAR Cancer. 2022 Jul 25;4(3):zcac023. PMID:35898555.

Bal E, Kumar R, Hadigol M, Holmes AB, Hilton LK, Loh JW, Dreval K, Wong JCH, Vlasevska S, Corinaldesi C, Soni RK, Basso K, Morin RD, Khiabanian H, Pasqualucci L, Dalla-Favera R. Super-enhancer hypermutation alters oncogene expression in B cell lymphoma. Nature. 2022 Jul;607(7920):808-815. PMID:0.

Shaheen MF, Tse JY, Sokol ES, Masterson M, Bansal P, Rabinowitz I, Tarleton CA, Dobroff AS, Smith TL, Bocklage TJ, Mannakee BK, Gutenkunst RN, Bischoff J, Ness SA, Riedlinger GM, Groisberg R, Pasqualini R, Ganesan S, Arap W. Genomic landscape of lymphatic malformations: a case series and response to the PI3Kα inhibitor alpelisib in an N-of-1 clinical trial. Elife. 2022 Jul 5;11:e74510. PMID:35787784.

Aita R, Aldea D, Hassan S, Hur J, Pellon-Cardenas O, Cohen E, Chen L, Shroyer N, Christakos S, Verzi MP, Fleet JC. Genomic analysis of 1,25-dihydroxyvitamin D3 action in mouse intestine reveals compartment and segment-specific gene regulatory effects. J Biol Chem. 2022 Aug;298(8):102213. PMID:35779631.

Jalloul N, Ganesan S, Garber JE, Khiabanian H. Reply to T. Ménard. JCO Precis Oncol. PMID:35709401.

Sun H, Huang B, Cao J, Yan Q, Yin M. Editorial: Epigenetic Regulation and Tumor Immunotherapy. Front Oncol. 2022 May 5;12:893157. PMID:35600405.

Baran N, Lodi A, Dhungana Y, Herbrich S, Collins M, Sweeney S, Pandey R, Skwarska A, Patel S, Tremblay M, Kuruvilla VM, Cavazos A, Kaplan M, Warmoes MO, Veiga DT, Furudate K, Rojas-Sutterin S, Haman A, Gareau Y, Marinier A, Ma H, Harutyunyan K, Daher M, Garcia LM, Al-Atrash G, Piya S, Ruvolo V, Yang W, Shanmugavelandy SS, Feng N, Gay J, Du D, Yang JJ, Hoff FW, Kaminski M, Tomczak K, Eric Davis R, Herranz D, Ferrando A, Jabbour EJ, Emilia Di Francesco M, Teachey DT, Horton TM, Kornblau S, Rezvani K, Sauvageau G, Gagea M, Andreeff M, Takahashi K, Marszalek JR, Lorenzi PL, Yu J, Tiziani S, Hoang T, Konopleva M. Inhibition of mitochondrial complex I reverses NOTCH1-driven metabolic reprogramming in T-cell acute lymphoblastic leukemia. Nat Commun. 2022 May 19;13(1):2801. PMID:35589701.

Madison RW, Hu X, Ramanan V, Xu Z, Huang RSP, Sokol ES, Frampton GM, Schrock AB, Ali SM, Ganesan S, De S. Clustered 8-Oxo-Guanine Mutations and Oncogenic Gene Fusions in Microsatellite-Unstable Colorectal Cancer. JCO Precis Oncol. 2022 May;6:e2100477. PMID:35584350.

Ghaddar B, De S. Reconstructing physical cell interaction networks from single-cell data using Neighbor-seq. Nucleic Acids Res. 2022 Aug 12;50(14):e82. PMID:35536255.

Lee S, Abed DA, Nguyen MU, Verzi MP, Hu L. Structure-activity relationships of 1,4-bis(arylsulfonamido)-benzene or naphthalene-N,N'-diacetic acids with varying C2-substituents as inhibitors of Keap1-Nrf2 protein-protein interaction. Eur J Med Chem. 2022 Jul 5;237:114380. PMID:35462166.

Schulman A, Bhanot G. Using postal change-of-address data to predict second waves in infections near pandemic epicentres. Epidemiol Infect. 2022 Mar 24;150:e120. PMID:35321775.

Panda A, Betigeri A, Ganesan S. A Gene Panel for Early Identification of Future Responders to Immune Checkpoint Blockade. Front Genet. 2022 Mar 3;13:706468. PMID:35309122.

Qureshi S, Chan N, George M, Ganesan S, Toppmeyer D, Omene C. Immune Checkpoint Inhibitors in Triple Negative Breast Cancer: The Search for the Optimal Biomarker. Biomark Insights. 2022 Feb 22;17:11772719221078774. PMID:35221668.

Chakravarty D, Johnson A, Sklar J, Lindeman NI, Moore K, Ganesan S, Lovly CM, Perlmutter J, Gray SW, Hwang J, Lieu C, André F, Azad N, Borad M, Tafe L, Messersmith H, Robson M, Meric-Bernstam F. Somatic Genomic Testing in Patients With Metastatic or Advanced Cancer: ASCO Provisional Clinical Opinion. J Clin Oncol. 2022 Apr 10;40(11):1231-1258. PMID:35175857.

Foran DJ, Durbin EB, Chen W, Sadimin E, Sharma A, Banerjee I, Kurc T, Li N, Stroup AM, Harris G, Gu A, Schymura M, Gupta R, Bremer E, Balsamo J, DiPrima T, Wang F, Abousamra S, Samaras D, Hands I, Ward K, Saltz JH. An Expandable Informatics Framework for Enhancing Central Cancer Registries with Digital Pathology Specimens, Computational Imaging Tools, and Advanced Mining Capabilities. J Pathol Inform. 2022 Jan 5;13:5. PMID:35136672.

Poillet-Perez L, Sharp DW, Yang Y, Laddha SV, Ibrahim M, Bommareddy PK, Hu ZS, Vieth J, Haas M, Bosenberg MW, Rabinowitz JD, Cao J, Guan JL, Ganesan S, Chan CS, Mehnert JM, Lattime EC, White E. Publisher Correction: Autophagy promotes growth of tumors with high mutational burden by inhibiting a T-cell immune response. Nat Cancer. 2021 Sep;2(9):994. PMID:35121870.

Minteer C, Morselli M, Meer M, Cao J, Higgins-Chen A, Lang SM, Pellegrini M, Yan Q, Levine ME. Tick tock, tick tock: Mouse culture and tissue aging captured by an epigenetic clock. Aging Cell. 2022 Feb;21(2):e13553. PMID:35104377.

Das S, Feng Q, Balasubramanian I, Lin X, Liu H, Pellón-Cardenas O, Yu S, Zhang X, Liu Y, Wei Z, Bonder EM, Verzi MP, Hsu W, Zhang L, Wang TC, Gao N. Colonic healing requires Wnt produced by epithelium as well as Tagln+ and Acta2+ stromal cells. Development. 2022 Jan 1;149(1):dev199587. PMID:34910127.

Panda A, Bhanot G, Ganesan S, Bajpai M. Gene Expression in Barrett's Esophagus Cell Lines Resemble Esophageal Squamous Cell Carcinoma Instead of Esophageal Adenocarcinoma. Cancers (Basel). 2021 Nov 27;13(23):5971. PMID:34885081.

Rajagopalan S, Singh A, Khiabanian H. Cilium Expression Score Predicts Glioma Survival. Front Genet. 2021 Nov 19;12:758391. PMID:34868236.

Jalloul N, Gomy I, Stokes S, Gusev A, Johnson BE, Lindeman NI, Macconaill L, Ganesan S, Garber JE, Khiabanian H. Germline Testing Data Validate Inferences of Mutational Status for Variants Detected From Tumor-Only Sequencing. JCO Precis Oncol. 2021 Nov 17;5:PO.21.00279. PMID:34820595.

Butner JD, Martin GV, Wang Z, Corradetti B, Ferrari M, Esnaola N, Chung C, Hong DS, Welsh JW, Hasegawa N, Mittendorf EA, Curley SA, Chen SH, Pan PY, Libutti SK, Ganesan S, Sidman RL, Pasqualini R, Arap W, Koay EJ, Cristini V. Early prediction of clinical response to checkpoint inhibitor therapy in human solid tumors through mathematical modeling. Elife. 2021 Nov 9;10:e70130. PMID:34749885.

Westphalen CB, Fine AD, André F, Ganesan S, Heinemann V, Rouleau E, Turnbull C, Garcia Palacios L, Lopez JA, Sokol ES, Mateo J. Pan-cancer Analysis of Homologous Recombination Repair-associated Gene Alterations and Genome-wide Loss-of-Heterozygosity Score. Clin Cancer Res. 2022 Apr 1;28(7):1412-1421. PMID:34740923.

De S. Signatures Beyond Oncogenic Mutations in Cell-Free DNA Sequencing for Non-Invasive, Early Detection of Cancer. Front Genet. 2021 Oct 14;12:759832. PMID:34721546.

Bonfiglio F, Bruscaggin A, Guidetti F, Terzi di Bergamo L, Faderl M, Spina V, Condoluci A, Bonomini L, Forestieri G, Koch R, Piffaretti D, Pini K, Pirosa MC, Cittone MG, Arribas A, Lucioni M, Ghilardi G, Wu W, Arcaini L, Baptista MJ, Bastidas G, Bea S, Boldorini R, Broccoli A, Buehler MM, Canzonieri V, Cascione L, Ceriani L, Cogliatti S, Corradini P, Derenzini E, Devizzi L, Dietrich S, Elia AR, Facchetti F, Gaidano G, Garcia JF, Gerber B, Ghia P, Gomes da Silva M, Gritti G, Guidetti A, Hitz F, Inghirami G, Ladetto M, Lopez-Guillermo A, Lucchini E, Maiorana A, Marasca R, Matutes E, Meignin V, Merli M, Moccia A, Mollejo M, Montalban C, Novak U, Oscier DG, Passamonti F, Piazza F, Pizzolitto S, Rambaldi A, Sabattini E, Salles G, Santambrogio E, Scarfò L, Stathis A, Stüssi G, Geyer JT, Tapia G, Tarella C, Thieblemont C, Tousseyn T, Tucci A, Vanini G, Visco C, Vitolo U, Walewska R, Zaja F, Zenz T, Zinzani PL, Khiabanian H, Calcinotto A, Bertoni F, Bhagat G, Campo E, De Leval L, Dirnhofer S, Pileri SA, Piris MA, Traverse-Glehen A, Tzankov A, Paulli M, Ponzoni M, Mazzucchelli L, Cavalli F, Zucca E, Rossi D. Genetic and phenotypic attributes of splenic marginal zone lymphoma. Blood. 2022 Feb 3;139(5):732-747. PMID:34653238.

Herranz D. INTERFERing with the progression of T-cell acute lymphoblastic leukemia: a multifaceted therapy. Haematologica. 2022 Jun 1;107(6):1232-1234. PMID:34647445.

Criss ZK 2nd, Bhasin N, Di Rienzi SC, Rajan A, Deans-Fielder K, Swaminathan G, Kamyabi N, Zeng XL, Doddapaneni H, Menon VK, Chakravarti D, Estrella C, Yu X, Patil K, Petrosino JF, Fleet JC, Verzi MP, Christakos S, Helmrath MA, Arimura S, DePinho RA, Britton RA, Maresso AW, Grande-Allen KJ, Blutt SE, Crawford SE, Estes MK, Ramani S, Shroyer NF. Drivers of transcriptional variance in human intestinal epithelial organoids. Physiol Genomics. 2021 Nov 1;53(11):486-508. PMID:34612061.

Gu W, Wang H, Huang X, Kraiczy J, Singh PNP, Ng C, Dagdeviren S, Houghton S, Pellon-Cardenas O, Lan Y, Nie Y, Zhang J, Banerjee KK, Onufer EJ, Warner BW, Spence J, Scherl E, Rafii S, Lee RT, Verzi MP, Redmond D, Longman R, Helin K, Shivdasani RA, Zhou Q. SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling. Cell Stem Cell. 2022 Jan 6;29(1):101-115.e10. PMID:34582804.

Yu Y, Dong H, Peng Y, Welsh WJ. QSAR-Based Computational Approaches to Accelerate the Discovery of Sigma-2 Receptor (S2R) Ligands as Therapeutic Drugs. Molecules. 2021 Aug 30;26(17):5270. PMID:34500703.

Poillet-Perez L, Sharp DW, Yang Y, Laddha SV, Ibrahim M, Bommareddy PK, Hu ZS, Vieth J, Haas M, Bosenberg MW, Rabinowitz JD, Cao J, Guan JL, Ganesan S, Chan CS, Mehnert JM, Lattime EC, White E. Autophagy promotes growth of tumors with high mutational burden by inhibiting a T-cell immune response. Nat Cancer. 2020 Sep;1(9):923-934. PMID:34476408.

Tong K, Kothari OA, Haro KS, Panda A, Bandari MM, Carrick JN, Hur JJ, Zhang L, Chan CS, Xing J, Gatza ML, Ganesan S, Verzi MP. SMAD4 is critical in suppression of BRAF-V600E serrated tumorigenesis. Oncogene. 2021 Oct;40(41):6034-6048. PMID:34453124.

Zhang S, Zhou YF, Cao J, Burley SK, Wang HY, Zheng XFS. mTORC1 Promotes ARID1A Degradation and Oncogenic Chromatin Remodeling in Hepatocellular Carcinoma. Cancer Res. 2021 Nov 15;81(22):5652-5665. PMID:34429326.

Kwon M, Rubio G, Nolan N, Auteri P, Volmar JA, Adem A, Javidian P, Zhou Z, Verzi MP, Pine SR, Libutti SK. FILIP1L Loss Is a Driver of Aggressive Mucinous Colorectal Adenocarcinoma and Mediates Cytokinesis Defects through PFDN1. Cancer Res. 2021 Nov 1;81(21):5523-5539. PMID:34417201.

Sabaawy HE, Ryan BM, Khiabanian H, Pine SR. JAK/STAT of all trades: linking inflammation with cancer development, tumor progression and therapy resistance. Carcinogenesis. 2021 Dec 31;42(12):1411-1419. PMID:34415330.

Panda A, Ganesan S. Genomic and Immunologic Correlates of Indoleamine 2,3-Dioxygenase Pathway Expression in Cancer. Front Genet. 2021 Jul 22;12:706435. PMID:34367262.

Li H, Bera K, Toro P, Fu P, Zhang Z, Lu C, Feldman M, Ganesan S, Goldstein LJ, Davidson NE, Glasgow A, Harbhajanka A, Gilmore H, Madabhushi A. Collagen fiber orientation disorder from H&E images is prognostic for early stage breast cancer: clinical trial validation. NPJ Breast Cancer. 2021 Aug 6;7(1):104. PMID:34362928.

George MA, Qureshi S, Omene C, Toppmeyer DL, Ganesan S. Clinical and Pharmacologic Differences of CDK4/6 Inhibitors in Breast Cancer. Front Oncol. 2021 Jul 12;11:693104. PMID:34327137.

Raines KS, Doniach S, Bhanot G. The transmission of SARS-CoV-2 is likely comodulated by temperature and by relative humidity. PLoS One. 2021 Jul 29;16(7):e0255212. PMID:34324570.

Verzi MP. GATA4 in Regional Affairs. Cell Mol Gastroenterol Hepatol. 2021;12(4):1505-1506. PMID:34310908.

Dias MP, Moser SC, Ganesan S, Jonkers J. Understanding and overcoming resistance to PARP inhibitors in cancer therapy. Nat Rev Clin Oncol. 2021 Dec;18(12):773-791. PMID:34285417.

Gorshein E, Matsuda K, Riedlinger G, Sokol L, Rodriguez-Rodriguez L, Eladoumikdachi F, Grandhi M, Ganesan S, Toppmeyer DL, Potdevin L, Toomey K, Hirshfield KM, Chan N. Durable Response to PD1 Inhibitor Pembrolizumab in a Metastatic, Metaplastic Breast Cancer. Case Rep Oncol. 2021 Jun 18;14(2):931-937. PMID:34248561.

Che H, Brown LG, Foran DJ, Nosher JL, Hacihaliloglu I. Liver disease classification from ultrasound using multi-scale CNN. Int J Comput Assist Radiol Surg. 2021 Sep;16(9):1537-1548. PMID:34097226.

Chen L, Luo S, Dupre A, Vasoya RP, Parthasarathy A, Aita R, Malhotra R, Hur J, Toke NH, Chiles E, Yang M, Cao W, Flores J, Ellison CE, Gao N, Sahota A, Su X, Bonder EM, Verzi MP. The nuclear receptor HNF4 drives a brush border gene program conserved across murine intestine, kidney, and embryonic yolk sac. Nat Commun. 2021 May 17;12(1):2886. PMID:34001900.

Esposito M, Ganesan S, Kang Y. Emerging strategies for treating metastasis. Nat Cancer. 2021 Mar;2(3):258-270. PMID:33899000.

da Silva-Diz V, Cao B, Lancho O, Chiles E, Alasadi A, Aleksandrova M, Luo S, Singh A, Tao H, Augeri D, Minuzzo S, Indraccolo S, Khiabanian H, Su X, Jin S, Herranz D. A novel and highly effective mitochondrial uncoupling drug in T-cell leukemia. Blood. 2021 Oct 14;138(15):1317-1330. PMID:33876224.

Mehta GA, Angus SP, Khella CA, Tong K, Khanna P, Dixon SAH, Verzi MP, Johnson GL, Gatza ML. SOX4 and SMARCA4 cooperatively regulate PI3k signaling through transcriptional activation of TGFBR2. NPJ Breast Cancer. 2021 Apr 9;7(1):40. PMID:33837205.

Schulman A, Bhanot G. Migration of households from New York City and the Second Peak in Covid-19 cases in New Jersey, Connecticut and New York Counties. medRxiv [Preprint]. 2021 Mar 31:2021.03.29.21254583. PMID:33821284.

Shiuan E, Reddy A, Dudzinski SO, Lim AR, Sugiura A, Hongo R, Young K, Liu XD, Smith CC, O'Neal J, Dahlman KB, McAlister R, Chen B, Ruma K, Roscoe N, Bender J, Ward J, Kim JY, Vaupel C, Bordeaux J, Ganesan S, Mayer TM, Riedlinger GM, Vincent BG, Davis NB, Haake SM, Rathmell JC, Jonasch E, Rini BI, Rathmell WK, Beckermann KE. Clinical Features and Multiplatform Molecular Analysis Assist in Understanding Patient Response to Anti-PD-1/PD-L1 in Renal Cell Carcinoma. Cancers (Basel). 2021 Mar 23;13(6):1475. PMID:33806963.

Sailaja BS, Aita R, Maledatu S, Ribnicky D, Verzi MP, Raskin I. Moringa isothiocyanate-1 regulates Nrf2 and NF-κB pathway in response to LPS-driven sepsis and inflammation. PLoS One. 2021 Apr 1;16(4):e0248691. PMID:33793581.

Suzuki K, Masuike Y, Mizuno R, Sachdeva UM, Chatterji P, Andres SF, Sun W, Klein-Szanto AJ, Besharati S, Remotti HE, Verzi MP, Rustgi AK. LIN28B induces a differentiation program through CDX2 in colon cancer. JCI Insight. 2021 May 10;6(9):e140382. PMID:33755595.

Hu X, Biswas A, Sharma A, Sarkodie H, Tran I, Pal I, De S. Mutational signatures associated with exposure to carcinogenic microplastic compounds bisphenol A and styrene oxide. NAR Cancer. 2021 Mar 1;3(1):zcab004. PMID:33718875.

Biswas A, De S. Drivers of dynamic intratumor heterogeneity and phenotypic plasticity. Am J Physiol Cell Physiol. 2021 May 1;320(5):C750-C760. PMID:33657326.

Popli P, Gutterman EM, Omene C, Ganesan S, Mills D, Marlink R. Receptor- Defined Breast Cancer in Five East African Countries and Its Implications for Treatment: Systematic Review and Meta-Analysis. JCO Glob Oncol. 2021 Feb;7:289-301. PMID:33591798.

Kanduri C, Sandve GK, Hovig E, De S, Layer RM. Editorial: Genomic Colocalization and Enrichment Analyses. Front Genet. 2021 Jan 26;11:617876. PMID:33574832.

Chen L, Cao W, Aita R, Aldea D, Flores J, Gao N, Bonder EM, Ellison CE, Verzi MP. Three-dimensional interactions between enhancers and promoters during intestinal differentiation depend upon HNF4. Cell Rep. 2021 Jan 26;34(4):108679. PMID:33503426.

Tottone L, Lancho O, Loh JW, Singh A, Kimura S, Roels J, Kuchmiy A, Strubbe S, Lawlor MA, da Silva-Diz V, Luo S, Gachet S, García-Prieto CA, Hagelaar R, Esteller M, Meijerink JPP, Soulier J, Taghon T, Van Vlierberghe P, Mullighan CG, Khiabanian H, Rocha PP, Herranz D. A Tumor Suppressor Enhancer of PTEN in T-cell development and leukemia. Blood Cancer Discov. 2021 Jan;2(1):92-109. PMID:33458694.

Riedlinger GM, Joshi S, Hirshfield KM, Barnard N, Ganesan S. Targetable alterations in invasive pleomorphic lobular carcinoma of the breast. Breast Cancer Res. 2021 Jan 13;23(1):7. PMID:33441174.

Qi X, Brown LG, Foran DJ, Nosher J, Hacihaliloglu I. Chest X-ray image phase features for improved diagnosis of COVID-19 using convolutional neural network. Int J Comput Assist Radiol Surg. 2021 Feb;16(2):197-206. PMID:33420641.

Xiong H, Mancini M, Gobert M, Shen S, Furtado GC, Lira SA, Parkhurst CN, Garambois V, Brengues M, Tadokoro CE, Trimarchi T, Gómez-López G, Singh A, Khiabanian H, Minuzzo S, Indraccolo S, Lobry C, Aifantis I, Herranz D, Lafaille JJ, Maraver A. Spleen plays a major role in DLL4-driven acute T-cell lymphoblastic leukemia. Theranostics. 2021 Jan 1;11(4):1594-1608. PMID:33408769.

Chan CS, Sun Y, Ke H, Zhao Y, Belete M, Zhang C, Feng Z, Levine AJ, Hu W. Genetic and stochastic influences upon tumor formation and tumor types in Li- Fraumeni mouse models. Life Sci Alliance. 2020 Dec 29;4(3):e202000952. PMID:33376133.

Peng Y, Zhang Q, Welsh WJ. Novel Sigma 1 Receptor Antagonists as Potential Therapeutics for Pain Management. J Med Chem. 2021 Jan 14;64(1):890-904. PMID:33372782.

Zheng Y, Chen Z, Han Y, Han L, Zou X, Zhou B, Hu R, Hao J, Bai S, Xiao H, Li WV, Bueker A, Ma Y, Xie G, Yang J, Chen S, Li H, Cao J, Shen L. Immune suppressive landscape in the human esophageal squamous cell carcinoma microenvironment. Nat Commun. 2020 Dec 8;11(1):6268. PMID:33293583.

Peng Y, Zhang Q, Zielinski RM, Howells RD, Welsh WJ. Identification of an irreversible PPARγ antagonist with potent anticancer activity. Pharmacol Res Perspect. 2020 Dec;8(6):e00693. PMID:33280279.

Clements KE, Schleicher EM, Thakar T, Hale A, Dhoonmoon A, Tolman NJ, Sharma A, Liang X, Imamura Kawasawa Y, Nicolae CM, Wang HG, De S, Moldovan GL. Identification of regulators of poly-ADP-ribose polymerase inhibitor response through complementary CRISPR knockout and activation screens. Nat Commun. 2020 Nov 30;11(1):6118. PMID:33257658.

Herranz D, Coppola RE, Escudero-Cid R, Ochoa-Romero K, D'Accorso NB, Pérez- Flores JC, Canales-Vázquez J, Palacio C, Abuin GC, Ocón P. Application of Crosslinked Polybenzimidazole-Poly(Vinyl Benzyl Chloride) Anion Exchange Membranes in Direct Ethanol Fuel Cells. Membranes (Basel). 2020 Nov 17;10(11):349. PMID:33212912.

Markowitz P, Patel M, Groisberg R, Aisner J, Jabbour SK, De S, Ganesan S, Malhotra J. Genomic characterization of malignant pleural mesothelioma and associated clinical outcomes. Cancer Treat Res Commun. 2020;25:100232. PMID:33166854.

Bhanot G, DeLisi C. Analysis of Covid-19 Data for Eight European Countries and the United Kingdom Using a Simplified SIR Model. Res Sq [Preprint]. 2020 Oct 29:rs.3.rs-97697. PMID:33140039.

Li S, De La Cruz J, Hutchens S, Mukhopadhyay S, Criss ZK, Aita R, Pellon- Cardenas O, Hur J, Soteropoulos P, Husain S, Dhawan P, Verlinden L, Carmeliet G, Fleet JC, Shroyer NF, Verzi MP, Christakos S. Analysis of 1,25-Dihydroxyvitamin D3 Genomic Action Reveals Calcium-Regulating and Calcium-Independent Effects in Mouse Intestine and Human Enteroids. Mol Cell Biol. 2020 Dec 21;41(1):e00372-20. PMID:33139494.

Ganesan S, Garber J. Poly (ADP-Ribose) Polymerase Inhibitor Activity in Prostate Cancers Harboring Mutations in DNA Repair Genes: Who Benefits? JCO Precis Oncol. 2020 Nov;4:1034-1037. doi: 10.1200/PO.20.00269. PMID:35050769.

Satagopan JM, Stroup A, Kinney AY, Dharamdasani T, Ganesan S, Bandera EV. Breast cancer among Asian Indian and Pakistani Americans: A surveillance, epidemiology and end results-based study. Int J Cancer. 2021 Apr 1;148(7):1598-1607. PMID:33099777.

Llanos AAM, Yao S, Singh A, Aremu JB, Khiabanian H, Lin Y, Omene C, Omilian AR, Khoury T, Hong CC, Ganesan S, Foran DJ, Higgins MJ, Ambrosone CB, Bandera EV, Demissie K. Gene expression of adipokines and adipokine receptors in the tumor microenvironment: associations of lower expression with more aggressive breast tumor features. Breast Cancer Res Treat. 2021 Feb;185(3):785-798. PMID:33067778.

Lu H, Ye C, Liu J, Rabson AB, Verzi M, De S, Shen Z. Requirement of Bccip for the Regeneration of Intestinal Progenitors. Am J Pathol. 2021 Jan;191(1):66-78. PMID:33039352.

Hu X, Xu Z, De S. Characteristics of mutational signatures of unknown etiology. NAR Cancer. 2020 Sep;2(3):zcaa026. PMID:33015626.

Dubois V, Staels B, Lefebvre P, Verzi MP, Eeckhoute J. Control of Cell Identity by the Nuclear Receptor HNF4 in Organ Pathophysiology. Cells. 2020 Sep 28;9(10):2185. PMID:32998360.

Akumalla S, Madison R, Lin DI, Schrock AB, Yakirevich E, Rosenzweig M, Balar AV, Frampton GM, Edgerly C, Erlich RL, Miller VA, Ganesan S, Ross JS, Ali SM. Characterization of Clinical Cases of Malignant PEComa via Comprehensive Genomic Profiling of DNA and RNA. Oncology. 2020;98(12):905-912. PMID:32966992.

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