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Key to Member Program Affiliation |
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CMI |
Cancer Metabolism and Immunology |
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Publication |
Member(s) Credited |
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Bartman CR, Faubert B, Rabinowitz JD (CMI), DeBerardinis RJ. Metabolic pathway analysis using stable isotopes in patients with cancer. Nat Rev Cancer. 2023 Dec 01; 23(12):863-878. DOI: 10.1038/s41568-023-00632-z. 2023 Oct 31. |
Rabinowitz JD (CMI) |
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Nakandakari-Higa S, Walker S, Canesso MCC, van der Heide V, Chudnovskiy A, Kim DY, Jacobsen JT, Parsa R, Bilanovic J, Parigi SM, Fiedorczuk K, Fuchs E, Bilate AM, Pasqual G, Mucida D, Kamphorst AO, Pritykin Y (CMI), Victora GD. Universal recording of immune cell interactions in vivo. Nature. 2024 Mar 01; 627(8003):399-406. DOI: 10.1038/s41586-024-07134-4. 2024 Mar 6. |
Pritykin Y (CMI) |
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Swanton C, Bernard E, Abbosh C, André F, Auwerx J, Balmain A, Bar-Sagi D, Bernards R, Bullman S, DeGregori J, Elliott C, Erez A, Evan G, Febbraio MA, Hidalgo A, Jamal-Hanjani M, Joyce JA, Kaiser M, Lamia K, Locasale JW, Loi S, Malanchi I, Merad M, Musgrave K, Patel KJ, White E (CMI), et al. Embracing cancer complexity: Hallmarks of systemic disease. Cell. 2024 Mar 28; 187(7):1589-1616. DOI: 10.1016/j.cell.2024.02.009. |
White E (CMI) |
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Nelson CM (CMI), Xiao B, Wickström SA, Dufrêne YF, Cosgrove DJ, Heisenberg CP, Dupont S, Shyer AE, Rodrigues AR, Trepat X, Diz-Muñoz A. Mechanobiology: Shaping the future of cellular form and function. Cell. 2024 May 23; 187(11):2652-2656. DOI: 10.1016/j.cell.2024.04.006. |
Nelson CM (CMI) |
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Banavar SP, Nelson CM (CMI). Mechanical properties pattern the skin. Science. 2023 Nov 24; 382(6673):880. DOI: 10.1126/science.adl2004. 2023 Nov 23. |
Nelson CM (CMI) |
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Routy B, Jackson T, Mählmann L, Baumgartner CK, Blaser M (CMI), Byrd A, Corvaia N, Couts K, Davar D, Derosa L, Hang HC, Hospers G, Isaksen M, Kroemer G, Malard F, McCoy KD, Meisel M, Pal S, Ronai Z, Segal E, Sepich-Poore GD, Shaikh F, Sweis RF, Trinchieri G, van den Brink M, Zhao L (CMI), et al. Melanoma and microbiota: Current understanding and future directions. Cancer Cell. 2024 Jan 08; 42(1):16-34. DOI: 10.1016/j.ccell.2023.12.003. 2023 Dec 28. |
Blaser M (CMI), Zhao L (CMI) |
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Guruprasad P, Carturan A, Zhang Y, Cho JH, Kumashie KG, Patel RP, Kim KH, Lee JS, Lee Y, Kim JH, Chung J, Joshi A, Cohen I, Shestov M, Ghilardi G, Harris J, Pajarillo R, Angelos M, Lee YG, Liu S, Rodriguez J, Wang M, Ballard HJ, Gupta A, Ugwuanyi OH, Liu D (CMI), et al. The BTLA-HVEM axis restricts CAR T cell efficacy in cancer. Nat Immunol. 2024 Jun 01; 25(6):1020-1032. DOI: 10.1038/s41590-024-01847-4. 2024 Jun 3. |
Liu D (CMI) |
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McBride MJ (CP), Hunter CJ, Zhang Z, TeSlaa T, Xu X, Ducker GS, Rabinowitz JD (CMI). Glycine homeostasis requires reverse SHMT flux. Cell Metab. 2024 Jan 02; 36(1):103-115.e4. DOI: 10.1016/j.cmet.2023.12.001. |
McBride MJ (CP), Rabinowitz JD (CMI) |
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Marshall G, Cao J (CMI). Mechanism-directed combinational immunotherapies in liver cancer hold promise. Cell Mol Immunol. 2023 Nov 01; 20(11):1395-1397. DOI: 10.1038/s41423-023-01068-z. 2023 Aug 7. |
Cao J (CMI) |
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Chen L, Qiu X, Dupre A, Pellon-Cardenas O, Fan X, Xu X, Rout P, Walton KD, Burclaff J, Zhang R, Fang W, Ofer R, Logerfo A, Vemuri K, Bandyopadhyay S, Wang J, Barbet G (CIPT, CMI), Wang Y, Gao N (CMI), Perekatt AO (GICG), Hu W (GICG), Magness ST, Spence JR, Verzi MP (GICG). TGFB1 induces fetal reprogramming and enhances intestinal regeneration. Cell Stem Cell. 2023 Nov 02; 30(11):1520-1537.e8. DOI: 10.1016/j.stem.2023.09.015. 2023 Oct 20. |
Barbet G (CIPT, CMI), |
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Wang J, Chang CY, Yang X, Zhou F, Liu J, Bargonetti J, Zhang L (CIPT), Xie P (CMI), Feng Z (GICG), Hu W (GICG). p53 suppresses MHC class II presentation by intestinal epithelium to protect against radiation-induced gastrointestinal syndrome. Nat Commun. 2024 Jan 02; 15(1):137. DOI: 10.1038/s41467-023-44390-w. 2024 Jan 2. |
Zhang L (CIPT), |
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Yang X, Wang J, Chang CY, Zhou F, Liu J, Xu H, Ibrahim M, Gomez M, Guo GL (CMI), Liu H (CIPT), Zong WX (CMI), Wondisford FE (CMI), Su X (CMI), White E (CMI), Feng Z (GICG), Hu W (GICG). Leukemia inhibitory factor suppresses hepatic de novo lipogenesis and induces cachexia in mice. Nat Commun. 2024 Jan 20; 15(1):627. DOI: 10.1038/s41467-024-44924-w. 2024 Jan 20. |
Guo GL (CMI), |
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Lan T, Arastu S, Lam J, Kim H, Wang W, Wang S, Bhatt V, Lopes EC, Hu Z, Sun M, Luo X, Ghergurovich JM, Su X (CMI), Rabinowitz JD (CMI), White E (CMI), Guo JY (CMI). Glucose-6-phosphate dehydrogenase maintains redox homeostasis and biosynthesis in LKB1-deficient KRAS-driven lung cancer. Nat Commun. 2024 Jul 12; 15(1):5857. DOI: 10.1038/s41467-024-50157-8. 2024 Jul 12. |
Su X (CMI), |
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Gupta M, Johnson ANT, Cruz ER, Costa EJ, Guest RL, Li SH, Hart EM, Nguyen T, Stadlmeier M, Bratton BP, Silhavy TJ, Wingreen NS, Gitai Z (CMI), Wühr M (CP). Global protein turnover quantification in Escherichia coli reveals cytoplasmic recycling under nitrogen limitation. Nat Commun. 2024 Jul 13; 15(1):5890. DOI: 10.1038/s41467-024-49920-8. 2024 Jul 13. |
Gitai Z (CMI), |
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Brumbaugh-Reed EH, Gao Y, Aoki K, Toettcher JE (CMI). Rapid and reversible dissolution of biomolecular condensates using light-controlled recruitment of a solubility tag. Nat Commun. 2024 Aug 07; 15(1):6717. DOI: 10.1038/s41467-024-50858-0. 2024 Aug 7. |
Toettcher JE (CMI) |
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Shen Y, Dinh HV, Cruz ER, Chen Z, Bartman CR, Xiao T, Call CM, Ryseck RP, Pratas J, Weilandt D, Baron H, Subramanian A, Fatma Z, Wu ZY, Dwaraknath S, Hendry JI, Tran VG, Yang L, Yoshikuni Y, Zhao H, Maranas CD, Wühr M (CP), Rabinowitz JD (CMI). Mitochondrial ATP generation is more proteome efficient than glycolysis. Nat Chem Biol. 2024 Sep 01; 20(9):1123-1132. DOI: 10.1038/s41589-024-01571-y. 2024 Mar 6. |
Wühr M (CP), Rabinowitz JD (CMI) |
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Paramore SV, Trenado-Yuste C, Sharan R, Nelson CM (CMI), Devenport D (CMI). Vangl-dependent mesenchymal thinning shapes the distal lung during murine sacculation. Dev Cell. 2024 May 20; 59(10):1302-1316.e5. DOI: 10.1016/j.devcel.2024.03.010. 2024 Apr 2. |
Nelson CM (CMI), Devenport D (CMI) |
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Nguyen R, Doubrovina E, Mousset CM, Jin BY, Okada R, Zhang X, Clavel A, Reyes-Gonzalez JM, Dyomin V, Diaz L, Zhang L, Abbas S, Sun M, Hsieh CM, Ho M, Shern JF, Gulley JL, Hinrichs CS (CIPT, CMI). Cooperative Armoring of CAR and TCR T Cells by T Cell-Restricted IL15 and IL21 Universally Enhances Solid Tumor Efficacy. Clin Cancer Res. 2024 Apr 15; 30(8):1555-1566. DOI: 10.1158/1078-0432.CCR-23-1872. |
Hinrichs CS (CIPT, CMI) |
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Balasubramanian I, Bandyopadhyay S, Flores J, Bianchi-Smak J, Lin X, Liu H, Sun S, Golovchenko NB, Liu Y, Wang D, Patel R, Joseph I, Suntornsaratoon P, Vargas J, Green PH, Bhagat G, Lagana SM, Ying W, Zhang Y, Wang Z, Li WV (GICG), Singh S, Zhou Z (GICG), Kollias G, Farr LA, Zhang L (CIPT), Gao N (CMI), et al. Infection and inflammation stimulate expansion of a CD74+ Paneth cell subset to regulate disease progression. EMBO J. 2023 Nov 02; 42(21):e113975. DOI: 10.15252/embj.2023113975. 2023 Sep 18. |
Li WV (GICG), |
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Han X, Wang D, Yang L, Wang N, Shen J, Wang J, Zhang L, Chen L, Gao S, Zong WX (CMI), Wang Y. Activation of polyamine catabolism promotes glutamine metabolism and creates a targetable vulnerability in lung cancer. Proc Natl Acad Sci U S A. 2024 Mar 26; 121(13):e2319429121. DOI: 10.1073/pnas.2319429121. 2024 Mar 21. |
Zong WX (CMI) |
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Sakamoto K, Butera MA, Zhou C, Maurizi G, Chen B, Ling L, Shawkat A, Patlolla L, Thakker K, Calle V, Morgan DA, Rahmouni K, Schwartz GJ, Tahiri A, Buettner C (CMI). Overnutrition causes insulin resistance and metabolic disorder through increased sympathetic nervous system activity. Cell Metab. 2024 OCT 15; . DOI: 10.1016/j.cmet.2024.09.012. 2024 Oct 15. PubMed PMID: 39437790. |
Buettner C (CMI) |
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Zhang L, Norberg SM, Karimipour F, Davies JS, Kuznetsov A, Lassoued W, Burnett D, Homan P, Cam M, Sinkoe A, Xue P, Gulley JL, Hinrichs CS (CIPT, CMI). Adoptive transfer of membrane-restricted IL-12-TCR T cells promotes antigen spreading and elimination of antigen-negative tumor variants. J Immunother Cancer. 2024 NOV 18; 12(11). DOI: 10.1136/jitc-2024-009868. 2024 Nov 18. PubMed PMID: 39557544; PMCID: PMC11574437. |
Hinrichs CS (CIPT, CMI) |
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Douglas A, Stevens B, Rendas M, Kane H, Lynch E, Kunkemoeller B, Wessendorf-Rodriguez K, Day EA, Sutton C, Brennan M, O'Brien K, Kohlgruber AC, Prendeville H, Garza AE, O'Neill LAJ, Mills KHG, Metallo CM, Veiga-Fernandes H, Lynch L (CMI). Rhythmic IL-17 production by γδ T cells maintains adipose de novo lipogenesis. Nature. 2024 OCT 30; . DOI: 10.1038/s41586-024-08131-3. 2024 Oct 30. PubMed PMID: 39478228. |
Lynch L (CMI) |
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Yang P, Gao S, Shen J, Liu T, Lu K, Han X, Wang J (CP), Ni HM, Ding WX, Li H (CP), Pan JA, Peng K, Zong WX (CMI). TRIM21-mediated ubiquitination of SQSTM1/p62 abolishes its Ser403 phosphorylation and enhances palmitic acid cytotoxicity. Autophagy. 2024 SEP 10; :1-13. DOI: 10.1080/15548627.2024.2394308. 2024 Sep 10. PubMed PMID: 39172027. |
Wang J (CP), |
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Wu G, Xu T, Zhao N, Lam YY, Ding X, Wei D, Fan J, Shi Y, Li X, Li M, Ji S, Wang X, Fu H, Zhang F, Shi Y, Zhang C, Peng Y, Zhao L (CMI). A core microbiome signature as an indicator of health. Cell. 2024 OCT 07; . DOI: 10.1016/j.cell.2024.09.019. 2024 Oct 7. PubMed PMID: 39378879. |
Zhao L (CMI) |
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Balaich J, Estrella M, Wu G, Jeffrey PD, Biswas A, Zhao L, Korennykh A (CMG), Donia MS (CMG). The human microbiome encodes resistance to the antidiabetic drug acarbose. Nature. 2021 DEC 01; 600(7887):110-115. DOI: 10.1038/s41586-021-04091-0. 2021 Nov 24. PubMed PMID: 34819672. |
Zhao, L (CMI), |
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Chen L, Lu W, Wang L, Xing X, Chen Z, Teng X, Zeng X, Muscarella AD, Shen Y, Cowan A, McReynolds MR, Kennedy BJ, Lato AM, Campagna SR, Singh M (GICG), Rabinowitz JD (CMG). Metabolite discovery through global annotation of untargeted metabolomics data. Nat Methods. 2021 NOV 01; 18(11):1377-1385. DOI: 10.1038/s41592-021-01303-3. 2021 Oct 28. PubMed PMID: 34711973; PMCID: PMC8733904. |
Rabinowitz, J.D. (CMI) |
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Wang L, Xing X, Zeng X, Jackson SR, TeSlaa T, Al-Dalahmah O, Samarah LZ, Goodwin K, Yang L, McReynolds MR, Li X, Wolff JJ, Rabinowitz JD (CMG), Davidson SM (CMG). Spatially resolved isotope tracing reveals tissue metabolic activity. Nat Methods. 2022 FEB 01; 19(2):223-230. DOI: 10.1038/s41592-021-01378-y. 2022 Feb 7. PubMed PMID: 35132243. |
Rabinowitz, J.D. (CMI), |
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Zeng X, Xing X, Gupta M, Keber FC, Lopez JG, Lee YJ, Roichman A, Wang L, Neinast MD, Donia MS (CMG), Wühr M (CP), Jang C, Rabinowitz JD (CMG). Gut bacterial nutrient preferences quantified in vivo. Cell. 2022 Sep 1;185(18):3441-3456.e19. doi: 10.1016/j.cell.2022.07.020. PMID: 36055202; PMCID: PMC9450212. |
Rabinowitz, J.D. (CMI), Donia, M.S. (CMI) |
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Shen M, Smith HA, Wei Y, Jiang YZ, Zhao S, Wang N, Rowicki M, Tang Y, Hang X, Wu S, Wan L, Shao ZM, Kang Y (CMG). Pharmacological disruption of the MTDH-SND1 complex enhances tumor antigen presentation and synergizes with anti-PD-1 therapy in metastatic breast cancer. Nat Cancer. 2022 JAN 01; 3(1):60-74. DOI: 10.1038/s43018-021-00280-y. 2021 Nov 29. PubMed PMID: 35121988; PMCID: PMC8818088. |
Kang, Y (CMI) |
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Shen M, Wei Y, Kim H (CP), Wan L, Jiang YZ, Hang X, Raba M, Remiszewski S, Rowicki M, Wu CG, Wu S, Zhang L, Lu X, Yuan M, Smith HA, Zheng A, Bertino J (CP), Jin JF, Xing Y, Shao ZM, Kang Y (CMG). Small-molecule inhibitors that disrupt the MTDH-SND1 complex suppress breast cancer progression and metastasis. Nat Cancer. 2022 JAN 01; 3(1):43-59. DOI: 10.1038/s43018-021-00279-5. 2021 Nov 29. PubMed PMID: 35121987; PMCID: PMC8818087. |
Kang, Y (CMI) |
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Sharma S, Yang J, Grudzien-Nogalska E, Shivas J, Kwan KY, Kiledjian M (CMG). Xrn1 is a deNADding enzyme modulating mitochondrial NAD-capped RNA. Nat Commun. 2022 FEB 16; 13(1):889. DOI: 10.1038/s41467-022-28555-7. 2022 Feb 16. PubMed PMID: 35173156; PMCID: PMC8850482. |
Kiledjian, M (CMI) |
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Guzman S, Dragan M, Kwon H, de Oliveira V, Rao S, Bhatt V, Kalemba KM, Shah A, Rustgi VK, Wang H (CIPT), Bech PR, Abbara A, Izzi-Engbeaya C, Manousou P, Guo JY (CMG), Guo GL (CMG), Radovick S (CMG), Dhillo WS, Wondisford FE (CMG), Babwah AV, Bhattacharya M (CMG). Targeting hepatic kisspeptin receptor ameliorates nonalcoholic fatty liver disease in a mouse model. J Clin Invest. 2022 MAY 16; 132(10). DOI: 10.1172/JCI145889. PubMed PMID: 35349482; PMCID: PMC9106350. |
Guo, Y (CMI), |
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Palmer MA, Nerger BA, Goodwin K, Sudhakar A, Lemke SB, Ravindran PT, Toettcher JE (CMG), Košmrlj A, Nelson CM (CMG). Stress ball morphogenesis: How the lizard builds its lung. Sci Adv. 2021 DEC 24; 7(52):eabk0161. DOI: 10.1126/sciadv.abk0161. 2021 Dec 22. PubMed PMID: 34936466; PMCID: PMC8694616. |
Toettcher, J.E. (CMI), |
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Davies JS, Karimipour F, Zhang L, Nagarsheth N, Norberg S, Serna C, Strauss J, Chiou S, Gulley JL, Hinrichs CS (CMG). Non-synergy of PD-1 blockade with T-cell therapy in solid tumors. J Immunother Cancer. 2022 JUL 01; 10(7). DOI: 10.1136/jitc-2022-004906. PubMed PMID: 35793866; PMCID: PMC9260838. |
Hinrichs, C (CMI, CIPT) |
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Ghergurovich JM, Xu X, Wang JZ, Yang L, Ryseck RP, Wang L, Rabinowitz JD (CMG). Methionine synthase supports tumour tetrahydrofolate pools. Nat Metab. 2021 NOV 01; 3(11):1512-1520. DOI: 10.1038/s42255-021-00465-w. 2021 Nov 18. PubMed PMID: 34799699; PMCID: PMC9284419. |
Rabinowitz, J.D. (CMI) |
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Li X, Hui S, Mirek ET, Jonsson WO, Anthony TG (CMG), Lee WD, Zeng X, Jang C, Rabinowitz JD (CMG). Circulating metabolite homeostasis achieved through mass action. Nat Metab. 2022 JAN 01; 4(1):141-152. DOI: 10.1038/s42255-021-00517-1. 2022 Jan 20. PubMed PMID: 35058631; PMCID: PMC9244777. |
Rabinowitz, J.D. (CMI), |
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Zhang Z, TeSlaa T, Xu X, Zeng X, Yang L, Xing G, Tesz GJ, Clasquin MF, Rabinowitz JD (CMG). Serine catabolism generates liver NADPH and supports hepatic lipogenesis. Nat Metab. 2021 DEC 01; 3(12):1608-1620. DOI: 10.1038/s42255-021-00487-4. 2021 Nov 29. PubMed PMID: 34845393; PMCID: PMC8721747. |
Rabinowitz, J.D. (CMI) |
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Dai W, Shen J, Yan J, Bott AJ, Maimouni S, Daguplo HQ, Wang Y, Khayati K, Guo JY (CMG), Zhang L (CIPT), Wang Y, Valvezan A (CMG), Ding WX, Chen X, Su X (CMG), Gao S, Zong WX (CMG). Glutamine synthetase limits β-catenin-mutated liver cancer growth by maintaining nitrogen homeostasis and suppressing mTORC1. J Clin Invest. 2022 Dec 15;132(24):e161408. doi: 10.1172/JCI161408. PMID: 36256480; PMCID: PMC9754002. |
Guo, Y (CMI), |
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Chitrakar A, Solorio-Kirpichyan K, Prangley E, Rath S, Du J, Korennykh A (CMG). Introns encode dsRNAs undetected by RIG-I/MDA5/interferons and sensed via RNase L. Proc Natl Acad Sci U S A. 2021 NOV 16; 118(46). DOI: 10.1073/pnas.2102134118. PubMed PMID: 34772806; PMCID: PMC8609619. |
Korennykh, A.V. (CMI) |
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Du J, Estrella M, Solorio-Kirpichyan K, Jeffrey PD, Korennykh A (CMG). Structure of human NADK2 reveals atypical assembly and regulation of NAD kinases from animal mitochondria. Proc Natl Acad Sci U S A. 2022 JUN 28; 119(26):e2200923119. DOI: 10.1073/pnas.2200923119. 2022 Jun 21. PubMed PMID: 35733246; PMCID: PMC9245612. |
Korennykh, A.V. (CMI) |
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Nofal M, Wang T, Yang L, Jankowski CSR, Hsin-Jung Li S, Han S, Parsons L, Frese AN, Gitai Z (CMG), Anthony TG (CMG), Wühr M (CP), Sabatini DM, Rabinowitz JD (CMG). GCN2 adapts protein synthesis to scavenging-dependent growth. Cell Syst. 2022 FEB 16; 13(2):158-172.e9. DOI: 10.1016/j.cels.2021.09.014. 2021 Oct 26. PubMed PMID: 34706266; PMCID: PMC8961722. |
Gitai, Z (CMI), |
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Farahani PE, Lemke SB, Dine E, Uribe G, Toettcher JE (CMG), Nelson CM (CMG). Substratum stiffness regulates Erk signaling dynamics through receptor-level control. Cell Rep. 2021 DEC 28; 37(13):110181. DOI: 10.1016/j.celrep.2021.110181. PubMed PMID: 34965432; PMCID: PMC8756379. |
Toettcher, J.E. (CMI), |
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Onken B, Sedore CA, Coleman-Hulbert AL, Hall D, Johnson E, Jones EG, Banse SA, Huynh P, Guo S, Xue J, Chen E, Harinath G, Foulger AC, Chao EA, Hope J, Bhaumik D, Plummer T, Inman D, Morshead M, Guo M, Lithgow GJ, Phillips PC, Driscoll M (CMG). Metformin treatment of diverse Caenorhabditis species reveals the importance of genetic background in longevity and healthspan extension outcomes. Aging Cell. 2022 JAN 01; 21(1):e13488. DOI: 10.1111/acel.13488. 2021 Nov 27. PubMed PMID: 34837316; PMCID: PMC8761014. |
Driscoll, M.A. (CMI) |
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Yue X, Wang J, Chang CY, Liu J, Yang X, Zhou F, Qiu X, Bhatt V, Guo JY (CMG), Su X (CMG), Zhang L, Feng Z (GICG), Hu W (GICG). Leukemia inhibitory factor drives glucose metabolic reprogramming to promote breast tumorigenesis. Cell Death Dis. 2022 APR 19; 13(4):370. DOI: 10.1038/s41419-022-04820-x. 2022 Apr 19. PubMed PMID: 35440095; PMCID: PMC9018736. |
Guo, Y (CMI), |
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Das S, Feng Q, Balasubramanian I, Lin X, Liu H, Pellón-Cardenas O, Yu S, Zhang X, Liu Y, Wei Z, Bonder EM, Verzi MP (GICG), Hsu W, Zhang L, Wang TC, Gao N (CMG). Colonic healing requires Wnt produced by epithelium as well as Tagln+ and Acta2+ stromal cells. Development. 2022 JAN 01; 149(1). DOI: 10.1242/dev.199587. 2022 Jan 12. PubMed PMID: 34910127; PMCID: PMC8881740. |
Gao, N (CMI) |
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Huo Y, Sawant A, Tan Y, Mahdi AH, Li T, Ma H, Bhatt V, Yan R, Coleman J, Dreyfus CF, Guo JY (CMG), Mouradian MM (CMG), White E (CMG), Xia B (GICG). Tumor suppressor PALB2 maintains redox and mitochondrial homeostasis in the brain and cooperates with ATG7/autophagy to suppress neurodegeneration. PLoS Genet. 2022 APR 01; 18(4):e1010138. DOI: 10.1371/journal.pgen.1010138. 2022 Apr 11. PubMed PMID: 35404932; PMCID: PMC9022806. |
Guo, Y (CMI), |
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Wang L, Shannar AAF, Wu R, Chou P, Sarwar MS, Kuo HC, Peter RM, Wang Y, Su X (CMG), Kong AN. Butyrate Drives Metabolic Rewiring and Epigenetic Reprogramming in Human Colon Cancer Cells. Mol Nutr Food Res. 2022 JUN 01; 66(12):e2200028. DOI: 10.1002/mnfr.202200028. 2022 Apr 28. PubMed PMID: 35429118; PMCID: PMC9233026. |
Su, X (CMI) |
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Malhotra J (CIPT), Ryan B, Patel M, Chan N (CIPT), Guo Y (CMG), Aisner J (CIPT), Jabbour SK (CIPT), Pine S (GICG). Clinical outcomes and immune phenotypes associated with STK11 co-occurring mutations in non-small cell lung cancer. J Thorac Dis. 2022 JUN 01; 14(6):1772-1783. DOI: 10.21037/jtd-21-1377. PubMed PMID: 35813711; PMCID: PMC9264081. |
Guo, Y (CMI) |
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Krzyzanowska AK, Haynes Ii RAH, Kovalovsky D, Lin HC, Osorio L, Edelblum KL, Corcoran LM, Rabson AB, Denzin LK (CMG), Sant'Angelo DB (CMG). Zbtb20 identifies and controls a thymus-derived population of regulatory T cells that play a role in intestinal homeostasis. Sci Immunol. 2022 MAY 06; 7(71):eabf3717. DOI: 10.1126/sciimmunol.abf3717. 2022 May 6. PubMed PMID: 35522722. |
Rabson, A.B. (CMI), |
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Ghaddar B, Biswas A, Harris C, Omary MB, Carpizo DR, Blaser MJ, De S. Tumor microbiome links cellular programs and immunity in pancreatic cancer. Cancer Cell. 2022;40(10):1240-53.e5. doi: 10.1016/j.ccell.2022.09.009. PubMed PMID: 36220074; PMCID: PMC9556978. |
Blaser MJ (CMI), |
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Jankowski CSR, Rabinowitz JD. Selenium Modulates Cancer Cell Response to Pharmacologic Ascorbate. Cancer Res. 2022;82(19):3486-98. doi: 10.1158/0008-5472.Can-22-0408. PubMed PMID: 35916672; PMCID: PMC9532358. |
Rabinowitz JD (CMI) |
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Li ML, Ragupathi A, Patel N, Hernandez T, Magsino J, Werlen G, Brewer G, Jacinto E. The RNA-binding protein AUF1 facilitates Akt phosphorylation at the membrane. J Biol Chem. 2022;298(10):102437. doi: 10.1016/j.jbc.2022.102437. PubMed PMID: 36041631; PMCID: PMC9513781. |
Brewer G (ZY), |
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Zeng X, Xing X, Gupta M, Keber FC, Lopez JG, Lee YJ, Roichman A, Wang L, Neinast MD, Donia MS, Wühr M, Jang C, Rabinowitz JD. Gut bacterial nutrient preferences quantified in vivo. Cell. 2022;185(18):3441-56.e19. doi: 10.1016/j.cell.2022.07.020. PubMed PMID: 36055202; PMCID: PMC9450212. |
Donia MS (CMI), |
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Peng J, Qin C, Ramatchandirin B, Pearah A, Guo S, Hussain M, Yu L, Wondisford FE, He L. Activation of the canonical ER stress IRE1-XBP1 pathway by insulin regulates glucose and lipid metabolism. J Biol Chem. 2022;298(9):102283. doi: 10.1016/j.jbc.2022.102283. PubMed PMID: 35863429; PMCID: PMC9396404. |
Wondisford FE (CMI) |
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Sharma S, Yang J, Doamekpor SK, Grudizen-Nogalska E, Tong L, Kiledjian M. Identification of a novel deFADding activity in human, yeast and bacterial 5' to 3' exoribonucleases. Nucleic Acids Res. 2022;50(15):8807-17. doi: 10.1093/nar/gkac617. PubMed PMID: 35904778; PMCID: PMC9410882. |
Kiledjian M (CMI) |
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Yin Z, Bird JG, Kaelber JT, Nickels BE, Ebright RH. In transcription antitermination by Qλ, NusA induces refolding of Qλ to form a nozzle that extends the RNA polymerase RNA-exit channel. Proc Natl Acad Sci U S A. 2022;119(33):e2205278119. doi: 10.1073/pnas.2205278119. PubMed PMID: 35951650; PMCID: PMC9388147. |
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Simi AK, Anlaş AA, Stallings-Mann M, Zhang S, Hsia T, Cichon M, Radisky DC, Nelson CM. A Soft Microenvironment Protects from Failure of Midbody Abscission and Multinucleation Downstream of the EMT-Promoting Transcription Factor Snail. Cancer Res. 2018;78(9):2277-89. doi: 10.1158/0008-5472.Can-17-2899. PubMed PMID: 29483094; PMCID: PMC5932229. |
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Panda A, Mehnert JM, Hirshfield KM, Riedlinger G, Damare S, Saunders T, Kane M, Sokol L, Stein MN, Poplin E, Rodriguez-Rodriguez L, Silk AW, Aisner J, Chan N, Malhotra J, Frankel M, Kaufman HL, Ali S, Ross JS, White EP, Bhanot G, Ganesan S. Immune Activation and Benefit From Avelumab in EBV-Positive Gastric Cancer. J Natl Cancer Inst. 2018;110(3):316-20. doi: 10.1093/jnci/djx213. PubMed PMID: 29155997; PMCID: PMC6658862. |
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Jang C, Hui S, Lu W, Cowan AJ, Morscher RJ, Lee G, Liu W, Tesz GJ, Birnbaum MJ, Rabinowitz JD. The Small Intestine Converts Dietary Fructose into Glucose and Organic Acids. Cell Metab. 2018;27(2):351-61.e3. doi: 10.1016/j.cmet.2017.12.016. PubMed PMID: 29414685; PMCID: PMC6032988. |
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Arrigucci R, Lakehal K, Vir P, Handler D, Davidow AL, Herrera R, Estrada-Guzmán JD, Bushkin Y, Tyagi S, Lardizabal AA, Gennaro ML. Active Tuberculosis Is Characterized by Highly Differentiated Effector Memory Th1 Cells. Front Immunol. 2018;9:2127. doi: 10.3389/fimmu.2018.02127. PubMed PMID: 30283456; PMCID: PMC6156157. |
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Zheng H, Bae Y, Kasimir-Bauer S, Tang R, Chen J, Ren G, Yuan M, Esposito M, Li W, Wei Y, Shen M, Zhang L, Tupitsyn N, Pantel K, King C, Sun J, Moriguchi J, Jun HT, Coxon A, Lee B, Kang Y. Therapeutic Antibody Targeting Tumor- and Osteoblastic Niche-Derived Jagged1 Sensitizes Bone Metastasis to Chemotherapy. Cancer Cell. 2017;32(6):731-47.e6. doi: 10.1016/j.ccell.2017.11.002. PubMed PMID: 29232552; PMCID: PMC5729937. |
Zhang L (CIPT), |
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Cheng LC, Tan VM, Ganesan S, Drake JM. Integrating phosphoproteomics into the clinical management of prostate cancer. Clinical and translational medicine. 2017;6(1):9. doi: 10.1186/s40169-017-0138-5. PubMed PMID: 28197968; PMCID: PMC5309189. |
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Liu J, Zhang C, Zhao Y, Yue X, Wu H, Huang S, Chen J, Tomsky K, Xie H, Khella CA, Gatza ML, Xia D, Gao J, White E, Haffty BG, Hu W, Feng Z. Parkin targets HIF-1α for ubiquitination and degradation to inhibit breast tumor progression. Nat Commun. 2017;8(1):1823. doi: 10.1038/s41467-017-01947-w. PubMed PMID: 29180628; PMCID: PMC5703960. |
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