Based at Princeton University, the Ludwig Princeton Branch is wholly dedicated to the study of cancer metabolism. Combined with Ludwig’s leadership in cancer epigenetics and immunotherapy, advances in cancer metabolism generated at the Ludwig Princeton Branch inform new strategies for cancer prevention and treatment.
Postdoctoral positions are available under the mentorship of Dr. Cristina Montagna in the Division of Radiation Cancer Biology at the Department of Radiation Oncology, to study mechanisms of genomic instability in mammalian systems. Projects focus on the contribution of genomic instability in the form of aneuploidies, single-nucleotide variants (SNVs) and small insertions and deletions (INDELs) to early transformation and progression to tumorigenesis. The area of expertise of the laboratory is molecular cytogenetics and single cell genomics.
Research in the Montagna Laboratory at the Rutgers Cancer Institute aims to understand the mechanisms by which genomic instability promotes tumor initiation and progression. Using advanced molecular cytogenetic approaches and single cell genomics methodologies applied to human and murine in culture and in vivo models we investigate the roles of large copy number alterations and papilloma virus insertional mutagenesis to tumor initiation and progression.
