Skip to main content
 CHANGE IN VISITATION GUIDELINES: Please read before visiting Rutgers Cancer Institute.

Researcher Directory

Sang-Hyuk Lee, PhD

Associate Member, Cancer Pharmacology Program

Member since 2016

Academic Appointment

Assistant Professor
Department of Physics and Astronomy
School of Arts and Sciences
Rutgers, The State University of New Jersey


Research Interests

  • My research focuses on understanding cellular processes at the single-molecule level by using novel single-molecule manipulation and imaging methods such as Optical Tweezers, smFRET, and PALM/STORM microscopy.
  • We are currently interested in innate immune response: 1) understanding how RIG-I recognizes viral RNA and how they come to be an active complex for further downstream signaling, 2) studying the dynamics of viral RNA and RIG-I distribution through single-molecule tracking inside a living cell, and 3) understanding RIG-I to MAVS on mitochondria membrane.
  • Our lab also tries to develop new single-molecule methods and advanced optical imaging methods for broader applications.

Selected Publications

The content for the Researcher Directory is maintained by Gina Londino-Greenberg (