Sang-Hyuk Lee, PhD
Associate Member, Cancer Pharmacology ProgramMember since 2016
Department of Physics and Astronomy
School of Arts and Sciences
Rutgers, The State University of New Jersey
- Institute for Quantitative Biomedicine Profile
- Department of Physics and Astronomy Profile
- Lee Lab
- Research with Rutgers Profile
- My research focuses on understanding cellular processes at the single-molecule level by using novel single-molecule manipulation and imaging methods such as Optical Tweezers, smFRET, and PALM/STORM microscopy.
- We are currently interested in innate immune response: 1) understanding how RIG-I recognizes viral RNA and how they come to be an active complex for further downstream signaling, 2) studying the dynamics of viral RNA and RIG-I distribution through single-molecule tracking inside a living cell, and 3) understanding RIG-I to MAVS on mitochondria membrane.
- Our lab also tries to develop new single-molecule methods and advanced optical imaging methods for broader applications.
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