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A Phase 3, Randomized, Open-label, Multicenter Study to Evaluate the Efficacy and Safety of MK-2870 Maintenance Treatment With or Without Bevacizumab Versus Standard of Care After Second-line Platinum-based Doublet Chemotherapy in Participants With Platinum-sensitive Recurrent Ovarian Cancer (TroFuse-022/GOG-3103/ENGOT-ov84)

Part 1: To evaluate the safety and tolerability of sacituzumab tirumotecan maintenance treatment with bevacizumab.

Part 2: To compare sacituzumab tirumotecan maintenance treatment with or without bevacizumab to SoC (observation
with or without bevacizumab) with respect to PFS per RECIST 1.1 as assessed by BICR.

Protocol Number: 102501
Phase: Phase III
Applicable Disease Sites: Other Female Genital
Drugs Involved: BEVACIZUMAB
Sacitzumab govitecan/IMMU-132
Principal Investigator: Aliza Leiser
Scope: National
Therapies Involved: Chemotherapy multiple agents systemic
Participating Institutions:
  • RWJBarnabas Health
    • Jersey City Medical Center, Jersey City
    • Monmouth Medical Center
    • Monmouth Medical Center Southern Campus
  • Rutgers University
Inclusion & Exclusion Criteria

Please note that we have obtained the inclusion and exclusion criteria information from the National Institutes of Health’s clinical trials web site ClinicalTrials.gov. The listed criteria may not necessarily reflect recent amendments to the protocol and the current criteria.

For further information about clinical trials, please contact us at 732-235-7356.