Research Interests

• Multiscale Simulation of Environmental and Biological Systems and Interactions: 1) Mathematical modeling of multimedia transport, fate and uptake of environmental pollutants - photochemical oxidants, air toxics, pesticides, solvents, heavy metals, nanomaterials, spores and pollens 2) Physiologically-based pharmacokinetics, inhalation, ingestion and dermal absorption 3) Mechanistic pharmacodynamics 4) Virtual tissues 5) Computational systems toxicology and toxicogenomics
• Enviroinformatics and the Exposome: 1) Spatiotemporal data mining and analysis 2) Geographic information and database management systems 3) Multiroute/multipathway modeling of human exposures to chemical, radiological and biological agents 4) Climatic change impacts on environmental quality and human exposure and health 5) Environmental cheminformatics and bioinformatics
• Risk Analysis for Environmental and Occupational Health: 1) Uncertainty characterization and analysis 2) Diagnostic and prognostic risk assessment for exposures to carcinogens, neurotoxicants, allergens, irritants, endocrine disruptors 3) Indiviudal and population based simulation modeling