Precision Medicine Publications


Morgan KM, Riedlinger GM, Rosenfeld J, Ganesan S, and Pine SR. Patient-derived xenograft models of non-small cell lung cancer and their potential utility in personalized medicine. Front Oncol, 19;7:2, 20017. PMC5243815

Morgan KM, Fischer BS, Lee FY, Shah JJ, Bertino JR, Rosenfeld J, Singh A, Khiabanian H, and Pine SR. Gamma secretase inhibition by BMS-906024 enhances efficacy of paclitaxel in lung adenocarcinoma. Mol Cancer Ther, 2017 PMID: 28978720

Kulkarni A, Al-Hraishawi H, Simhadri S, Hirshfield KM, Chen S, Pine S, Jeyamohan C, Sokol L, Ali S, Teo ML, White E, Rodriguez-Rodriguez L, Mehnert JM, and Ganesan S. BRAF Fusion as a Novel Mechanism of Acquired Resistance to Vemurafenib in BRAFV600E Mutant Melanoma. Clin Cancer Res, 15;23(18):5631-5638, 2017. PMID: 28539463

Hirshfield K, Tolkunov D, Zhong H, et al. Clinical utility of comprehensive genomic profiling for management of rare or refractory cancers. Oncologist. 2016. PMID: 27566247.

Yang XZ, Li XX, Zhang YJ, et al. Rab1 in cell signaling, cancer and other diseases. Oncogene. 2016PubMed PMID: 27041585.

Rodriguez-Rodriguez L, Hirshfield KM, Rojas V, et al. Use of comprehensive genomic profiling to direct point-of-care management of patients with gynecologic cancers. Gynecol Oncol. 2016;141(1):2-9. PubMed PMID: 27016222.  

Paratala BS, Dolfi SC, Khiabanian H, Rodriguez-Rodriguez L, Ganesan S, Hirshfield KM. Emerging Role of Genomic Rearrangements in Breast Cancer: Applying Knowledge from Other Cancers. Biomark Cancer. 2016;8(Supple 1):1-14. PubMed PMID: 26917980.  

Mehnert JM, Panda A, Zhong H, et al. Immune activation and response to pembrolizumab in POLE-mutant endometrial cancer. J Clin Invest. 2016;126(6):2334-2340. PMID: 27159395.  

Ganguly B, Dolfi SC, Rodriguez-Rodriguez L, Ganesan S, Hirshfield KM. Role of Biomarkers in the Development of PARP Inhibitors. Biomark Cancer. 2016;8(Suppl 1):15-25. PubMed PMID: 26997874.  

Xie X, Koh JY, Price S, White E, Mehnert JM. Atg7 Overcomes Senescence and Promotes Growth of BrafV600E-Driven Melanoma. Cancer Discov. 2015;5(4):410-423. PubMed PMID: 25673642.  

White E, Mehnert JM, Chan CS. Autophagy, Metabolism, and Cancer. Clin Cancer Res. 2015;21(22):5037-5046. PubMed PMID: 26567363.  

Teh JL, Shah R, La Cava S, et al. Metabotropic glutamate receptor 1 disrupts mammary acinar architecture and initiates malignant transformation of mammary epithelial cells. Breast Cancer Res Treat. 2015;151(1):57-73. PubMed PMID: 25859923.  

Stein MN, Hirshfield KM, Zhong H, Singer EA, Ali SM, Ganesan S. Response to crizotinib in a patient with MET-mutant papillary renal cell cancer after progression on tivantinib. Eur Urol. 2015;67(2):353-354. PubMed PMID: 25457019.  

Joshi S, Tolkunov D, Aviv H, et al. The Genomic Landscape of Renal Oncocytoma Identifies a Metabolic Barrier to Tumorigenesis. Cell Rep. 2015;13(9):1895-1908. PubMed PMID: 26655904.  Link to PubMed:

Hai S, Yong S, Fuyong X, et al. Robust automatic breast cancer staging using a combination of functional genomics and image-omics. Conf Proc IEEE Eng Med Biol Soc. 2015;2015:7226-7229. PubMed PMID: 26737959.  

Tereshchenko IV, Zhong H, Chekmareva MA, et al. ERG and CHD1 heterogeneity in prostate cancer: use of confocal microscopy in assessment of microscopic foci. Prostate. 2014;74(15):1551-1559. PubMed PMID: 25175909.  

Strohecker AM, White E. Targeting mitochondrial metabolism by inhibiting autophagy in BRAF-driven cancers. Cancer Discov. 2014;4(7):766-772. PubMed PMID: 24860158.  

Savla R, Garbuzenko OB, Chen S, Rodriguez-Rodriguez L, Minko T. Tumor-targeted responsive nanoparticle-based systems for magnetic resonance imaging and therapy. Pharm Res. 2014;31(12):3487-3502. PubMed PMID: 24919932.  

Lozy F, Cai-McRae X, Teplova I, et al. ERBB2 overexpression suppresses stress-induced autophagy and renders ERBB2-induced mammary tumorigenesis independent of monoallelic Becn1 loss. Autophagy. 2014;10(4):662-676. PubMed PMID: 24492513.  

Laddha SV, Ganesan S, Chan CS, White E. Mutational landscape of the essential autophagy gene BECN1 in human cancers. Mol Cancer Res. 2014;12(4):485-490. PubMed PMID: 24478461.  

Karsli-Uzunbas G, Guo JY, Price S, et al. Autophagy is required for glucose homeostasis and lung tumor maintenance. Cancer Discov. 2014;4(8):914-927. PubMed PMID: 24875857.  

Hirshfield KM, Ganesan S. Triple-negative breast cancer: molecular subtypes and targeted therapy. Curr Opin Obstet Gynecol. 2014;26(1):34-40. PubMed PMID: 24346128.  

Glod J, Song M, Sharma A, et al. Next generation sequencing as an aid to diagnosis and treatment of an unusual pediatric brain cancer. J Pers Med. 2014;4(3):402-411. PubMed PMID: 25563358.  

Dolfi SC, Jager AV, Medina DJ, Haffty BG, Yang JM, Hirshfield KM. Fulvestrant treatment alters MDM2 protein turnover and sensitivity of human breast carcinoma cells to chemotherapeutic drugs. Cancer Lett. 2014;350(1-2):52-60. PubMed PMID: 24747123.  



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