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Nanjoo Suh, PhD

Selected Publications

Wahler, J., So, J.Y., Kim, Y.C., Liu, F., Maehr, H., Uskokovic, M., and Suh, N., Inhibition of the transition of ductal carcinoma in situ to invasive ductal carcinoma by a Gemini vitamin D analog. Cancer Prev. Res., 7: 617-626, 2014.

Yang, C.S., and Suh, N., Cancer prevention by different forms of tocopherols, Top. Curr. Chem., 329: 21-33, 2013.

So, J.Y., Smolarek, A. K., Salerno, D. M., Maehr, H., Uskokovic, M., Liu, F., and Suh, N., Targeting CD44-STAT3 signaling by Gemini vitamin D analog leads to inhibition of invasion in basal-like breast cancer, PLoS One, 8: e54020, 2013.

Su, Z.Y., Khor, T.O., Shu, L., Lee, J.H., Saw, C. L.-L., Wu, T.-Y., Huang, Y., Suh, N., Yang, C.S., Conney, A.H., Wu, Q., and Kong, A.-N. T., Epigenetic reactivation of Nrf2 in murine prostate cancer TRAMP C1 cells by natural phytochemicals Z-ligustilide and Radix Angelica Sinensis via promoter CpG demethylation, Chem. Res. Tox., 26: 477-485, 2013.

Smolarek, A.K., So, J.Y., Thomas, P.E., Lee, H.J., Paul, S., Dombrowski, A., Wang, C.X., Saw, C. L-L., Khor, T.O., Kong, A.N.T., Reuhl, K., Lee, M.J., Yang, C.S., and Suh, N., Dietary tocopherols inhibit cell proliferation, regulate expression of ERa, PPARg, and Nrf2, and decrease serum inflammatory markers during the development of mammary hyperplasia, Molecular Carcinogenesis, 52: 514-525, 2013.

Maehr, H., Rochel, N., Lee, H.J., Suh, N., and Uskokovic, M., Diastereotopic and Deuterium Effects in Gemini, J. Med. Chem., 56: 3878-3888, 2013.

So, J.Y., Wahler, J., Yoon, T., Smolarek, A. K., Lin, Y., Shih, W.J., Maehr, H., Uskokovic, M., Liby, K., T., Sporn, M.B., and Suh, N., Oral administration of a Gemini vitamin D analog, a triterpenoid and the combination prevents mammary tumorigenesis driven by ErbB2 overexpression, Cancer Prev. Res., 6: 959-970, 2013.

Yang C.S., Suh, N., and Kong, A.-N.T., Does vitamin E prevent or promote cancer?, Can. Prev. Res., 5: 701-5, 2012.

Smolarek, A.K., So, J.Y., Thomas, P.E., Lee, H.J., Paul, S., Dombrowski, A., Wang, C.X., Saw, C. L-L., Khor, T.O., Kong, A.N.T., Reuhl, K., Lee, M.J., Yang, C.S., and Suh, N., Dietary tocopherols inhibit proliferation, regulate expression of nuclear receptors, increase Nrf2 and phase II enzymes, and decrease serum inflammatory markers during the development of mammary hyperplasia, Molecular Carcinogenesis, in press, 2012.

Smolarek, A.K., So, J.Y., Burgess, B., Kong. A.-N.T., Reuhl, K., Lin, Y., Shih, W., Lin, Y., Li, G., Lee, M.J., Chen, Y.-K., Yang, C.S., and Suh, N., Dietary administration of d- and g-tocopherol inhibits tumorigenesis in the animal model of estrogen-receptor positive, but not HER-2 breast cancer, Can. Prev. Res., in press, 2012.

Suh, N., Paul, S., Lee, H.J., Yoon, T., Shah, N., Son, A.I., Reddi, A. H., Medici, D.D., Sporn, M.B., Synthetic triterpenoids, CDDO-Imidazolide and CDDO-Ethyl amide, induce chondrogenesis in calvarial organ cultures, Osteoarthritis Cartilage, 20: 446-450, 2012.

So, J.Y., Lee, H.J., Smolarek, A.K., Paul, S., Wang, C.X., Maehr, H., Uskokovic, M., Zheng, X., Conney, A.H., Cai, L., Liu, F., and Suh, N., A novel Gemini vitamin D represses the expression of a stem cell marker CD44 in breast cancer, Mol. Pharmacol., 79: 360-367, 2011. [PMCID: PMC3061370].

Suh, N., Reddy, B.S., DeCastro, A., Paul, S., Lee, H.J., Smolarek, A.K., So, J.Y., Simi, B., Wang, C.X., Janakiram, N.B., Steele, V. and Rao, C.V., Combination of atorvastatin with sulindac or naproxen profoundly inhibits colonic adenocarcinomas by suppressing the p65/b-catenin/cyclin D1 signaling pathway in rats, Cancer Prev. Res., 4: 1895-1902, 2011. [PMCID: PMC3208056]

Smolarek, A.K., and Suh, N., Chemopreventive activity of vitamin E in breast cancer: A focus on gamma-and delta-tocopherol, Nutrients, 3: 962-986, 2011. [PMCID: PMC3257724]

Lee, H.J., So, J.Y., DeCastro, A., Smolarek, A., Paul, S., Maehr, H., Uskokovic, M., and Suh, N., Gemini vitamin D analog suppresses ErbB2-positive mammary tumor growth via inhibition of ErbB2/AKT/ERK signaling, J. Steroid Biochem. Mol. Biol., 121: 408-412, 2010. [PMCID: PMC2906695]

Paul, S., DeCastro, A., Lee, H.J., Smolarek, A.K., So, J.Y., Simi, B., Wang, C.X., Zhou, R., Rimando, A.M., and Suh, N., Dietary intake of pterostilbene, a constituent of blueberries, inhibits the b-catenin/p65 downstream signaling pathway and colon carcinogenesis in rats, Carcinogenesis, 31: 1272-1278, 2010. [PMCID: PMC2899944].

Lee, H.J., Ju, J., Paul, S., So, J.Y., DeCastro, A., Smolarek, A.K., Lee, M.-J., Yang, C.S., Newmark, H.L., and Suh, N., Mixed tocopherols prevent mammary tumorigenesis by inhibiting estrogen action and activating PPAR-g, Clin. Can. Res., 15: 4242-4249, 2009. [PMCID: PMC2753525]

Lee, H.J., Paul, S., Atalla, N., Thomas, P.E., Lin, J., Yang, I., Buckley, B.T., Lu, G., Zheng, X., Lou, Y.-R., Conney, A. H., Maehr, H., Adorini, L., Uskokovic, M., and Suh, N., Gemini vitamin D analogs inhibit estrogen receptor positive and estrogen receptor negative mammary tumorigenesis without hypercalcemic toxicity, Cancer Prev. Res., 1: 476-484, 2008. [PMCID: PMC2753526]

Suh, N., Paul, S., Hao X., Simi, B., Xiao, H., Rimando, A.M., and Reddy, B.S., Pterostilbene, an active constituent of blueberries, suppresses aberrant crypt foci formation in the azoxymethane-induced colon carcinogenesis model in rats, Clin. Cancer Res., 13:350-355, 2007.

Lee, H.J., Ji, Y., Paul, S., Maehr, H., Uskokovic, M., and Suh, N., Activation of bone morphogenetic protein signaling by a Gemini vitamin D3 analog is mediated by Ras/protein kinase Ca, Cancer Res., 67: 11840-11847, 2007.

Suh, N., Paul, S., Lee, H.J., Ji, Y., Lee, M.-J., Yang, C.S., Reddy, B.S., and Newmark, H.L., Mixed tocopherols inhibit N-methyl-N-nitrosourea induced mammary tumor growth in rats, Nutr. Cancer, 59: 76-81, 2007.

Suh, N., Roberts, A.B., Birkey Reffey S., Miyazono, K., Itoh, S., ten Dijke, P., Heiss, E.H., Place, A.E., Risingsong, R., Williams, C.R., Honda, T., Gribble, G.W., Sporn, M.B., Synthetic triterpenoids enhance TGF-b/Smad signaling, Cancer Res., 63: 1371-1376, 2003.