Researcher Profile

X. F. Steven Zheng, PhD

Co-Leader, Cancer Pharmacology and Preclinical Therapeutics Research Program at the Rutgers Cancer Institute of New Jersey
University Professor of Pharmacology
Robert Wood Johnson Medical School
Rutgers, The State University of New Jersey

RWJMS Research Tower
675 Hoes Lane West, Room 142
Piscataway, NJ 08854

Phone: (732) 235-2894
Email: zhengst@rwjms.rutgers.edu

Assistant: Laura Rossano
(732) 235-7066
Email: lr516@rutgers.edu

Research Program Alignments

Membership Type: Full


Research Interests

  • Growth is the process whereby cells accumulate mass, which determines the sizes of cells, organs and organisms. Deregulation of growth is directly linked to human diseases from cancer to aging. Specifically, our current focus is on the target of rapamycin (TOR) protein, a highly conserved phosphatidylinositol kinase-related kinase (PIKK) and a central controller of cell growth. We are interested in dissecting the basic signal transduction mechanisms by TOR and in understanding the mechanisms by which cancer cells resist rapamycin and rapamycin analogs. We hope to ultimately develop more effective therapeutics against human cancer.

The content for this Research Profile is maintained by Paul Novembre (novembre@cinj.rutgers.edu)