John Glod, MD, PhD
Assistant Professor of Pediatrics and Pharmacology
Cancer Institute of New Jersey
Phone: (732) 235-5437
Assistant: Susan Christ
Research Program Alignment
Membership Type: Full
- Tumor Microenvironment
- Mesenchymal Stromal Cell
- Stromal-Derived Factor 1
Ferrari, N, Glod, J., Lee, J., Kobiler, D., and Fine H.A., (2003) Bone Marrow-derived, Endothelial Progenitor-like Cells as Angiogenesis-Selective Gene Targeting Vectors. Gene Therapy 10(8):647-56.
Anderson, SA, Glod, J, Arbab, AS, Noel, M, Ashari, P, Fine, HA, and Frank, JA. (2005) Non-Invasive MR Imaging of Magnetically Labeled Stem Cells to Directly Identify Neovasculature in a Glioma Model. Blood. 105(1):420-5.
Glod, J, Kobiler D, Noel M, Koneru R, Lehrer S, Medina D, Maric D, and Fine HA, (2006) Monocytes form a vascular barrier and participate in vessel repair after brain injury, Blood. 107(3):940-46.
Menon LG, Picinich S, Koneru R, Gao H, Lin SY, Koneru M, Mayer-Kuckuk P, Glod J, and Banerjee D. (2007) Differential Gene Expression Associated with Migration of Mesenchymal Stem Cells to Conditioned Medium From Tumor Cells or Bone Marrow Cells. Stem Cells. 25: 520-528.
Cole PD, Drachtman RA, Masterson M, Smith AK, Glod J, Zebala JA, Lisi S, Drapala DA, and Kamen BA. (2008) Phase 2B Trial of Aminopterin in Multiagent Therapy for Children with newly Diagnosed Acute Lymphoblastic Leukemia. Cancer Chemotherapy and Pharmacology, 62(1): 65-75.
Jan B. Wollack, Benedette Makori, Stuti Ahlawat, Rajeth Koneru, Sonia Picinich, Angela Smith, I. David Goldman, Andong Qiu, Peter D. Cole, John Glod, and Barton Kamen. (2008) Characterization of folate uptake by choroid plexus epithelial cells in a rat primary culture model. Journal of Neurochemistry. 104(6): 1494-503.
Mishra PJ, Mishra PJ, Humeniuk R, Medina, D, Alexe G, Mesirov JP, Ganesan S, Glod J, and Banerjee D. (2008) Carcinoma-associated fibroblast-like differentiation of human mesenchymal stem cells. Cancer Research 68(11):4331-39.
Siang-Yo Lin , Jun Yang, Allen D. Everett, Charles V. Clevenger, Mythili Koneru, Barton Kamen, Debabrata Banerjee, and John Glod (2008). The isolation of novel mesenchymal stromal cell chemotactic factors from the conditioned medium of tumor cells. Experimental Cell Research 15;314(17):3107-17.
Gao H., Priebe W., Glod J., and Banerjee D. (2009). Activation of signal transducers and activators of transcription 3 and focal adhesion kinase by stromal cell-derived factor 1 is required for migration of human mesenchymal stem cells in response to tumor cell-conditioned medium. Stem Cells 27(4): 857-65.
Picinich SC, Glod JW, and Banerjee D. (2010) Protein Kinase C zeta regulates interleukin-8-mediated stromal-derived factor-1 expression and migration of human mesenchymal stromal cells. Experimental Cell Research. 316(4):593-602.
Rattigan Y, Hsu JM, Mishra PJ, Glod J, and Banerjee D. (2010) Interleukin 6 mediated recruitment of mesenchymal stem cells to the hypoxic tumor milieu. Experimental Cell Research. 316(20):3417-24.
Rajeth Koneru, David Kobiler, Shoshona Lehrer, Jiadong Li, Nico van Rooijen, Debabrata Banerjee, and John Glod. (2011) Macrophages Play a Key Role in early Blood Brain Barrier Reformation after Hypothermic Brain Injury. Neuroscience Letters, 501(3):148-51.
Rattigan YI, Patel BB, Ackerstaff E, Sukenick G, Koutcher JA, Glod JW, Banerjee D. Lactate is a mediator of metabolic cooperation between stromal carcinoma associated fibroblasts and glycolytic tumor cells in the tumor microenvironment. Exp Cell Res. 2011 Dec 8. [Epub ahead of print].
Medina D, Goodell L, Glod J, Gelinas C, Rabson A, and Strair R., Mesenchymal stromal cells protect mantle cell lymphoma cells from spontaneous and drug-induced apoptosis through secretion of B-cell activating factor and activation of the canonical and non-canonical nuclear factor kB pathways. Hematologica. Feb 2012. [Epub ahead of print] PMID 22371181.
Anton K, Banerjee D, Glod J. Macrophage-associated mesenchymal stem cells assume an activated, migratory, pro-inflammatory phenotype with increased IL-6 and CXCL10 secretion. PLoS One. Epub Apr 2012; 7(4):e35036.