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Paola Leone, PhD

Publications since 2011

Zaroff, S. Leone, P. Markov, V. Francis, J. S. Transcriptional regulation of N-acetylaspartate metabolism in the 5xFAD model of Alzheimer's disease: Evidence for neuron-glia communication during energetic crisis. Mol Cell Neurosci, In process, . (PMID: 25766789)

Gautier, E. L. Ivanov, S. Williams, J. W. Huang, S. C. Marcelin, G. Fairfax, K. Wang, P. L. Francis, J. S. Leone, P. Wilson, D. B. Artyomov, M. N. Pearce, E. J. Randolph, G. J. Gata6 regulates aspartoacylase expression in resident peritoneal macrophages and controls their survival. J Exp Med, 211:1525-1531, . (PMID: 25024137, PMCID: PMC4113942)

Francis, J. S. Markov, V. Leone, P. Dietary triheptanoin rescues oligodendrocyte loss, dysmyelination and motor function in the nur7 mouse model of Canavan disease. J Inherit Metab Dis, 37:369-381, . (PMID: 24288037)

Janson, C. G. Romanova, L. G. Leone, P. Nan, Z. Belur, L. McIvor, R. S. Low, W. Comparison of Endovascular and Intraventricular Gene Therapy With Adeno-Associated Virus-alpha-L-Iduronidase for Hurler Disease. Neurosurgery, 74:99-111, . (PMID: 24077583, PMCID: PMC4116107)

Kantor, B. McCown, T. Leone, P. Gray, S. J. Clinical applications involving CNS gene transfer. Adv Genet, 87:71-124, . (PMID: 25311921)

Assadi, M. Wang, D. J. Velazquez-Rodriquez, Y. Leone, P. Multi-Voxel 1H-MRS in Metachromatic Leukodystrophy. J Cent Nerv Syst Dis, 5:25-30, . (PMID: 23926443, PMCID: PMC3728201)

Leone, P. Shera, D. McPhee, S. W. Francis, J. S. Kolodny, E. H. Bilaniuk, L. T. Wang, D. J. Assadi, M. Goldfarb, O. Goldman, H. W. Freese, A. Young, D. During, M. J. Samulski, R. J. Janson, C. G. Long-term follow-up after gene therapy for canavan disease. Sci Transl Med, 4:165ra163, . (PMID: 23253610, PMCID: PMC3794457)

Francis, J. S. Strande, L. Markov, V. Leone, P. Aspartoacylase supports oxidative energy metabolism during myelination. J Cereb Blood Flow Metab, 32:1725-1736, . (PMID: 22617649, PMCID: PMC3434629)

Assadi, M. Wang, D. J. Anderson, K. Carran, M. Bilaniuk, L. Leone, P. Vitamin k antagonist warfarin for palliative treatment of metachromatic leukodystrophy, a compassionate study of four subjects. J Cent Nerv Syst Dis, 4:73-79, . (PMID: 23650469, PMCID: PMC3619661)

Francis, J. S. Strande, L. Pu, A. Leone, P. Endogenous aspartoacylase expression is responsive to glutamatergic activity in vitro and in vivo. Glia, 59:1435-1446, . (PMID: 21608034)