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Raymond B. Birge, PhD

Publications since 2011

Kumar, S. Lu, B. Dixit, U. Hossain, S. Liu, Y. Li, J. Hornbeck, P. Zheng, W. Sowalsky, A. G. Kotula, L. Birge, R. B. Reciprocal regulation of Abl kinase by Crk Y251 and Abi1 controls invasive phenotypes in glioblastoma. Oncotarget, In process, . (PMID: 26473374)

Sriram, G. Jankowski, W. Kasikara, C. Reichman, C. Saleh, T. Nguyen, K. Q. Li, J. Hornbeck, P. Machida, K. Liu, T. Li, H. Kalodimos, C. G. Birge, R. B. Iterative tyrosine phosphorylation controls non-canonical domain utilization in Crk. Oncogene, In process, . (PMID: 25381819)

Nguyen, K. Q. Tsou, W. I. Calarese, D. A. Kimani, S. G. Singh, S. Hsieh, S. Liu, Y. Lu, B. Wu, Y. Garforth, S. J. Almo, S. C. Kotenko, S. V. Birge, R. B. Overexpression of MERTK Receptor Tyrosine Kinase in Epithelial Cancer Cells Drives Efferocytosis in a Gain-of-Function Capacity. J Biol Chem, 289:25737-25749, . (PMID: 25074939, PMCID: PMC4162176)

Tsou, W. I. Nguyen, K. Q. Calarese, D. A. Garforth, S. J. Antes, A. L. Smirnov, S. V. Almo, S. C. Birge, R. B. Kotenko, S. V. Receptor Tyrosine Kinases, TYRO3, AXL and MER, Demonstrate Distinct Patterns and Complex Regulation of Ligand-Induced Activation. J Biol Chem, 289:25750-25763, . (PMID: 25074926, PMCID: PMC4162177)

Kumar, S. Fajardo, J. E. Birge, R. B. Sriram, G. Crk at the Quarter Century Mark: Perspectives in Signaling and Cancer. J Cell Biochem, 115:819-825, . (PMID: 24356912)

Yang, A. Dai, J. Xie, Z. Colman, R. W. Wu, Q. Birge, R. B. Wu, Y. High molecular weight kininogen binds phosphatidylserine and opsonizes urokinase plasminogen activator receptor-mediated efferocytosis. J Immunol, 192:4398-4408, . (PMID: 24688027, PMCID: PMC4134950)

Kimani, S. G. Geng, K. Kasikara, C. Kumar, S. Sriram, G. Wu, Y. Birge, R. B. Contribution of Defective PS Recognition and Efferocytosis to Chronic Inflammation and Autoimmunity. Front Immunol, 5:566, . (PMID: 25426118, PMCID: PMC4226236)

Nguyen, K. Q. Tsou, W. I. Kotenko, S. Birge, R. B. TAM receptors in apoptotic cell clearance, autoimmunity, and cancer. Autoimmunity, 46:294-297, . (PMID: 23662598)

Teplova, I. Lozy, F. Price, S. Singh, S. Barnard, N. Cardiff, R. D. Birge, R. B. Karantza, V. ATG proteins mediate efferocytosis and suppress inflammation in mammary involution. Autophagy, 9:459-475, . (PMID: 23380905, PMCID: PMC3627664)

Sriram, G. Birge, R. B. Commentary: The carboxyl-terminal Crk SH3 domain: Regulatory strategies and new perspectives. FEBS Lett, 586:2615-2618, . (PMID: 22710158)

Jankowski, W. Saleh, T. Pai, M. T. Sriram, G. Birge, R. B. Kalodimos, C. G. Domain organization differences explain Bcr-Abl's preference for CrkL over CrkII. Nat Chem Biol, 8:590-596, . (PMID: 22581121, PMCID: PMC3423979)

Hossain, S. Dubielecka, P. M. Sikorski, A. F. Birge, R. B. Kotula, L. Crk and ABI1: binary molecular switches that regulate abl tyrosine kinase and signaling to the cytoskeleton. Genes Cancer, 3:402-413, . (PMID: 23226578, PMCID: PMC3513786)

Birge, R. B. Monographs editor. Genes Cancer, 3:331, . (PMID: 23226570, PMCID: PMC3513797)

Ucker, D. S. Jain, M. R. Pattabiraman, G. Palasiewicz, K. Birge, R. B. Li, H. Externalized glycolytic enzymes are novel, conserved, and early biomarkers of apoptosis. J Biol Chem, 287:10325-10343, . (PMID: 22262862, PMCID: PMC3323007)

Sriram, G. Reichman, C. Tunceroglu, A. Kaushal, N. Saleh, T. Machida, K. Mayer, B. Ge, Q. Li, J. Hornbeck, P. Kalodimos, C. G. Birge, R. B. Phosphorylation of Crk on tyrosine 251 in the RT loop of the SH3C domain promotes Abl kinase transactivation. Oncogene, 30:4645-4655, . (PMID: 21602891, PMCID: PMC3311107)

Marfe, G. Di Stefano, C. Gambacurta, A. Ottone, T. Martini, V. Abruzzese, E. Mologni, L. Sinibaldi-Salimei, P. de Fabritis, P. Gambacorti-Passerini, C. Amadori, S. Birge, R. B. Sphingosine kinase 1 overexpression is regulated by signaling through PI3K, AKT2, and mTOR in imatinib-resistant chronic myeloid leukemia cells. Exp Hematol, 39:653-665.e6, . (PMID: 21392556)

Sarkar, P. Saleh, T. Tzeng, S. R. Birge, R. B. Kalodimos, C. G. Structural basis for regulation of the Crk signaling protein by a proline switch. Nat Chem Biol, 7:51-57, . (PMID: 21131971, PMCID: PMC3039521)