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Howard L. Kaufman, MD, FACS

Publications since 2011

Andtbacka, R. H. Kaufman, H. L. Collichio, F. Amatruda, T. Senzer, N. Chesney, J. Delman, K. A. Spitler, L. E. Puzanov, I. Agarwala, S. S. Milhem, M. Cranmer, L. Curti, B. Lewis, K. Ross, M. Guthrie, T. Linette, G. P. Daniels, G. A. Harrington, K. Middleton, M. R. Miller, W. H. Jr Zager, J. S. Ye, Y. Yao, B. Li, A. Doleman, S. VanderWalde, A. Gansert, J. Coffin, R. Talimogene Laherparepvec Improves Durable Response Rate in Patients With Advanced Melanoma. J Clin Oncol, In process, . (PMID: 26014293)

Hughes, T. Klairmont, M. Broucek, J. Iodice, G. Basu, S. Kaufman, H. L. The prognostic significance of stable disease following high-dose interleukin-2 (IL-2) treatment in patients with metastatic melanoma and renal cell carcinoma. Cancer Immunol Immunother, 64:459-465, . (PMID: 25603775, PMCID: PMC4448124)

Dharmadhikari, N. Mehnert, J. M. Kaufman, H. L. Oncolytic virus immunotherapy for melanoma. Curr Treat Options Oncol, 16:326, . (PMID: 25777572)

de Vries, C. R. Kaufman, H. L. Lattime, E. C. Oncolytic viruses: focusing on the tumor microenvironment. Cancer Gene Ther, In process, . (PMID: 25721204)

Goldufsky, J. Wood, S. Hajihossainlou, B. Rehman, T. Majdobeh, O. Kaufman, H. L. Ruby, C. E. Shafikhani, S. H. Pseudomonas aeruginosa exotoxin T induces potent cytotoxicity against a variety of murine and human cancer cell lines. J Med Microbiol, 64:164-173, . (PMID: 25627204)

Kaufman, H. L. Precision Immunology: The Promise of Immunotherapy for the Treatment of Cancer. J Clin Oncol, In process, . (PMID: 25605852)

Goldufsky, J. Wood, S. Hajihossainlou, B. Rehman, T. Majdobeh, O. Kaufman, H. L. Ruby, C. E. Shafikhani, S. H. Pseudomonas aeruginosa Exotoxin T induces potent cytotoxicity against a variety of murine and human cancer cell lines. J Med Microbiol, In process, . (PMID: 25587079)

Kohlhapp, F. J. Broucek, J. R. Hughes, T. Huelsmann, E. J. Lusciks, J. Zayas, J. P. Dolubizno, H. Fleetwood, V. A. Grin, A. Hill, G. E. Poshepny, J. L. Nabatiyan, A. Ruby, C. E. Snook, J. D. Rudra, J. S. Schenkel, J. M. Masopust, D. Zloza, A. Kaufman, H. L. NK cells and CD8+ T cells cooperate to improve therapeutic responses in melanoma treated with interleukin-2 (IL-2) and CTLA-4 blockade. J Immunother Cancer, 3:18, . (PMID: 25992289, PMCID: PMC4437746)

Zloza, A. Kim, D. W. Broucek, J. Schenkel, J. M. Kaufman, H. L. High-Dose IL-2 Induces Rapid Albumin Uptake by Endothelial Cells Through Src-Dependent Caveolae-Mediated Endocytosis. J Interferon Cytokine Res, 34:915-919, . (PMID: 24963699, PMCID: PMC4217041)

Lu, R. Wu, S. Zhang, Y. Xia, Y. Huelsmann, E. J. Lacek, A. T. Nabatiyan, A. Richards, M. H. Narasipura, S. D. Lutgen, V. Chen, H. Kaufman, H. L. Chen, D. Al-Harthi, L. Zloza, A. Sun, J. HIV Infection Accelerates Gastrointestinal Tumor Outgrowth in NSG-HuPBL Mice. AIDS Res Hum Retroviruses, 30:677-684, . (PMID: 24593860, PMCID: PMC4076996)

Kaufman, H. L. Kim, D. W. Kim-Schulze, S. Deraffele, G. Joagoda, M. C. Broucek, J. Zloza, A. Results of a Randomized Phase I Gene Therapy Clinical Trial of Non-oncolytic Fowlpox Viruses Encoding T cell Co-stimulatory Molecules. Hum Gene Ther, 25:452-460, . (PMID: 24484178, PMCID: PMC4027985)

Kaufman, H. L. Melanoma as a model for precision medicine in oncology. Lancet Oncol, 15:251-253, . (PMID: 24508105)

Zloza, A. Kim, D. W. Kim-Schulze, S. Jagoda, M. C. Monsurro, V. Marincola, F. M. Kaufman, H. L. Immunoglobulin-like transcript 2 (ILT2) is a biomarker of therapeutic response to oncolytic immunotherapy with vaccinia viruses. J Immunother Cancer, 2:1, . (PMID: 24829758, PMCID: PMC4019911)

Kim, D. W. Zloza, A. Broucek, J. Schenkel, J. M. Ruby, C. Samaha, G. Kaufman, H. L. Interleukin-2 alters distribution of CD144 (VE-cadherin) in endothelial cells. J Transl Med, 12:113, . (PMID: 24885155, PMCID: PMC4062649)

Kaufman, H. L. Ruby, C. E. Hughes, T. Slingluff, C. L. Jr Current status of granulocyte-macrophage colony-stimulating factor in the immunotherapy of melanoma. J Immunother Cancer, 2:11, . (PMID: 24971166, PMCID: PMC4072479)

Wong, M. K. Kaufman, H. L. Daniels, G. A. McDermott, D. F. Aung, S. Lowder, J. N. Morse, M. A. Implementation of an Interleukin-2 National Registry: an opportunity to improve cancer outcomes. J Immunother Cancer, 2:20, . (PMID: 25031835, PMCID: PMC4100489)

Kaufman, H. L. Wong, M. K. Daniels, G. A. McDermott, D. F. Aung, S. Lowder, J. N. Morse, M. A. The Use of Registries to Improve Cancer Treatment: A National Database for Patients Treated with Interleukin-2 (IL-2). J Pers Med, 4:52-64, . (PMID: 25562142)

Kaufman, H. L. Kirkwood, J. M. Hodi, F. S. Agarwala, S. Amatruda, T. Bines, S. D. Clark, J. I. Curti, B. Ernstoff, M. S. Gajewski, T. Gonzalez, R. Hyde, L. J. Lawson, D. Lotze, M. Lutzky, J. Margolin, K. McDermott, D. F. Morton, D. Pavlick, A. Richards, J. M. Sharfman, W. Sondak, V. K. Sosman, J. Steel, S. Tarhini, A. Thompson, J. A. Titze, J. Urba, W. White, R. Atkins, M. B. The Society for Immunotherapy of Cancer consensus statement on tumour immunotherapy for the treatment of cutaneous melanoma. Nat Rev Clin Oncol, 10:588-598, . (PMID: 23982524)

Mosenson, J. A. Zloza, A. Nieland, J. D. Garrett-Mayer, E. Eby, J. M. Huelsmann, E. J. Kumar, P. Denman, C. J. Lacek, A. T. Kohlhapp, F. J. Alamiri, A. Hughes, T. Bines, S. D. Kaufman, H. L. Overbeck, A. Mehrotra, S. Hernandez, C. Nishimura, M. I. Guevara-Patino, J. A. Le Poole, I. C. Mutant HSP70 reverses autoimmune depigmentation in vitiligo. Sci Transl Med, 5:174ra28, . (PMID: 23447019, PMCID: PMC3912753)