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Bozena (Bo) B. Michniak-Kohn, PhD, MRPharmS

Selected Publications

Chronological order (Total 120 papers, 33 books & book chapters).

  1. Song, Y., Xiao, C. Mendelsohn, R., Zheng, T., Strekowski, L., Michniak, B. Investigation of iminosulfuranes as novel penetration enhancers: enhancement activity and cytotoxicity. Pharm. Res. (2005) 22 (11), 1918-25. PMID 16132348.
  2. Pensack, R.D., Michniak, B.B., Moore, D., Mendelsohn, R. I.R. kinetic/structural studies of barrier reformation in intact stratum corneum following thermal perturbation. Applied Spectroscopy (2006) 60 (12), 1399-1404.PMID 17217589.
  3. Thakur, R., Meidan, V., Michniak, B. Transdermal and buccal delivery of methylxanthines through human tissue in vitro. Drug Develop. & Ind. Pharmacy (2007), 33, 513-521. PMID 17520442.
  4. Sheihet, L., Chandra, P., Batheja, P., Devore, D., Kohn, J., Michniak, B. Tyrosine-derived nanospheres for enhanced topical skin penetration. Int. J. Pharmaceutics, (2008) 350, 312-319. PMID 17897801.
  5. Sintov, A.C., Zhang, P., Michniak-Kohn, B.B. Cutaneous biotransformation of N-(4-bromobenzoyl)-S,S-dimethyliminosulfurane and its product, 4-bromobenzamide,  leading to percutaneous penetration enhancement of drugs: initial evidence using hydrocortisone. J. Controlled Release, (2009), 133, 44-51. PMID 18950667.
  6. Batheja, P., Song, Y., Wertz, P., Michniak-Kohn, B. Effects of growth conditions on the barrier properties of a human skin equivalent. Pharm. Research (2009), 26 (7), 1689-1700. PMID 19415472.
  7. Kaushik, D., Costache, A., Michniak-Kohn, B. Percutaneous penetration modifiers and formulation effects:  Part I. International J. of Pharmaceutics (2010), 386,42-51. PMID 19900521.
  8. Kaushik, D., Costache, A., Michniak-Kohn, B. Percutaneous penetration modifiers and formulation effects: Thermal and Spectral Analyses. AAPS Pharm Sci. Tech. (2010), 11 (3), 1068-1083. PMID 20582492.
  9. Batheja, P. Sheihet, L., Kohn, J., Singer, A., Michniak-Kohn, B. Topical drug delivery by a polymeric nanosphere gel: formulation optimization and in vitro and in vivo distribution studies. Journal of Controlled Release, (2011), 149, 159-167 & doi:10.1016/j/jconrel.2010.10.005.  PMID 20950659.
  10. Hu, L., Michniak-Kohn, B. Enhanced in vitro transbuccal drug delivery of ondansetron HCl. International J. of Pharmaceutics, (2011), 404, 66-74 & doi:10.1016/j.ijpharm. 2010.10.052. PMID 21056647.
  11. Hu, L., Silva, S.M.C., Damaj, B.B., Martin, R., Michniak-Kohn, B.B. Transdermal and transbuccal drug delivery systems: Enhancement using iontophoretic and chemical approaches. Int. J. Pharm., (2011), 421, 53-62 and doi: 10.1016/j.ijpharm.2010.10.052. PMID 21963468.
  12. Zhang, J., Michniak-Kohn, B. Investigation of microemulsion microstructures and their relationship to transdermal permeation of model drugs: ketoprofen, lidocaine and caffeine. Int. J. Pharm. (2011), 421, 34-44. PMID 21959104.
  13. Silva, S.M.C., Hu, L. Sousa, J.J.S., Pais, A.A.C.C., Michniak-Kohn, B. A combination of nonionic surfactants and iontophoresis to enhance the transdermal drug delivery of ondrasetron HCl and diltiazem HCl.  European Journal of Pharmaceutics and Biopharmaceutics (2011), doi: 10.1016/j.ejpb.2011.11.010. PMID 22137964.
  14. Ghosh, I., Michniak-Kohn, B. A comparative study of Vitamin E TPGS/HPMC supersaturated system and other solubilizer/ polymer combinations to enhance the permeability of a poorly soluble drug through the skin. Drug Development & Industrial Pharmacy (2012), doi:10.3109/03639045.2011.653363. PMID 22296239.
  15. Susarla, R., Sievens-Figueroa, L., Bhakay, A., Shen, Y., Jerez-Rozo, J. L., Engen, W., Khusid, B., Biligili, E., Romanach, R., Morris, K.R., Michniak-Kohn, B., Dave, R. N. Fast drying of biocompatible polymer films loaded with poorly water soluble drugs nano-particles via low temperature forced convection. Int. J. Pharm. (2013), 445, 93-103. PMID 23911341.
  16. Ghosh, I., Michniak-Kohn, B. Influence of critical parameters of nanosuspension formulation on the permeability of a poorly soluble drug through the skin-A case Study. AAPS- Pharm. Tech. (2013), doi: 10:1208/s12249-013-9995-4. PMID 23824877.
  17. Silva, S. M.C., Sousa, J. J. S., Marques, E., Pais, A.A.C.C., Michniak-Kohn, B.B. Structure activity relationships in alkylammonium C12-gemini surfactants used as dermal enhancers. AAPS Journal, 2013, DOI: 10.1208/s12248-013-9518-y. Published on line 20 August 2013.  PMID 23959685.