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Debra L. Laskin, PhD

Selected Publications

Fakhrzadeh, L., Laskin, J.D., and Laskin, D.L. (2008). Regulation of caveolin-1 expression, nitric oxide production and oxidant-induced tissue injury by tumor necrosis factor-alpha following ozone inhalation. Toxicology and Applied Pharmacology, 227: 380-389.

Chen, L.C., Gordon, M., Laskin, J.D., and Laskin, D.L. (2008). Regulation of TREM   expression in hepatic macrophages and endothelial cells during acute endotoxemia. Experimental and Molecular Pathology, 84:145-155.

Weinberger, B., Vetrano, A., Laskin, J.D., and Laskin, D.L. (2008). Mechanisms mediating reduced responsiveness of neonatal neutrophils to lipoxin A4. Pediatric Research, 64: 393-398.

Gardner, C.R., Gray, J.P., Joseph, L.B., Cervelli, J., Bremer, N., Kim, Y., Mishin, V., Laskin, J.D., and Laskin, D.L. (2010). Potential role of caveolin-1 in acetaminophen-induced hepatotoxicity. Toxicology and Applied Pharmacology, 245: 36-46.

Wang, Y., Gray, J.P, Mishin, V., Heck, D.E., Laskin, D.L., and Laskin, J.D. (2010). Distinct roles of cytochrome P450 reductase in mitomycin c redox cycling and cytotoxicity. Molecular Cancer Therapeutics, 9: 1852-1863. 

Vetrano, A.M., Laskin, D.L., Archer, F., Syed K., Gray, J.P., Laskin, J.D., Nwebube, N., and Weinberger, B. (2010). Inflammatory effects of phthalates in neonatal neutrophils. Pediatric Research, 68: 134-139.

Laskin, D.L., Chen, L., Hankey, P.A., and Laskin, J.D. (2010). Role of STK in mouse liver macrophage and endothelial cell responsiveness during acute endotoxemia. Journal of Leukocyte Biology. 88: 373-382.

Malaviya, R., Sunil, V.R., Cervelli, J., Anderson, D.R., Holmes, W.W., Conti, M.L., Gordon, R.E., Laskin, J.D., and Laskin, D.L. (2010). Inflammatory effects of inhaled sulfur mustard in rat lung. Toxicology and Applied Pharmacology, 248: 89-99.

Laskin, D.L., Sunil, V.R., and Laskin, J.D. (2011). Macrophages and tissue Injury: agents of defense or destruction? Annual Review of Pharmacology and Toxicology, 51, 267-288.

Sunil, V.R., Patel-Vayas, K., Shen, J., Gow, A.J., Laskin, J.D., and Laskin, D.L. (2011). Role of TNFR1 in lung injury and altered lung function induced by the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfide. Toxicology and Applied Pharmacology, 250: 245-255.

Dragomir A.C., Laskin, J.D., and Laskin, D.L. (2011). Macrophage activation by factors released from acetaminophen-injured hepatocytes: Potential role of HMGB1. Toxicology and Applied Pharmacology, 253: 170-177.

Connors, A., Laskin, J.D., Laskin, D.L. (2012). Ozone-induced lung Injury and sterile inflammation. Role of toll-like receptor 4. Experimental and Molecular Pathology, 92: 229-235.

Dragomir, A., Laskin, J.D., Laskin, D.L. (2012). Role of galectin-3 in acetaminophen-induced hepatotoxicity and inflammatory mediator production. Toxicological Sciences, 127:609-619.

Gardner, C.R., Mishin, V., Hankey, P., Laskin, J.D., Laskin, D.L. (2012). Regulation of alternative macrophage activation in the liver following acetaminophen intoxication by stem cell-derived tyrosine kinase. Toxicology and Applied Pharmacology, 262:139-148.

Sunil, V.R., Shen, J., Patel-Vayas, K., Gow, A.J., Laskin, J.D., Laskin, D.L. (2012). Role of reactive nitrogen species generated via inducible nitric oxide synthase in vesicant-induced lung injury, inflammation and altered lung functioning. Toxicology and Applied Pharmacology, 26: 22-30.