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Nan Gao, PhD

Publications since 2011

Zhang, X. Gao, N. RAB and RHO GTPases regulate intestinal crypt cell homeostasis and enterocyte function. Small GTPases, In process, . (PMID: 27142493)

Mahon, M. Xu, J. Yi, X. Liu, X. Gao, N. Zhang, L. Paneth Cell in Adenomas of the Distal Colorectum Is Inversely Associated with Synchronous Advanced Adenoma and Carcinoma. Sci Rep, 6:26129, . (PMID: 27188450)

Sakamori, R. Zhang, L. Gao, N. Plasmalemma Vesicle Associated Protein Truncation Causes Lethal Protein-Losing Enteropathy in Humans. Cell Mol Gastroenterol Hepatol, 1:348-349, . (PMID: 26225357, PMCID: PMC4516028)

Patel, C. R. Douard, V. Yu, S. Tharabenjasin, P. Gao, N. Ferraris, R. P. Fructose-induced increases in expression of intestinal fructolytic and gluconeogenic genes are regulated by GLUT5 and KHK. Am J Physiol Regul Integr Comp Physiol, In process, . (PMID: 26084694)

Patel, C. Douard, V. Yu, S. Gao, N. Ferraris, R. P. Transport, metabolism, and endosomal trafficking-dependent regulation of intestinal fructose absorption. FASEB J, In process, . (PMID: 26071406)

Das, S. Yu, S. Sakamori, R. Vedula, P. Feng, Q. Flores, J. Hoffman, A. Fu, J. Stypulkowski, E. Rodriguez, A. Dobrowolski, R. Harada, A. Hsu, W. Bonder, E. M. Verzi, M. P. Gao, N. Rab8a vesicles regulate Wnt ligand delivery and Paneth cell maturation at the intestinal stem cell niche. Development, In process, . (PMID: 26015543)

Yu, S. Gao, N. Compartmentalizing intestinal epithelial cell toll-like receptors for immune surveillance. Cell Mol Life Sci, In process, . (PMID: 26001904)

Knowles, B. C. Weis, V. G. Yu, S. Roland, J. T. Williams, J. A. Alvarado, G. S. Lapierre, L. A. Shub, M. D. Gao, N. Goldenring, J. R. Rab11a regulates syntaxin 3 localization and microvillus assembly in enterocytes. J Cell Sci, 128:1617-1626, . (PMID: 25673875)

Yu, D. H. Gadkari, M. Zhou, Q. Yu, S. Gao, N. Guan, Y. Schady, D. Roshan, T. N. Chen, M. H. Laritsky, E. Ge, Z. Wang, H. Chen, R. Westwater, C. Bry, L. Waterland, R. A. Moriarty, C. Hwang, C. Swennes, A. G. Moore, S. R. Shen, L. Postnatal epigenetic regulation of intestinal stem cells requires DNA methylation and is guided by the microbiome. Genome Biol, 16:211, . (PMID: 26420038, PMCID: PMC4589031)

Yu, S. Yehia, G. Wang, J. Stypulkowski, E. Sakamori, R. Jiang, P. Hernandez-Enriquez, E. B. Tran, T. S. Bonder, E. M. Guo, W. Gao, N. Global Ablation of Mouse Rab11a Impairs Early Embryogenesis and Matrix Metalloproteinase Secretion. J Biol Chem, 289:32030-32043, . (PMID: 25271168, PMCID: PMC4231680)

Feng, Q. Gao, N. Keeping Wnt Signalosome in Check by Vesicular Traffic. J Cell Physiol, In process, . (PMID: 25336320)

Sakamori, R. Yu, S. Zhang, X. Hoffman, A. Sun, J. Das, S. Vedula, P. Li, G. Fu, J. Walker, F. Yang, C. S. Yi, Z. Hsu, W. Yu, D. H. Shen, L. Rodriguez, A. J. Taketo, M. M. Bonder, E. M. Verzi, M. P. Gao, N. CDC42 inhibition suppresses progression of incipient intestinal tumors. Cancer Res, 74:5480-5492, . (PMID: 25113996, PMCID: PMC4184946)

Chahar, S. Gandhi, V. Yu, S. Desai, K. Cowper-Sal Lari, R. Kim, Y. Perekatt, A. O. Kumar, N. Thackray, J. K. Musolf, A. Kumar, N. Hoffman, A. Londono, D. Vazquez, B. N. Serrano, L. Shin, H. Lupien, M. Gao, N. Verzi, M. P. Chromatin Profiling Reveals Regulatory Network Shifts and a Protective Role for HNF4A during Colitis. Mol Cell Biol, 34:3291-3304, . (PMID: 24980432, PMCID: PMC4135557)

Yu, S. Nie, Y. Knowles, B. Sakamori, R. Stypulkowski, E. Patel, C. Das, S. Douard, V. Ferraris, R. P. Bonder, E. M. Goldenring, J. R. Tony Ip, Y. Gao, N. TLR sorting by Rab11 endosomes maintains intestinal epithelial-microbial homeostasis. EMBO J, 33:1882-1895, . (PMID: 25063677, PMCID: PMC4195784)

DeGraff, D. J. Grabowska, M. M. Case, T. C. Yu, X. Herrick, M. K. Hayward, W. J. Strand, D. W. Cates, J. M. Hayward, S. W. Gao, N. Walter, M. A. Buttyan, R. Yi, Y. Kaestner, K. H. Matusik, R. J. FOXA1 deletion in luminal epithelium causes prostatic hyperplasia and alteration of differentiated phenotype. Lab Invest, 94:726-739, . (PMID: 24840332)

Perekatt, A. O. Valdez, M. J. Davila, M. Hoffman, A. Bonder, E. M. Gao, N. Verzi, M. P. YY1 is indispensable for Lgr5+ intestinal stem cell renewal. Proc Natl Acad Sci U S A, 111:7695-7700, . (PMID: 24821761, PMCID: PMC4040551)

Ren, J. Yu, S. Gao, N. Zou, Q. Indentation quantification for in-liquid nanomechanical measurement of soft material using an atomic force microscope: Rate-dependent elastic modulus of live cells. Phys Rev E Stat Nonlin Soft Matter Phys, 88:052711, . (PMID: 24329300, PMCID: PMC4172360)

Das, S. Yu, S. Sakamori, R. Stypulkowski, E. Gao, N. Wntless in Wnt secretion: molecular, cellular and genetic aspects. Front Biol (Beijing), 7:587-593, . (PMID: 23439944, PMCID: PMC3578231)

Sakamori, R. Das, S. Yu, S. Feng, S. Stypulkowski, E. Guan, Y. Douard, V. Tang, W. Ferraris, R. P. Harada, A. Brakebusch, C. Guo, W. Gao, N. Cdc42 and Rab8a are critical for intestinal stem cell division, survival, and differentiation in mice. J Clin Invest, 122:1052-1065, . (PMID: 22354172, PMCID: PMC3287229)

Gao, N. Davuluri, G. Gong, W. Seiler, C. Lorent, K. Furth, E. E. Kaestner, K. H. Pack, M. The nuclear pore complex protein Elys is required for genome stability in mouse intestinal epithelial progenitor cells. Gastroenterology, 140:1547-55.e10, . (PMID: 21315719, PMCID: PMC3282118)