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Dipak K. Sarkar, PhD

Publications since 2011

Zhang, C. Franklin, T. Sarkar, D. K. Inhibition of Mammary Cancer Progression in Fetal Alcohol Exposed Rats by beta-Endorphin Neurons. Alcohol Clin Exp Res, 40:134-140, . (PMID: 26727531, PMCID: PMC4700554)

Crews FT Ph, D. Sarkar DK Ph D, D. Phil Qin L Ph, D. Zou J Ph, D. Boyadjieva N M D Ph D, D. Sci Vetreno RP Ph, D. Neuroimmune Function and the Consequences of Alcohol Exposure. Alcohol Res, 37:331-351, . (PMID: 26695754, PMCID: PMC4590627)

Kim, Y. K. Zuccaro, M. V. Zhang, C. Sarkar, D. Quadro, L. Alcohol exposure in utero perturbs retinoid homeostasis in adult rats. Hepatobiliary Surg Nutr, 4:268-277, . (PMID: 26312243, PMCID: PMC4526764)

Sarkar, D. K. Male germline transmits fetal alcohol epigenetic marks for multiple generations: a review. Addict Biol, In process, . (PMID: 25581210)

Sarkar, D. K. Fetal alcohol exposure increases susceptibility to carcinogenesis and promotes tumor progression in prostate gland. Adv Exp Med Biol, 815:389-402, . (PMID: 25427920)

Logan, R. W. Wynne, O. Maglakelidze, G. Zhang, C. O'Connell, S. Boyadjieva, N. I. Sarkar, D. K. beta-Endorphin Neuronal Transplantation Into the Hypothalamus Alters Anxiety-Like Behaviors in Prenatal Alcohol-Exposed Rats and Alcohol-Non-Preferring and Alcohol-Preferring Rats. Alcohol Clin Exp Res, 39:146-157, . (PMID: 25623413)

Gangisetty, O. Wynne, O. Jabbar, S. Nasello, C. Sarkar, D. K. Fetal Alcohol Exposure Reduces Dopamine Receptor D2 and Increases Pituitary Weight and Prolactin Production via Epigenetic Mechanisms. PLoS One, 10:e0140699, . (PMID: 26509893, PMCID: PMC4624904)

Murugan, S. Boyadjieva, N. Sarkar, D. K. Protective effects of hypothalamic Beta-endorphin neurons against alcohol-induced liver injuries and liver cancers in rat animal models. Alcohol Clin Exp Res, 38:2988-2997, . (PMID: 25581653, PMCID: PMC4293083)

Zhang, C. Murugan, S. Boyadjieva, N. I. Jabbar, S. Shrivastava, P. Sarkar, D. K. Beta-endorphin Cell Therapy for Cancer Prevention. Cancer Prev Res (Phila), In process, . (PMID: 25403848)

Bekdash, R. Zhang, C. Sarkar, D. Fetal Alcohol Programming of Hypothalamic Proopiomelanocortin System by Epigenetic Mechanisms and Later Life Vulnerability to Stress. Alcohol Clin Exp Res, In process, . (PMID: 25069392)

Agapito, M. A. Zhang, C. Murugan, S. Sarkar, D. K. Fetal alcohol exposure disrupts metabolic signaling in hypothalamic proopiomelanocortin neurons via a circadian mechanism in male mice. Endocrinology, 155:2578-2588, . (PMID: 24797626, PMCID: PMC4060182)

Rachdaoui, N. Sarkar, D. K. Transgenerational epigenetics and brain disorders. Int Rev Neurobiol, 115:51-73, . (PMID: 25131542)

Chastain, L. G. Sarkar, D. K. Role of microglia in regulation of ethanol neurotoxic action. Int Rev Neurobiol, 118:81-103, . (PMID: 25175862)

Gangisetty, O. Bekdash, R. Maglakelidze, G. Sarkar, D. K. Fetal Alcohol Exposure Alters Proopiomelanocortin Gene Expression and Hypothalamic-Pituitary-Adrenal Axis Function via Increasing MeCP2 Expression in the Hypothalamus. PLoS One, 9:e113228, . (PMID: 25409090, PMCID: PMC4237387)

Rachdaoui, N. Sarkar, D. K. Effects of alcohol on the endocrine system. Endocrinol Metab Clin North Am, 42:593-615, . (PMID: 24011889, PMCID: PMC3767933)

Boyadjieva, N. I. Sarkar, D. K. Cyclic adenosine monophosphate and brain-derived neurotrophic factor decreased oxidative stress and apoptosis in developing hypothalamic neuronal cells: role of microglia. Alcohol Clin Exp Res, 37:1370-1379, . (PMID: 23550806, PMCID: PMC3706564)

Cermakian, N. Lange, T. Golombek, D. Sarkar, D. Nakao, A. Shibata, S. Mazzoccoli, G. Crosstalk between the circadian clock circuitry and the immune system. Chronobiol Int, 30:870-888, . (PMID: 23697902)

Murugan, S. Zhang, C. Mojtahedzadeh, S. Sarkar, D. K. Alcohol Exposure in Utero Increases Susceptibility to Prostate Tumorigenesis in Rat Offspring. Alcohol Clin Exp Res, In process, . (PMID: 23889735)

Bekdash, R. A. Zhang, C. Sarkar, D. K. Gestational choline supplementation normalized fetal alcohol-induced alterations in histone modifications, DNA methylation, and proopiomelanocortin (POMC) gene expression in beta-endorphin-producing POMC neurons of the hypothalamus. Alcohol Clin Exp Res, 37:1133-1142, . (PMID: 23413810, PMCID: PMC3659188)

Logan, R. W. Wynne, O. Levitt, D. Price, D. Sarkar, D. K. Altered circadian expression of cytokines and cytolytic factors in splenic natural killer cells of Per1(-/-) mutant mice. J Interferon Cytokine Res, 33:108-114, . (PMID: 23402528, PMCID: PMC3595954)

Logan, R. W. Sarkar, D. K. Genetic variation of the natural killer gene complex has a role in lung cancer susceptibility. J Thorac Dis, 5:3-5, . (PMID: 23372942, PMCID: PMC3548001)

Sarkar, D. K. Zhang, C. Beta-endorphin neuron regulates stress response and innate immunity to prevent breast cancer growth and progression. Vitam Horm, 93:263-276, . (PMID: 23810011)

Zhang, C. Sarkar, D. K. beta-endorphin neuron transplantation: A possible novel therapy for cancer prevention. Oncoimmunology, 1:552-554, . (PMID: 22754784, PMCID: PMC3382900)

Sengupta, A. Sarkar, D. K. Estrogen inhibits D2S receptor-regulated Gi3 and Gs protein interactions to stimulate prolactin production and cell proliferation in lactotropic cells. J Endocrinol, 214:67-78, . (PMID: 22573829)

Sarkar, D. K. Sengupta, A. Zhang, C. Boyadjieva, N. Murugan, S. Opiate antagonist prevents mu- and delta-opiate receptor dimerization to facilitate ability of agonist to control ethanol-altered natural killer cell functions and mammary tumor growth. J Biol Chem, 287:16734-16747, . (PMID: 22451667, PMCID: PMC3351352)

Logan, R. W. Zhang, C. Murugan, S. O'Connell, S. Levitt, D. Rosenwasser, A. M. Sarkar, D. K. Chronic shift-lag alters the circadian clock of NK cells and promotes lung cancer growth in rats. J Immunol, 188:2583-2591, . (PMID: 22308312, PMCID: PMC3294088)

Sarkar, D. K. Murugan, S. Zhang, C. Boyadjieva, N. Regulation of cancer progression by beta-endorphin neuron. Cancer Res, 72:836-840, . (PMID: 22287549, PMCID: PMC3288320)

Logan, R. W. Sarkar, D. K. Circadian nature of immune function. Mol Cell Endocrinol, 349:82-90, . (PMID: 21784128)

Sengupta, A. Sarkar, D. K. Roles of dopamine 2 receptor isoforms and g proteins in ethanol regulated prolactin synthesis and lactotropic cell proliferation. PLoS One, 7:e45593, . (PMID: 23029123, PMCID: PMC3445509)

Sarkar, D. K. Zhang, C. Murugan, S. Dokur, M. Boyadjieva, N. I. Ortiguela, M. Reuhl, K. R. Mojtehedzadeh, S. Transplantation of beta-endorphin neurons into the hypothalamus promotes immune function and restricts the growth and metastasis of mammary carcinoma. Cancer Res, 71:6282-6291, . (PMID: 21835894, PMCID: PMC3185148)

Logan, R. W. Arjona, A. Sarkar, D. K. Role of sympathetic nervous system in the entrainment of circadian natural-killer cell function. Brain Behav Immun, 25:101-109, . (PMID: 20816749, PMCID: PMC2991610)

Radl, D. B. Ferraris, J. Boti, V. Seilicovich, A. Sarkar, D. K. Pisera, D. Dopamine-induced apoptosis of lactotropes is mediated by the short isoform of d2 receptor. PLoS One, 6:e18097, . (PMID: 21464994, PMCID: PMC3064585)