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Spencer A. Knapp, PhD

Selected Publications

  1. Eun J. Kim, Benjamin Amorelli, Mohannad Abdo, Craig J. Thomas, Dona C. Love, Spencer Knapp, and John A. Hanover. “Distinctive Inhibition of OGA Isoforms by an alpha-GlcNAc Thiolsulfonate” J. Am. Chem. Soc. 2007, 129, 14854.
  2. Alexander Gosslau, Srihari Pabbaraja, Spencer Knapp, and Kuang Yu Chen. “Trans- and Cis-Stilbene Polyphenols Induced Rapid Perinuclear Mitochondrial Clustering and p53-Independent Aptosis in Cancer Cells But Not Normal Cells” Eur. J. Pharmacol. 2008, 587, 25.
  3. Benjamin Amorelli, Chunhua Yang, Brian Rempel, Stephen G. Withers, and Spencer Knapp. “N-Acetylhexosaminidase Inhibitory Properties of C-1 Homologated GlcNAc- and GalNAc-Thiazolines” Bioorg. Med. Chem. Lett. 2008, 18, 2944.
  4. Mohannad Abdo and Spencer Knapp. “Biomimetic Seleninates and Selenonates” J. Am. Chem. Soc. 2008, 130, 9234.
  5. Chad Slawson, T. Lakshmanan, Spencer Knapp, and Gerald W. Hart. “A Mitotic GlcNAcylation/Phosphorylation Signaling Complex Alters the Post-Translational State of the Cytoskeletal Protein Vimentin” Mol. Biol. Cell 2008, 19, 4130.
  6. Mohannad Abdo, Sijiu Liu, Bo Zhou, Chad D. Walls, Spencer Knapp, and Zhong-Yin Zhang. “Seleninate in Place of Phosphate: Irreversible Inhibition of Protein Tyrosine Phosphatases” J. Am. Chem. Soc. 2008, 130, 13196.
  7. Spencer Knapp, David Fash,^ Mohannad Abdo, Thomas J. Emge, and Paul R. Rablen. “GlcNAc-Thiazoline Conformations” Bioorg. Med. Chem. 2009, 17, 1831.
  8. James M. Macdonald, Chris A. Tarling, Edward J. Taylor, Rebecca J. Dennis, David S. Myers, Spencer Knapp, Gideon J. Davies, and Stephen G. Withers. "Chitinase Inhibition by Chitobiose and Chitotriose Thiazolines" Angewandte Chem. Internat. Ed. Engl.  2010, 49, 2599.
  9. Kehinde Ajayi, Vinay V. Thakur, Robert C. Lapo, and Spencer Knapp. “Intramolecular alpha-Glucosaminidation: Synthesis of Mycothiol” Org. Lett. 2010, 12, 2630.
  10. Mohannad Abdo, Zong Zhang, Vern L. Schramm, and Spencer Knapp.  “Electrophilic Aromatic Selenylation:  New OPRT Inhibitors” Org. Lett. 2010, 12, 2982.
  11. Eun Ju Kim, Dona C. Love, Etzer Darout, Mohannad Abdo, Brian Rempel, Stephen G. Withers, Paul R. Rablen, John A. Hanover, and Spencer Knapp. “OGA Inhibition by GlcNAc-selenazoline” Bioorg. Med. Chem. 2010, 18, 7058.
  12. Mohannad Abdo and Spencer Knapp. “Mechanism of a Redox Coupling of Seleninic Acid with Thiol”  J. Org. Chem., 2012, 77, 3433.
  13. Walter S. Won and Spencer Knapp. “b-D-Arabinosyl 1-C-Sulfonic Acid” J. Sulfur Chem. 2013, 34, 33. DOI:10.1080/17415993.2012.7068
  14. Mohannad Abdo, Zhexun Sun and Spencer Knapp. “Biohybrid -Se-S- Coupling Reactions of an Amino Acid Derived Seleninate” Molecules 2013, 18, 1963; DOI:10.3390/molecules18021963
  15. Jian Liu, Zheng Wang, Aaron Levin, Thomas J. Emge, Paul R. Rablen, David M. Floyd, and Spencer Knapp. “N-Methylimidazole Promotes the Reaction of Homophthalic Anhydride with Imines” J. Org. Chem. 2014, 79, 7593.