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Zhaohui Feng, MD, PhD

Publications since 2011

Zhang, C. Liu, J. Tan, C. Yue, X. Zhao, Y. Peng, J. Wang, X. Laddha, S. V. Chan, C. S. Zheng, S. Hu, W. Feng, Z. microRNA-1827 represses MDM2 to positively regulate tumor suppressor p53 and suppress tumorigenesis. Oncotarget, In process, . (PMID: 26840028)

Zhang, C. Liu, J. Zhao, Y. Yue, X. Zhu, Y. Wang, X. Wu, H. Blanco, F. Li, S. Bhanot, G. Haffty, B. G. Hu, W. Feng, Z. Glutaminase 2 is a novel negative regulator of small GTPase Rac1 and mediates p53 function in suppressing metastasis. Elife, In process, . (PMID: 26751560)

Yue, X. Zhao, Y. Liu, J. Zhang, C. Yu, H. Wang, J. Zheng, T. Liu, L. Li, J. Feng, Z. Hu, W. BAG2 promotes tumorigenesis through enhancing mutant p53 protein levels and function. Elife, In process, . (PMID: 26271008)

Zhao, Y. Zhang, C. Yue, X. Li, X. Liu, J. Yu, H. Belyi, V. A. Yang, Q. Feng, Z. Hu, W. Pontin, a new mutant p53-binding protein, promotes gain-of-function of mutant p53. Cell Death Differ, In process, . (PMID: 25857266)

Liu, J. Zhang, C. Wu, R. Lin, M. Liang, Y. Liu, J. Wang, X. Yang, B. Feng, Z. RRAD inhibits the Warburg effect through negative regulation of the NF-kappaB signaling. Oncotarget, In process, . (PMID: 25893381)

Liu, J. Zhang, C. Hu, W. Feng, Z. Tumor suppressor p53 and its mutants in cancer metabolism. Cancer Lett, 356:197-203, . (PMID: 24374014, PMCID: PMC4069248)

Zhang, C. Liu, J. Wang, X. Feng, Z. The regulation of the p53/MDM2 feedback loop by microRNAs. RNA Dis, 2:e502, . (PMID: 25995995, PMCID: PMC4435570)

Wu, H. Schiff, D. S. Lin, Y. Neboori, H. J. Goyal, S. Feng, Z. Haffty, B. G. Ionizing Radiation Sensitizes Breast Cancer Cells to Bcl-2 Inhibitor, ABT-737, through Regulating Mcl-1. Radiat Res, In process, . (PMID: 25409124)

Liu, J. Zhang, C. Wang, X. L. Ly, P. Belyi, V. Xu-Monette, Z. Y. Young, K. H. Hu, W. Feng, Z. E3 ubiquitin ligase TRIM32 negatively regulates tumor suppressor p53 to promote tumorigenesis. Cell Death Differ, 21:1792-1804, . (PMID: 25146927, PMCID: PMC4211364)

Zhang, C. Liu, J. Wang, X. Wu, R. Lin, M. Laddha, S. V. Yang, Q. Chan, C. S. Feng, Z. MicroRNA-339-5p inhibits colorectal tumorigenesis through regulation of the MDM2/p53 signaling. Oncotarget, 5:9106-9117, . (PMID: 25193859)

Zhang, C. Liu, J. Wu, R. Liang, Y. Lin, M. Liu, J. Chan, C. S. Hu, W. Feng, Z. Tumor suppressor p53 negatively regulates glycolysis stimulated by hypoxia through its target RRAD. Oncotarget, 5:5535-5546, . (PMID: 25114038, PMCID: PMC4170611)

Liu, J. Zhang, C. Lin, M. Zhu, W. Liang, Y. Hong, X. Zhao, Y. Young, K. H. Hu, W. Feng, Z. Glutaminase 2 negatively regulates the PI3K/AKT signaling and shows tumor suppression activity in human hepatocellular carcinoma. Oncotarget, 5:2635-2647, . (PMID: 24797434, PMCID: PMC4058033)

Liu, J. Zhang, C. Feng, Z. Tumor suppressor p53 and its gain-of-function mutants in cancer. Acta Biochim Biophys Sin (Shanghai), 46:170-179, . (PMID: 24374774, PMCID: PMC3932832)

Li, X. Yang, Q. Yu, H. Wu, L. Zhao, Y. Zhang, C. Yue, X. Liu, Z. Wu, H. Haffty, B. G. Feng, Z. Hu, W. LIF promotes tumorigenesis and metastasis of breast cancer through the AKT-mTOR pathway. Oncotarget, 5:788-801, . (PMID: 24553191, PMCID: PMC3996668)

Yu, H. Yue, X. Zhao, Y. Li, X. Wu, L. Zhang, C. Liu, Z. Lin, K. Xu-Monette, Z. Y. Young, K. H. Liu, J. Shen, Z. Feng, Z. Hu, W. LIF negatively regulates tumour-suppressor p53 through Stat3/ID1/MDM2 in colorectal cancers. Nat Commun, 5:5218, . (PMID: 25323535, PMCID: PMC4203416)

Giacobbe, A. Bongiorno-Borbone, L. Bernassola, F. Terrinoni, A. Markert, E. K. Levine, A. J. Feng, Z. Agostini, M. Zolla, L. Agro, A. F. Notterman, D. A. Melino, G. Peschiaroli, A. p63 regulates glutaminase 2 expression. Cell Cycle, 12:1395-1405, . (PMID: 23574722, PMCID: PMC3674067)

Liang, Y. Liu, J. Feng, Z. The regulation of cellular metabolism by tumor suppressor p53. Cell Biosci, 3:9, . (PMID: 23388203, PMCID: PMC3573943)

Zheng, T. Wang, J. Zhao, Y. Zhang, C. Lin, M. Wang, X. Yu, H. Liu, L. Feng, Z. Hu, W. Spliced MDM2 isoforms promote mutant p53 accumulation and gain-of-function in tumorigenesis. Nat Commun, 4:2996, . (PMID: 24356649, PMCID: PMC3960723)

Zhang, C. Liu, J. Liang, Y. Wu, R. Zhao, Y. Hong, X. Lin, M. Yu, H. Liu, L. Levine, A. J. Hu, W. Feng, Z. Tumour-associated mutant p53 drives the Warburg effect. Nat Commun, 4:2935, . (PMID: 24343302, PMCID: PMC3969270)

Liu, J. Feng, Z. PTEN, energy metabolism and tumor suppression. Acta Biochim Biophys Sin (Shanghai), 44:629-631, . (PMID: 22751612)

Feng, Z. Liu, L. Zhang, C. Zheng, T. Wang, J. Lin, M. Zhao, Y. Wang, X. Levine, A. J. Hu, W. Chronic restraint stress attenuates p53 function and promotes tumorigenesis. Proc Natl Acad Sci U S A, 109:7013-7018, . (PMID: 22509031, PMCID: PMC3345015)

Hu, W. Feng, Z. Levine, A. J. The Regulation of Multiple p53 Stress Responses is Mediated through MDM2. Genes Cancer, 3:199-208, . (PMID: 23150753, PMCID: PMC3494373)

Liu, J. Lin, M. Zhang, C. Wang, D. Feng, Z. Hu, W. TAp63gamma enhances nucleotide excision repair through transcriptional regulation of DNA repair genes. DNA Repair (Amst), 11:167-176, . (PMID: 22056305, PMCID: PMC3348579)

Zhang, C. Lin, M. Wu, R. Wang, X. Yang, B. Levine, A. J. Hu, W. Feng, Z. Parkin, a p53 target gene, mediates the role of p53 in glucose metabolism and the Warburg effect. Proc Natl Acad Sci U S A, 108:16259-16264, . (PMID: 21930938, PMCID: PMC3182683)

Tang, M. S. Wang, H. T. Hu, Y. Chen, W. S. Akao, M. Feng, Z. Hu, W. Acrolein induced DNA damage, mutagenicity and effect on DNA repair. Mol Nutr Food Res, 55:1291-1300, . (PMID: 21714128)

Feng, Z. Zhang, C. Kang, H. J. Sun, Y. Wang, H. Naqvi, A. Frank, A. K. Rosenwaks, Z. Murphy, M. E. Levine, A. J. Hu, W. Regulation of female reproduction by p53 and its family members. FASEB J, 25:2245-2255, . (PMID: 21402718, PMCID: PMC3114525)

Feng, Z. Lin, M. Wu, R. The Regulation of Aging and Longevity: A New and Complex Role of p53. Genes Cancer, 2:443-452, . (PMID: 21779512, PMCID: PMC3135645)

Feng, Z. Zhang, C. Wu, R. Hu, W. Tumor suppressor p53 meets microRNAs. J Mol Cell Biol, 3:44-50, . (PMID: 21278451, PMCID: PMC3030969)