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Changshun Shao, PhD

Selected Publications

  1. Liang L, Mendonca MS, Deng L, Nguyen SC, Shao C, Tischfield JA. 2007. Reduced apoptosis and increased deletion mutations in vivo in mice exposed to repeated ionizing radiation. Cancer Research 67:1920-1917.
  2. Liang L, Deng L, Mendonca MS, Chen Y, Stambrook PJ, Shao C, Tischfield JA. 2007. X-rays induce distinct patterns of somatic mutation in fetal versus adult hematopoietic cells. DNA Repair 6:1380-1385.
  3. Liang L, Deng L, Nguyen SC, Zhao X, Maulion C, Shao C, Tischfield JA. 2008. Human DNA ligases I and III, but not ligase IV, are required for microhomology-mediated end joining of DNA double-strand breaks. Nucleic Acids Research 36:3297-3310.
  4. Barrera-Oro J, Liu TY, Gorden E, Kucherlapati R, Shao C, Tischfield JA. 2008. Role of the mismatch repair gene, Msh6, in suppressing genome instability and radiation-induced mutations. Mutation Research 642:74-79.
  5. Liu Z, Liu Q, Xu B, Wu J, Guo C, Zhu F, Yang Q, Gao G, Gong Y, Shao C. 2009. Berberine induces p53-dependent cell cycle arrest and apoptosis of human osteosarcoma cells by inflicting DNA damage. Mutation Research 662:75-83.
  6. Tereshchenko IV, Chen Y, McDaniel LD, Schultz RA, Tischfield JA, Shao C. 2010. Small scale genetic alterations contribute to increased mutability at the X-linked Hprt locus in vivo in Blm hypomorphic mice. DNA Repair 9:551-557.
  7. Zhao X, Ren G, Liang L, Ai P, Zheng B, Tischfield JA, Shi Y, Shao C. 2010. IFNgamma induces expansion of Lin-Sca-1+c-Kit+ cells. Stem Cells 28:122-126.
  8. Denissova NG, Tereschenko IV, Cui E, Stambrook PJ, Shao C, Tischfield JA. 2011. Ionizing radiation is a potent inducer of mitotic recombination in mouse embryonic stem cells. Mutation Research 715:1-6.
  9. Xu B, Sun Z, Liu Z, Guo H, Liu Q, Jiang H, Zou Y, Gong Y, Tischfield JA, Shao C. 2011. Replication stress induces micronuclei comprising aggregated DNA double-strand breaks. PLoS ONE 6(4):e18618.
  10. Wu J, Liu Z, Shao C, Gong Y, Hernando E, Lee P, Narita M, Muller W, Liu J, Wei JJ. 2011. HMGA2 overexpression-induced ovarian surface epithelial transformation is mediated through regulation of EMT genes. Cancer Research 71:349-359.
  11. Rani V, Neumann CA, Shao C, Tischfield JA. 2012. Prdx1 deficiency promotes tissue specific loss of heterozygosity mediated by deficiency in DNA repair and increased oxidative stress. Mutation Research 735:39-45.
  12. Ren G, Zhao X, Wang Y, Zhang X, Chen X, Xu C, Yuan ZR, Roberts AI, Zhang L, Zheng B, Wen T, Han Y, Rabson AB, Tischfield JA, Shao C, Shi Y. 2012. CCR2-dependent recruitment of monocytes/macrophages by tumor educated mesenchymal stromal cells promotes tumor development and is mimicked by TNF-alpha. Cell Stem Cell 11:812-824.
  13. Guo H, Liu Z, Xu B, Hu H, Wei Z, Liu Q, Zhang X, Ding X, Wang Y, Zhao M, Gong Y, Shao C. 2013. Chemokine receptor CXCR2 is transactivated by p53 and induces p38-mediated cellular senescence in response to DNA damage. Aging Cell 12:1110-1121.
  14. Ren G, Liu Y, Zhao X, Zheng B, Yuan ZR, Zhang L, Tischfield JA, Shao C, Shi Y. 2014. Tumor stromal cells endow naïve stromal cells with tumor-promoting properties. Oncogene (Epub ahead of print).