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Celeste M. Nelson, PhD

Publications since 2011

Nelson, C. M. Collective migration in tissues. Mol Biol Cell, 27:877, . (PMID: 26976930)

Piotrowski-Daspit, A. S. Tien, J. Nelson, C. M. Interstitial fluid pressure regulates collective invasion in engineered human breast tumors via Snail, vimentin, and E-cadherin. Integr Biol (Camb), In process, . (PMID: 26853861)

Navis, A. Nelson, C. M. Pulling together: Tissue-generated forces that drive lumen morphogenesis. Semin Cell Dev Biol, In process, . (PMID: 26778757)

Kim, H. Y. Pang, M. F. Varner, V. D. Kojima, L. Miller, E. Radisky, D. C. Nelson, C. M. Localized Smooth Muscle Differentiation Is Essential for Epithelial Bifurcation during Branching Morphogenesis of the Mammalian Lung. Dev Cell, 34:719-726, . (PMID: 26387457)

Siedlik, M. J. Varner, V. D. Nelson, C. M. Pushing, pulling, and squeezing our way to understanding mechanotransduction. Methods, In process, . (PMID: 26318086)

Varner, V. D. Gleghorn, J. P. Miller, E. Radisky, D. C. Nelson, C. M. Mechanically patterning the embryonic airway epithelium. Proc Natl Acad Sci U S A, In process, . (PMID: 26170292)

Pang, M. F. Georgoudaki, A. M. Lambut, L. Johansson, J. Tabor, V. Hagikura, K. Jin, Y. Jansson, M. Alexander, J. S. Nelson, C. M. Jakobsson, L. Betsholtz, C. Sund, M. Karlsson, M. C. Fuxe, J. TGF-beta1-induced EMT promotes targeted migration of breast cancer cells through the lymphatic system by the activation of CCR7/CCL21-mediated chemotaxis. Oncogene, In process, . (PMID: 25961925)

Siedlik, M. J. Nelson, C. M. Regulation of tissue morphodynamics: an important role for actomyosin contractility. Curr Opin Genet Dev, In process, . (PMID: 25748251)

Piotrowski, A. S. Varner, V. D. Gjorevski, N. Nelson, C. M. Three-dimensional traction force microscopy of engineered epithelial tissues. Methods Mol Biol, 1189:191-206, . (PMID: 25245695)

Cichon, M. A. Nelson, C. M. Radisky, D. C. Regulation of epithelial-mesenchymal transition in breast cancer cells by cell contact and adhesion. Cancer Inform, 14:1-13, . (PMID: 25698877, PMCID: PMC4325704)

Paluch, E. K. Nelson, C. M. Biais, N. Fabry, B. Moeller, J. Pruitt, B. L. Wollnik, C. Kudryasheva, G. Rehfeldt, F. Federle, W. Mechanotransduction: use the force(s). BMC Biol, 13:47, . (PMID: 26141078)

Gjorevski, N. S Piotrowski, A. Varner, V. D. Nelson, C. M. Dynamic tensile forces drive collective cell migration through three-dimensional extracellular matrices. Sci Rep, 5:11458, . (PMID: 26165921, PMCID: PMC4499882)

Boghaert, E. Radisky, D. C. Nelson, C. M. Lattice-based model of ductal carcinoma in situ suggests rules for breast cancer progression to an invasive state. PLoS Comput Biol, 10:e1003997, . (PMID: 25473842)

Varner, V. D. Nelson, C. M. Cellular and physical mechanisms of branching morphogenesis. Development, 141:2750-2759, . (PMID: 25005470, PMCID: PMC4197615)

Varner, V. D. Nelson, C. M. Toward the Directed Self-Assembly of Engineered Tissues. Annu Rev Chem Biomol Eng, In process, . (PMID: 24797818)

Lee, K. Nelson, C. M. Determining the Role of Matrix Compliance in the Differentiation of Mammary Stem Cells. Methods Mol Biol, 1202:79-94, . (PMID: 24014310)

Gleghorn, J. P. Manivannan, S. Nelson, C. M. Quantitative approaches to uncover physical mechanisms of tissue morphogenesis. Curr Opin Biotechnol, 24:954-961, . (PMID: 23647971, PMCID: PMC3762917)

Nelson, C. M. Forces in Epithelial Origami. Dev Cell, 26:554-556, . (PMID: 24091007)

Tien, J. Nelson, C. M. Microstructured Extracellular Matrices in Tissue Engineering and Development: An Update. Ann Biomed Eng, In process, . (PMID: 24030067)

Varner, V. D. Nelson, C. M. Let's push things forward: disruptive technologies and the mechanics of tissue assembly. Integr Biol (Camb), 5:1162-1173, . (PMID: 23907401)

Kim, H. Y. Varner, V. D. Nelson, C. M. Apical constriction initiates new bud formation during monopodial branching of the embryonic chicken lung. Development, 140:3146-3155, . (PMID: 23824575)

Zhu, W. Nelson, C. M. PI3K regulates branch initiation and extension of cultured mammary epithelia via Akt and Rac1 respectively. Dev Biol, 379:235-245, . (PMID: 23665174, PMCID: PMC3760257)

Chen, Q. K. Lee, K. Radisky, D. C. Nelson, C. M. Extracellular matrix proteins regulate epithelial-mesenchymal transition in mammary epithelial cells. Differentiation, In process, . (PMID: 23660532, PMCID: PMC3762919)

Zhu, W. Nelson, C. M. Adipose and mammary epithelial tissue engineering. Biomatter, In process, . (PMID: 23628872, PMCID: PMC3749276)

Radisky, D. C. Nelson, C. M. Regulation of mechanical stress by mammary epithelial tissue structure controls breast cancer cell invasion. Oncotarget, 4:498-499, . (PMID: 23625757, PMCID: PMC3720598)

Mori, H. Lo, A. T. Inman, J. L. Alcaraz, J. Ghajar, C. M. Mott, J. D. Nelson, C. M. Chen, C. S. Zhang, H. Bascom, J. L. Seiki, M. Bissell, M. J. Transmembrane/cytoplasmic, rather than catalytic, domains of Mmp14 signal to MAPK activation and mammary branching morphogenesis via binding to integrin beta1. Development, 140:343-352, . (PMID: 23250208, PMCID: PMC3597211)

Boghaert, E. Gleghorn, J. P. Lee, K. Gjorevski, N. Radisky, D. C. Nelson, C. M. Host epithelial geometry regulates breast cancer cell invasiveness. Proc Natl Acad Sci U S A, 109:19632-19637, . (PMID: 23150585, PMCID: PMC3511712)

Lui, C. Lee, K. Nelson, C. M. Matrix compliance and RhoA direct the differentiation of mammary progenitor cells. Biomech Model Mechanobiol, 11:1241-1249, . (PMID: 22161021, PMCID: PMC3339284)

Manivannan, S. Nelson, C. M. Dynamics of branched tissue assembly. Stem Cell Res Ther, In process, . (PMID: 23114096, PMCID: PMC3580433)

Lee, K. Chen, Q. K. Lui, C. Cichon, M. A. Radisky, D. C. Nelson, C. M. Matrix compliance regulates Rac1b localization, NADPH oxidase assembly, and epithelial-mesenchymal transition. Mol Biol Cell, 23:4097-4108, . (PMID: 22918955, PMCID: PMC3469523)

Zhu, W. Nelson, C. M. PI3K signaling in the regulation of branching morphogenesis. Biosystems, 109:403-411, . (PMID: 22525052)

Gjorevski, N. Nelson, C. M. Mapping of Mechanical Strains and Stresses around Quiescent Engineered Three-Dimensional Epithelial Tissues. Biophys J, 103:152-162, . (PMID: 22828342, PMCID: PMC3388222)

Chung, J. W. Lee, K. Neikirk, C. Nelson, C. M. Priestley, R. D. Photoresponsive coumarin-stabilized polymeric nanoparticles as a detectable drug carrier. Small, 8:1693-1700, . (PMID: 22454229)

Kim, H. Y. Nelson, C. M. Extracellular matrix and cytoskeletal dynamics during branching morphogenesis. Organogenesis, 8:56-64, . (PMID: 22609561, PMCID: PMC3429513)

Gleghorn, J. P. Kwak, J. Pavlovich, A. L. Nelson, C. M. Inhibitory morphogens and monopodial branching of the embryonic chicken lung. Dev Dyn, 241:852-862, . (PMID: 22410853, PMCID: PMC3443594)

Gjorevski, N. Boghaert, E. Nelson, C. M. Regulation of Epithelial-Mesenchymal Transition by Transmission of Mechanical Stress through Epithelial Tissues. Cancer Microenviron, 5:29-38, . (PMID: 21748438, PMCID: PMC3343202)

Lee, K. Nelson, C. M. New insights into the regulation of epithelial-mesenchymal transition and tissue fibrosis. Int Rev Cell Mol Biol, 294:171-221, . (PMID: 22364874)

Nelson, C. M. Gleghorn, J. P. Sculpting organs: mechanical regulation of tissue development. Annu Rev Biomed Eng, 14:129-154, . (PMID: 22524386)

Tien, J. Truslow, J. G. Nelson, C. M. Modulation of invasive phenotype by interstitial pressure-driven convection in aggregates of human breast cancer cells. PLoS One, 7:e45191, . (PMID: 23028839, PMCID: PMC3445465)

Manivannan, S. Gleghorn, J. P. Nelson, C. M. Engineered tissues to quantify collective cell migration during morphogenesis. Methods Mol Biol, 886:173-182, . (PMID: 22639261)

Gjorevski, N. Nelson, C. M. Integrated morphodynamic signalling of the mammary gland. Nat Rev Mol Cell Biol, 12:581-593, . (PMID: 21829222)

Pavlovich, A. L. Boghaert, E. Nelson, C. M. Mammary branch initiation and extension are inhibited by separate pathways downstream of TGFbeta in culture. Exp Cell Res, 317:1872-1884, . (PMID: 21459084, PMCID: PMC3123406)

Lee, K. Gjorevski, N. Boghaert, E. Radisky, D. C. Nelson, C. M. Snail1, Snail2, and E47 promote mammary epithelial branching morphogenesis. EMBO J, 30:2662-2674, . (PMID: 21610693, PMCID: PMC3155296)

Gomez, E. W. Nelson, C. M. Lithographically defined two- and three-dimensional tissue microarrays. Methods Mol Biol, 671:107-116, . (PMID: 20967625)