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Celeste M. Nelson, PhD

Publications since 2011

Kim, H. Y. Pang, M. F. Varner, V. D. Kojima, L. Miller, E. Radisky, D. C. Nelson, C. M. Localized Smooth Muscle Differentiation Is Essential for Epithelial Bifurcation during Branching Morphogenesis of the Mammalian Lung. Dev Cell, 34:719-726, . (PMID: 26387457)

Siedlik, M. J. Varner, V. D. Nelson, C. M. Pushing, pulling, and squeezing our way to understanding mechanotransduction. Methods, In process, . (PMID: 26318086)

Varner, V. D. Gleghorn, J. P. Miller, E. Radisky, D. C. Nelson, C. M. Mechanically patterning the embryonic airway epithelium. Proc Natl Acad Sci U S A, In process, . (PMID: 26170292)

Pang, M. F. Georgoudaki, A. M. Lambut, L. Johansson, J. Tabor, V. Hagikura, K. Jin, Y. Jansson, M. Alexander, J. S. Nelson, C. M. Jakobsson, L. Betsholtz, C. Sund, M. Karlsson, M. C. Fuxe, J. TGF-beta1-induced EMT promotes targeted migration of breast cancer cells through the lymphatic system by the activation of CCR7/CCL21-mediated chemotaxis. Oncogene, In process, . (PMID: 25961925)

Siedlik, M. J. Nelson, C. M. Regulation of tissue morphodynamics: an important role for actomyosin contractility. Curr Opin Genet Dev, In process, . (PMID: 25748251)

Piotrowski, A. S. Varner, V. D. Gjorevski, N. Nelson, C. M. Three-dimensional traction force microscopy of engineered epithelial tissues. Methods Mol Biol, 1189:191-206, . (PMID: 25245695)

Cichon, M. A. Nelson, C. M. Radisky, D. C. Regulation of epithelial-mesenchymal transition in breast cancer cells by cell contact and adhesion. Cancer Inform, 14:1-13, . (PMID: 25698877, PMCID: PMC4325704)

Paluch, E. K. Nelson, C. M. Biais, N. Fabry, B. Moeller, J. Pruitt, B. L. Wollnik, C. Kudryasheva, G. Rehfeldt, F. Federle, W. Mechanotransduction: use the force(s). BMC Biol, 13:47, . (PMID: 26141078)

Gjorevski, N. S Piotrowski, A. Varner, V. D. Nelson, C. M. Dynamic tensile forces drive collective cell migration through three-dimensional extracellular matrices. Sci Rep, 5:11458, . (PMID: 26165921, PMCID: PMC4499882)

Boghaert, E. Radisky, D. C. Nelson, C. M. Lattice-based model of ductal carcinoma in situ suggests rules for breast cancer progression to an invasive state. PLoS Comput Biol, 10:e1003997, . (PMID: 25473842)

Varner, V. D. Nelson, C. M. Cellular and physical mechanisms of branching morphogenesis. Development, 141:2750-2759, . (PMID: 25005470, PMCID: PMC4197615)

Varner, V. D. Nelson, C. M. Toward the Directed Self-Assembly of Engineered Tissues. Annu Rev Chem Biomol Eng, In process, . (PMID: 24797818)

Lee, K. Nelson, C. M. Determining the Role of Matrix Compliance in the Differentiation of Mammary Stem Cells. Methods Mol Biol, 1202:79-94, . (PMID: 24014310)

Gleghorn, J. P. Manivannan, S. Nelson, C. M. Quantitative approaches to uncover physical mechanisms of tissue morphogenesis. Curr Opin Biotechnol, 24:954-961, . (PMID: 23647971, PMCID: PMC3762917)

Nelson, C. M. Forces in Epithelial Origami. Dev Cell, 26:554-556, . (PMID: 24091007)

Tien, J. Nelson, C. M. Microstructured Extracellular Matrices in Tissue Engineering and Development: An Update. Ann Biomed Eng, In process, . (PMID: 24030067)

Varner, V. D. Nelson, C. M. Let's push things forward: disruptive technologies and the mechanics of tissue assembly. Integr Biol (Camb), 5:1162-1173, . (PMID: 23907401)

Kim, H. Y. Varner, V. D. Nelson, C. M. Apical constriction initiates new bud formation during monopodial branching of the embryonic chicken lung. Development, 140:3146-3155, . (PMID: 23824575)

Zhu, W. Nelson, C. M. PI3K regulates branch initiation and extension of cultured mammary epithelia via Akt and Rac1 respectively. Dev Biol, 379:235-245, . (PMID: 23665174, PMCID: PMC3760257)

Chen, Q. K. Lee, K. Radisky, D. C. Nelson, C. M. Extracellular matrix proteins regulate epithelial-mesenchymal transition in mammary epithelial cells. Differentiation, In process, . (PMID: 23660532, PMCID: PMC3762919)

Zhu, W. Nelson, C. M. Adipose and mammary epithelial tissue engineering. Biomatter, In process, . (PMID: 23628872, PMCID: PMC3749276)

Radisky, D. C. Nelson, C. M. Regulation of mechanical stress by mammary epithelial tissue structure controls breast cancer cell invasion. Oncotarget, 4:498-499, . (PMID: 23625757, PMCID: PMC3720598)

Mori, H. Lo, A. T. Inman, J. L. Alcaraz, J. Ghajar, C. M. Mott, J. D. Nelson, C. M. Chen, C. S. Zhang, H. Bascom, J. L. Seiki, M. Bissell, M. J. Transmembrane/cytoplasmic, rather than catalytic, domains of Mmp14 signal to MAPK activation and mammary branching morphogenesis via binding to integrin beta1. Development, 140:343-352, . (PMID: 23250208, PMCID: PMC3597211)

Boghaert, E. Gleghorn, J. P. Lee, K. Gjorevski, N. Radisky, D. C. Nelson, C. M. Host epithelial geometry regulates breast cancer cell invasiveness. Proc Natl Acad Sci U S A, 109:19632-19637, . (PMID: 23150585, PMCID: PMC3511712)

Lui, C. Lee, K. Nelson, C. M. Matrix compliance and RhoA direct the differentiation of mammary progenitor cells. Biomech Model Mechanobiol, 11:1241-1249, . (PMID: 22161021, PMCID: PMC3339284)

Manivannan, S. Nelson, C. M. Dynamics of branched tissue assembly. Stem Cell Res Ther, In process, . (PMID: 23114096, PMCID: PMC3580433)

Lee, K. Chen, Q. K. Lui, C. Cichon, M. A. Radisky, D. C. Nelson, C. M. Matrix compliance regulates Rac1b localization, NADPH oxidase assembly, and epithelial-mesenchymal transition. Mol Biol Cell, 23:4097-4108, . (PMID: 22918955, PMCID: PMC3469523)

Zhu, W. Nelson, C. M. PI3K signaling in the regulation of branching morphogenesis. Biosystems, 109:403-411, . (PMID: 22525052)

Gjorevski, N. Nelson, C. M. Mapping of Mechanical Strains and Stresses around Quiescent Engineered Three-Dimensional Epithelial Tissues. Biophys J, 103:152-162, . (PMID: 22828342, PMCID: PMC3388222)

Chung, J. W. Lee, K. Neikirk, C. Nelson, C. M. Priestley, R. D. Photoresponsive coumarin-stabilized polymeric nanoparticles as a detectable drug carrier. Small, 8:1693-1700, . (PMID: 22454229)

Kim, H. Y. Nelson, C. M. Extracellular matrix and cytoskeletal dynamics during branching morphogenesis. Organogenesis, 8:56-64, . (PMID: 22609561, PMCID: PMC3429513)

Gleghorn, J. P. Kwak, J. Pavlovich, A. L. Nelson, C. M. Inhibitory morphogens and monopodial branching of the embryonic chicken lung. Dev Dyn, 241:852-862, . (PMID: 22410853, PMCID: PMC3443594)

Gjorevski, N. Boghaert, E. Nelson, C. M. Regulation of Epithelial-Mesenchymal Transition by Transmission of Mechanical Stress through Epithelial Tissues. Cancer Microenviron, 5:29-38, . (PMID: 21748438, PMCID: PMC3343202)

Lee, K. Nelson, C. M. New insights into the regulation of epithelial-mesenchymal transition and tissue fibrosis. Int Rev Cell Mol Biol, 294:171-221, . (PMID: 22364874)

Nelson, C. M. Gleghorn, J. P. Sculpting organs: mechanical regulation of tissue development. Annu Rev Biomed Eng, 14:129-154, . (PMID: 22524386)

Tien, J. Truslow, J. G. Nelson, C. M. Modulation of invasive phenotype by interstitial pressure-driven convection in aggregates of human breast cancer cells. PLoS One, 7:e45191, . (PMID: 23028839, PMCID: PMC3445465)

Manivannan, S. Gleghorn, J. P. Nelson, C. M. Engineered tissues to quantify collective cell migration during morphogenesis. Methods Mol Biol, 886:173-182, . (PMID: 22639261)

Gjorevski, N. Nelson, C. M. Integrated morphodynamic signalling of the mammary gland. Nat Rev Mol Cell Biol, 12:581-593, . (PMID: 21829222)

Pavlovich, A. L. Boghaert, E. Nelson, C. M. Mammary branch initiation and extension are inhibited by separate pathways downstream of TGFbeta in culture. Exp Cell Res, 317:1872-1884, . (PMID: 21459084, PMCID: PMC3123406)

Lee, K. Gjorevski, N. Boghaert, E. Radisky, D. C. Nelson, C. M. Snail1, Snail2, and E47 promote mammary epithelial branching morphogenesis. EMBO J, 30:2662-2674, . (PMID: 21610693, PMCID: PMC3155296)

Gomez, E. W. Nelson, C. M. Lithographically defined two- and three-dimensional tissue microarrays. Methods Mol Biol, 671:107-116, . (PMID: 20967625)