Researcher Profiles

Return to member profile

Karine A. Cohen-Solal, PhD

Selected Publications

  1. Boregowda RK, Olabisi OO, Abushahba W, Jeong BS, Haenssen KK, Chen W, Chekmareva M, Lasfar A, Foran DJ, Goydos JS, Cohen-Solal KA. RUNX2 is overexpressed in melanoma cells and mediates their migration and invasion. Cancer Lett, In process, 2014.
  2. Lasfar A, Cook JR, Cohen Solal KA, Reuhl K, Kotenko SV, Langer J, Laskin DL. Critical Role of the Endogenous IFN Ligand-Receptors in Type I and Type II IFNs Response. Immunology, In process, 2014.
  3. Wen YY, Li J, Koo J, Shin SS, Lin Y, Jeong BS, Mehnert JM, Chen S, Cohen-Solal K, Goydos JS. Activation of the Glutamate Receptor GRM1 Enhances Angiogenic Signaling to Drive Melanoma Progression. Cancer Res, In process, 2014.
  4. Cohen-Solal, K., Reuhl, K. R., Ryan, K. B., Roberts, K. G. And Chen, S.Development of cutaneous amelanotic melanoma in the absence of a functional tyrosinase. Pigment Cell Research (2001) 14, 466-474.
  5. Cohen-Solal, K., Crespo-Carbone, S.M., Namkoong, J., Mackason, K. R., Roberts, K. G, Reuhl, K. R. And Chen, S. Progressive appearance of pigmentation in amelanotic melanoma lesions. Pigment Cell Research (2002) 15, 282-289.
  6. Pollock, P., Cohen-Solal, K., Sood, R., Namkoong, J., Koganti, A., Zhu, H., Robbins, C., Makalowska, I., Martino, J.M., Shin, S., Marin, Y., Roberts, K. G., Yudt, L.M., Chen, A., Cheng, J., Incao, A., Pinkett, H.W., Graham, C.L., Dunn, K., Galdzicki, M., Crespo-Carbone, S.M., Mackason, K. R., Ryan, K.B., Sinsimer, D., Goydos, J., Reuhl, K. R., Eckhaus, M., Meltzer, P.S., Pavan, W.J., Trent, J.M. And Chen, S. Melanoma mouse model implicates metabotropic glutamate signaling in melanocytic neoplasia. Nature Genetics (2003) 34, 108-112.
  7. Cohen-Solal, K., Sood, R., Marin, Y., Crespo-Carbone, S.M., Sinsimer, D., Martino, J.J., Robbins, C., Makalowska, I., Trent, J.M. And Chen, S. Identification and characterization of mouse rab 32 by mrna and protein expression analysis. Biochimica Biophysica Acta (2003) 1651, 68-75.
  8. Marin, Y., Namkoong, J., Cohen-Solal, K., Shin, S., Martino, J., Oka, M. And Chen, S. Stimulation of oncogenic metabotropic glutamate receptor 1 in melanoma cells activates Erk1/2 via PKCe. Cell Signaling (2006) 18, 1279-1286.
  9. Le, M. N., Chan, J. L.-K., Rosenberg, S., Nabatian, A., Merrigan, K., Cohen-Solal, K. and Goydos J. S. The glutamate release inhibitor Riluzole decreases migration, invasion and proliferation of melanoma cells. Journal of Investigative Dermatology (2010) 130, 2240-2249.
  10. Lasfar, A. and Cohen-Solal, K. Resistance to Transforming Growth Factor-β-mediated tumor suppression in melanoma: Are multiple mechanisms in place? Carcinogenesis (2010) 31, 1710-1717.
  11. Cohen-Solal, K.,  Merrigan, K., Chan, J. L.-K., Goydos J. S., Chen, W., Foran, D.J., Liu, F., Lasfar, A. and Reiss, M. Constitutive Smad linker phosphorylation in melanoma: A mechanism of resistance to Transforming Growth Factor-β-mediated tumor suppression. Pigment Cell Melanoma Res. (2011) 24. 512-524
  12. Lasfar, A, Abushahba, W., Balan, M. and Cohen-Solal, K.  Interferon lambda: A new sword in cancer immunotherapy. (2011) Clinical and Developmental Immunology (2011);2011:349575. Epub 2011 Dec 6.?Abushahba, W., Olabisi, O. O., Jeong, B-S., Boregowda, R. K. , Wen, Y., Liu, F., Goydos, J. S., Lasfar, A. and Cohen-Solal, K. Non-canonical Smads phosphorylation induced by the glutamate release inhibitor, riluzole, through GSK3 activation in melanoma. In Press in PLoS ONE, 2012. DOI 10.1371/journal.pone.0047312 ?Cohen-Solal, K., Bailly, A., Rauch, C., Quesne, M. And Milgrom, E. "Specific binding of progesterone receptor to progesterone-responsive elements does not require prior dimerization". Eur. J. Biochem. (1993) 214, 189-195.
  13. Chauchereau, A., Cohen-Solal, K., Jolivet, A., Bailly, A. And Milgrom, E. "Phosphorylation sites in ligand-induced and ligand-independent activation of the progesterone receptor". Biochemistry (1994) 33, 14333-14338.
  14. Cohen-Solal, K., Villeval, J. L., Titeux, M., Lok, S., Vainchenker, W. And Wendling, F. Constitutive expression of mpl ligand transcripts during thrombocytopenia or thrombocytosis. Blood (1996) 88, 2578-2584.
  15. Cohen-Solal, K., Debili, N., Vainchenker, W. And Wendling, F. Thrombopoietin (Mpl Ligand) and the regulation of platelet production. Thrombosis And Haemostasis (1997) 78, 37-41.
  16. Villeval, J. L., Cohen-Solal, K., Tulliez, M., Giraudier, S., Guichard, J., Burstein, S., Cramer, E., Vainchenker, W. And Wendling, F. High thrombopoietin production by hematopoietic cells induces a fatal myeloproliferative syndrome in mice. Blood (1997) 90, 4369-4383.