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Roger A. Jones, PhD

Publications since 2011

Meehan, R. E. Torgerson, C. D. Gaffney, B. L. Jones, R. A. Strobel, S. A. Nuclease-Resistant c-di-AMP Derivatives That Differentially Recognize RNA and Protein Receptors. Biochemistry, In process, . (PMID: 26789423)

Ren, A. Wang, X. C. Kellenberger, C. A. Rajashankar, K. R. Jones, R. A. Hammond, M. C. Patel, D. J. Structural Basis for Molecular Discrimination by a 3',3'-cGAMP Sensing Riboswitch. Cell Rep, In process, . (PMID: 25818298)

Gaffney, B. L. Jones, R. A. Synthesis of c-di-GMP Analogs with Thiourea, Urea, Carbodiimide, and Guanidinium Linkages. Org Lett, 16:158-161, . (PMID: 24313312, PMCID: PMC3933394)

Veliath, E. Gaffney, B. L. Jones, R. A. Synthesis of Capped RNA using a DMT Group as a Purification Handle. Nucleosides Nucleotides Nucleic Acids, 33:40-52, . (PMID: 24588755)

Gao, P. Ascano, M. Zillinger, T. Wang, W. Dai, P. Serganov, A. A. Gaffney, B. L. Shuman, S. Jones, R. A. Deng, L. Hartmann, G. Barchet, W. Tuschl, T. Patel, D. J. Structure-Function Analysis of STING Activation by c[G(2',5')pA(3',5')p] and Targeting by Antiviral DMXAA. Cell, 154:748-762, . (PMID: 23910378)

Gao, P. Ascano, M. Wu, Y. Barchet, W. Gaffney, B. L. Zillinger, T. Serganov, A. A. Liu, Y. Jones, R. A. Hartmann, G. Tuschl, T. Patel, D. J. Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase. Cell, 153:1094-1107, . (PMID: 23647843)

Gaffney, B. L. Stebbins, N. D. Jones, R. A. Synthesis of biotinylated c-di-gmp and c-di-amp using click conjugation. Nucleosides Nucleotides Nucleic Acids, 32:1-16, . (PMID: 23360291, PMCID: PMC3561633)

Gaffney, B. L. Jones, R. A. One-flask synthesis of cyclic diguanosine monophosphate (c-di-GMP). Curr Protoc Nucleic Acid Chem, Chapter 14:Unit 14.8.1-Unit 14.8.7, . (PMID: 22395965, PMCID: PMC3319711)

Veliath, E. Kim, S. Gaffney, B. L. Jones, R. A. Synthesis and characterization of C8 analogs of c-di-GMP. Nucleosides Nucleotides Nucleic Acids, 30:961-978, . (PMID: 22060558)

Shanahan, C. A. Gaffney, B. L. Jones, R. A. Strobel, S. A. Differential analogue binding by two classes of c-di-GMP riboswitches. J Am Chem Soc, 133:15578-15592, . (PMID: 21838307, PMCID: PMC3183120)