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Kathleen W. Scotto, PhD

Publications since 2011

Tedeschi, P. M. Lin, H. Gounder, M. Kerrigan, J. E. Abali, E. E. Scotto, K. Bertino, J. Suppression of Cytosolic NADPH Pool by Thionicotinamide Increases Oxidative Stress and Synergizes with Chemotherapy. Mol Pharmacol, In process, . (PMID: 26219913)

Munoz, J. L. Walker, N. D. Scotto, K. W. Rameshwar, P. Temozolomide competes for P-glycoprotein and contribute to chemoresistance in glioblastoma cells. Cancer Lett, In process, . (PMID: 26208431)

Shi, J. Pabon, K. Scotto, K. W. Methylxanthines Increase Expression of the Splicing Factor SRSF2 by Regulating Multiple Post-Transcriptional Mechanisms. J Biol Chem, In process, . (PMID: 25818199)

Munoz, J. L. Rodriguez-Cruz, V. Greco, S. J. Nagula, V. Scotto, K. W. Rameshwar, P. Temozolomide induces the production of epidermal growth factor to regulate MDR1 expression in glioblastoma cells. Mol Cancer Ther, 13:2399-2411, . (PMID: 25053824)

Xie, X. Bansal, N. Shaik, T. Kerrigan, J. E. Minko, T. Garbuzenko, O. Abali, E. E. Johnson-Farley, N. Banerjee, D. Scotto, K. W. Bertino, J. R. A novel peptide that inhibits E2F transcription and regresses prostate tumor xenografts. Oncotarget, 5:901-907, . (PMID: 24658650, PMCID: PMC4011592)

Xie, X. Kerrigan, J. E. Minko, T. Garbuzenko, O. Lee, K. C. Scarborough, A. Abali, E. E. Budak-Alpdogan, T. Johnson-Farley, N. Banerjee, D. Scotto, K. W. Bertino, J. R. Antitumor and modeling studies of a penetratin-peptide that targets E2F-1 in small cell lung cancer. Cancer Biol Ther, 14:742-751, . (PMID: 23792570)

Hsieh, Y. C. Tedeschi, P. Adebisi Lawal, R. Banerjee, D. Scotto, K. Kerrigan, J. E. Lee, K. C. Johnson-Farley, N. Bertino, J. R. Abali, E. E. Enhanced Degradation of Dihydrofolate Reductase through Inhibition of NAD Kinase by Nicotinamide Analogs. Mol Pharmacol, 83:339-353, . (PMID: 23197646, PMCID: PMC3558814)

Roussel, B. Johnson-Farley, N. Kerrigan, J. E. Scotto, K. W. Banerjee, D. Felczak, K. Pankiewicz, K. W. Gounder, M. Lin, H. Abali, E. E. Bertino, J. R. A second target of benzamide riboside: Dihydrofolate reductase. Cancer Biol Ther, 13:1290-1298, . (PMID: 22954684, PMCID: PMC3493437)

Miletti-Gonzalez, K. E. Murphy, K. Kumaran, M. N. Ravindranath, A. K. Wernyj, R. P. Kaur, S. Miles, G. D. Lim, E. Chan, R. Chekmareva, M. Heller, D. S. Foran, D. Chen, W. Reiss, M. Bandera, E. V. Scotto, K. Rodriguez-Rodriguez, L. Identification of function for CD44 intracytoplasmic domain (CD44-ICD): modulation of matrix metalloproteinase 9 (MMP-9) transcription via novel promoter response element. J Biol Chem, 287:18995-19007, . (PMID: 22433859, PMCID: PMC3365933)

Ding, R. Shi, J. Pabon, K. Scotto, K. W. Xanthines down-regulate the drug transporter ABCG2 and reverse multidrug resistance. Mol Pharmacol, 81:328-337, . (PMID: 22113078, PMCID: PMC3286305)