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Yufang Shi, DVM, MSc,PhD

Publications since 2011

Ren, G. Liu, Y. Zhao, X. Zhang, J. Zheng, B. Yuan, Z. R. Zhang, L. Qu, X. Tischfield, J. A. Shao, C. Shi, Y. Tumor resident mesenchymal stromal cells endow naive stromal cells with tumor-promoting properties. Oncogene, 33:4016-4020, . (PMID: 24077286)

Han, X. Yang, Q. Lin, L. Xu, C. Zheng, C. Chen, X. Han, Y. Li, M. Cao, W. Cao, K. Chen, Q. Xu, G. Zhang, Y. Zhang, J. Schneider, R. J. Qian, Y. Wang, Y. Brewer, G. Shi, Y. Interleukin-17 enhances immunosuppression by mesenchymal stem cells. Cell Death Differ, In process, . (PMID: 25034782)

Huang, Y. Yu, P. Li, W. Ren, G. Roberts, A. I. Cao, W. Zhang, X. Su, J. Chen, X. Chen, Q. Shou, P. Xu, C. Du, L. Lin, L. Xie, N. Zhang, L. Wang, Y. Shi, Y. p53 regulates mesenchymal stem cell-mediated tumor suppression in a tumor microenvironment through immune modulation. Oncogene, 33:3830-3838, . (PMID: 23975435)

Cao, G. Yang, Q. Zhang, S. Xu, C. Roberts, A. I. Wang, Y. Shi, Y. Mesenchymal Stem Cells Prevent Restraint Stress-Induced Lymphocyte Depletion via Interleukin-4. Brain Behav Immun, 38:125-132, . (PMID: 24480719)

Su, J. Chen, X. Huang, Y. Li, W. Li, J. Cao, K. Cao, G. Zhang, L. Li, F. Roberts, A. I. Kang, H. Yu, P. Ren, G. Ji, W. Wang, Y. Shi, Y. Phylogenetic distinction of iNOS and IDO function in mesenchymal stem cell-mediated immunosuppression in mammalian species. Cell Death Differ, 21:388-396, . (PMID: 24162664, PMCID: PMC3921585)

Ling, W. Zhang, J. Yuan, Z. Ren, G. Zhang, L. Chen, X. Rabson, A. B. Roberts, A. I. Wang, Y. Shi, Y. Mesenchymal Stem Cells Employ IDO to Regulate Immunity in Tumor Microenvironment. Cancer Res, 74:1576-1587, . (PMID: 24452999, PMCID: PMC3959857)

Chen, Q. Shou, P. Zhang, L. Xu, C. Zheng, C. Han, Y. Li, W. Huang, Y. Zhang, X. Shao, C. Roberts, A. I. Rabson, A. B. Ren, G. Zhang, Y. Wang, Y. Denhardt, D. T. Shi, Y. An Osteopontin-Integrin interaction plays a critical role in directing adipogenesis and osteogenesis by mesenchymal stem cells. Stem Cells, 32:327-337, . (PMID: 24123709, PMCID: PMC3961005)

Ma, S. Xie, N. Li, W. Yuan, B. Shi, Y. Wang, Y. Immunobiology of mesenchymal stem cells. Cell Death Differ, 21:216-225, . (PMID: 24185619, PMCID: PMC3890955)

Chen, X. Gan, Y. Li, W. Su, J. Zhang, Y. Huang, Y. Roberts, A. I. Han, Y. Li, J. Wang, Y. Shi, Y. The interaction between mesenchymal stem cells and steroids during inflammation. Cell Death Dis, 5:e1009, . (PMID: 24457953, PMCID: PMC4040685)

Zhang, J. Roberts, A. I. Liu, C. Ren, G. Xu, G. Zhang, L. Devadas, S. Shi, Y. A novel subset of helper T cells promotes immune responses by secreting GM-CSF. Cell Death Differ, 20:1731-1741, . (PMID: 24076588, PMCID: PMC3824596)

Zeng, A. Li, Y. Q. Wang, C. Han, X. S. Li, G. Wang, J. Y. Li, D. S. Qin, Y. W. Shi, Y. Brewer, G. Jing, Q. Heterochromatin protein 1 promotes self-renewal and triggers regenerative proliferation in adult stem cells. J Cell Biol, 201:409-425, . (PMID: 23629965, PMCID: PMC3639387)

Xu, C. Ren, G. Cao, G. Chen, Q. Shou, P. Zheng, C. Du, L. Han, X. Jiang, M. Yang, Q. Lin, L. Wang, G. Yu, P. Zhang, X. Cao, W. Brewer, G. Wang, Y. Shi, Y. miR-155 regulates immune modulatory properties of mesenchymal stem cells by targeting TAK1-binding protein 2. J Biol Chem, 288:11074-11079, . (PMID: 23449975, PMCID: PMC3630877)

Wu, X. Chesoni, S. Rondeau, G. Tempesta, C. Patel, R. Charles, S. Daginawala, N. Zucconi, B. E. Kishor, A. Xu, G. Shi, Y. Li, M. L. Irizarry-Barreto, P. Welsh, J. Wilson, G. M. Brewer, G. Combinatorial mRNA binding by AUF1 and Argonaute 2 controls decay of selected target mRNAs. Nucleic Acids Res, 41:2644-2658, . (PMID: 23303783, PMCID: PMC3575833)

Ren, G. Zhao, X. Wang, Y. Zhang, X. Chen, X. Xu, C. Yuan, Z. R. Roberts, A. I. Zhang, L. Zheng, B. Wen, T. Han, Y. Rabson, A. B. Tischfield, J. A. Shao, C. Shi, Y. CCR2-Dependent Recruitment of Macrophages by Tumor-Educated Mesenchymal Stromal Cells Promotes Tumor Development and Is Mimicked by TNFalpha Cell Stem Cell, 11:812-824, . (PMID: 23168163, PMCID: PMC3518598)

Qu, F. Gao, H. Zhu, S. Shi, P. Zhang, Y. Liu, Y. Jallal, B. Yao, Y. Shi, Y. Qian, Y. TRAF6-dependent Act1 phosphorylation by the IkappaB kinase-related kinases suppresses interleukin-17-induced NF-kappaB activation. Mol Cell Biol, 32:3925-3937, . (PMID: 22851696, PMCID: PMC3457531)

Li, W. Ren, G. Huang, Y. Su, J. Han, Y. Li, J. Chen, X. Cao, K. Chen, Q. Shou, P. Zhang, L. Yuan, Z. R. Roberts, A. I. Shi, S. Le, A. D. Shi, Y. Mesenchymal stem cells: a double-edged sword in regulating immune responses. Cell Death Differ, 19:1505-1513, . (PMID: 22421969, PMCID: PMC3422473)

Zhu, S. Pan, W. Song, X. Liu, Y. Shao, X. Tang, Y. Liang, D. He, D. Wang, H. Liu, W. Shi, Y. Harley, J. B. Shen, N. Qian, Y. The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-alpha. Nat Med, 18:1077-1086, . (PMID: 22660635)

Yao, Y. Wang, Y. Chen, F. Huang, Y. Zhu, S. Leng, Q. Wang, H. Shi, Y. Qian, Y. NLRC5 regulates MHC class I antigen presentation in host defense against intracellular pathogens. Cell Res, 22:836-847, . (PMID: 22491475, PMCID: PMC3346158)

Shi, Y. Su, J. Roberts, A. I. Shou, P. Rabson, A. B. Ren, G. How mesenchymal stem cells interact with tissue immune responses. Trends Immunol, 33:136-143, . (PMID: 22227317, PMCID: PMC3412175)

Shi, Y. Wei, L. Wang, Y. Ren, G. Stem cells deployed for bone repair hijacked by T cells. Cell Stem Cell, 10:6-8, . (PMID: 22226348)

Sensebe, L. Tarte, K. Galipeau, J. Krampera, M. Martin, I. Phinney, D. G. Shi, Y. Limited acquisition of chromosomal aberrations in human adult mesenchymal stromal cells. Cell Stem Cell, 10:9-10; author reply 10, . (PMID: 22226349)

Han, Z. Jing, Y. Zhang, S. Liu, Y. Shi, Y. Wei, L. The role of immunosuppression of mesenchymal stem cells in tissue repair and tumor growth. Cell Biosci, 2:8, . (PMID: 22390479, PMCID: PMC3315743)

Song, X. Zhu, S. Shi, P. Liu, Y. Shi, Y. Levin, S. D. Qian, Y. IL-17RE is the functional receptor for IL-17C and mediates mucosal immunity to infection with intestinal pathogens. Nat Immunol, 12:1151-1158, . (PMID: 21993849)

Han, Z. Tian, Z. Lv, G. Zhang, L. Jiang, G. Sun, K. Wang, C. Bu, X. Li, R. Shi, Y. Wu, M. Wei, L. Immunosuppressive effect of bone marrow-derived mesenchymal stem cells in inflammatory microenvironment favours the growth of B16 melanoma cells. J Cell Mol Med, 15:2343-2352, . (PMID: 21091630)

Cao, W. Yang, Y. Wang, Z. Liu, A. Fang, L. Wu, F. Hong, J. Shi, Y. Leung, S. Dong, C. Zhang, J. Z. Leukemia inhibitory factor inhibits T helper 17 cell differentiation and confers treatment effects of neural progenitor cell therapy in autoimmune disease. Immunity, 35:273-284, . (PMID: 21835648)

Krause, C. D. Izotova, L. S. Ren, G. Yuan, Z. R. Shi, Y. Chen, C. C. Ron, Y. Pestka, S. Efficient co-expression of bicistronic proteins in mesenchymal stem cells by development and optimization of a multifunctional plasmid. Stem Cell Res Ther, In process, . (PMID: 21401924)

Zhao, F. Zhang, Y. Wang, H. Jin, M. He, S. Shi, Y. Guo, Y. Zhang, Y. Blockade of osteopontin reduces alloreactive CD8+ T cell-mediated graft-versus-host disease. Blood, 117:1723-1733, . (PMID: 21119110, PMCID: PMC3056597)

Ren, G. Roberts, A. I. Shi, Y. Adhesion molecules: key players in Mesenchymal stem cell-mediated immunosuppression. Cell Adh Migr, 5:20-22, . (PMID: 20935502, PMCID: PMC3038091)

Shi, P. Zhu, S. Lin, Y. Liu, Y. Liu, Y. Chen, Z. Shi, Y. Qian, Y. Persistent stimulation with interleukin-17 desensitizes cells through SCFbeta-TrCP-mediated degradation of Act1. Sci Signal, 4:ra73, . (PMID: 22045853)