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Gary A. Brewer, PhD

Publications since 2011

Weng, K. F. Hung, C. T. Hsieh, P. T. Li, M. L. Chen, G. W. Kung, Y. A. Huang, P. N. Kuo, R. L. Chen, L. L. Lin, J. Y. Wang, R. Y. Chen, S. J. Tang, P. Horng, J. T. Huang, H. I. Wang, J. R. Ojcius, D. M. Brewer, G. Shih, S. R. A cytoplasmic RNA virus generates functional viral small RNAs and regulates viral IRES activity in mammalian cells. Nucleic Acids Res, 42:12789-12805, . (PMID: 25352551, PMCID: PMC4227785)

Han, X. Yang, Q. Lin, L. Xu, C. Zheng, C. Chen, X. Han, Y. Li, M. Cao, W. Cao, K. Chen, Q. Xu, G. Zhang, Y. Zhang, J. Schneider, R. J. Qian, Y. Wang, Y. Brewer, G. Shi, Y. Interleukin-17 enhances immunosuppression by mesenchymal stem cells. Cell Death Differ, 21:1758-1768, . (PMID: 25034782, PMCID: PMC4211372)

Lin, J. Y. Li, M. L. Brewer, G. mRNA Decay Factor AUF1 Binds the Internal Ribosomal Entry Site of Enterovirus 71 and Inhibits Virus Replication. PLoS One, 9:e103827, . (PMID: 25077793, PMCID: PMC4117571)

White, E. J. Brewer, G. Wilson, G. M. Post-transcriptional control of gene expression by AUF1: Mechanisms, physiological targets, and regulation. Biochim Biophys Acta, 1829:680-688, . (PMID: 23246978, PMCID: PMC3664190)

Li, M. L. Defren, J. Brewer, G. Hsp27 and F-box protein beta-TrCP promote degradation of mRNA decay factor AUF1. Mol Cell Biol, 33:2315-2326, . (PMID: 23530064, PMCID: PMC3648078)

Zeng, A. Li, Y. Q. Wang, C. Han, X. S. Li, G. Wang, J. Y. Li, D. S. Qin, Y. W. Shi, Y. Brewer, G. Jing, Q. Heterochromatin protein 1 promotes self-renewal and triggers regenerative proliferation in adult stem cells. J Cell Biol, 201:409-425, . (PMID: 23629965, PMCID: PMC3639387)

Xu, C. Ren, G. Cao, G. Chen, Q. Shou, P. Zheng, C. Du, L. Han, X. Jiang, M. Yang, Q. Lin, L. Wang, G. Yu, P. Zhang, X. Cao, W. Brewer, G. Wang, Y. Shi, Y. miR-155 regulates immune modulatory properties of mesenchymal stem cells by targeting TAK1-binding protein 2. J Biol Chem, 288:11074-11079, . (PMID: 23449975, PMCID: PMC3630877)

Wu, X. Chesoni, S. Rondeau, G. Tempesta, C. Patel, R. Charles, S. Daginawala, N. Zucconi, B. E. Kishor, A. Xu, G. Shi, Y. Li, M. L. Irizarry-Barreto, P. Welsh, J. Wilson, G. M. Brewer, G. Combinatorial mRNA binding by AUF1 and Argonaute 2 controls decay of selected target mRNAs. Nucleic Acids Res, 41:2644-2658, . (PMID: 23303783, PMCID: PMC3575833)

Kishor, A. Tandukar, B. Ly, Y. V. Toth, E. A. Suarez, Y. Brewer, G. Wilson, G. M. Hsp70 is a novel posttranscriptional regulator of gene expression that binds and stabilizes selected mRNAs containing AU-rich elements. Mol Cell Biol, 33:71-84, . (PMID: 23109422, PMCID: PMC3536313)

Mou, Z. You, J. Xiao, Q. Wei, Y. Yuan, J. Liu, Y. Brewer, G. Ma, W. J. HuR posttranscriptionally regulates early growth response-1 (Egr-1) expression at the early stage of T cell activation. FEBS Lett, 586:4319-4325, . (PMID: 23127556)

Wu, X. Brewer, G. The regulation of mRNA stability in mammalian cells: 2.0. Gene, 500:10-21, . (PMID: 22452843, PMCID: PMC3340483)

Qi, M. Y. Wang, Z. Z. Zhang, Z. Shao, Q. Zeng, A. Li, X. Q. Li, W. Q. Wang, C. Tian, F. J. Li, Q. Zou, J. Qin, Y. W. Brewer, G. Huang, S. Jing, Q. AU-rich-element-dependent translation repression requires the cooperation of tristetraprolin and RCK/P54. Mol Cell Biol, 32:913-928, . (PMID: 22203041, PMCID: PMC3295194)

Xin, H. Brown, J. A. Gong, C. Fan, H. Brewer, G. Gnarra, J. R. Association of the von Hippel-Lindau protein with AUF1 and posttranscriptional regulation of VEGFA mRNA. Mol Cancer Res, 10:108-120, . (PMID: 22086907, PMCID: PMC3262120)

Liao, B. Hu, Y. Brewer, G. RNA-binding protein insulin-like growth factor mRNA-binding protein 3 (IMP-3) promotes cell survival via insulin-like growth factor II signaling after ionizing radiation. J Biol Chem, 286:31145-31152, . (PMID: 21757716, PMCID: PMC3173139)

Knapinska, A. M. Gratacos, F. M. Krause, C. D. Hernandez, K. Jensen, A. G. Bradley, J. J. Wu, X. Pestka, S. Brewer, G. Chaperone Hsp27 modulates AUF1 proteolysis and AU-rich element-mediated mRNA degradation. Mol Cell Biol, 31:1419-1431, . (PMID: 21245386, PMCID: PMC3135302)

Sarkar, S. Han, J. Sinsimer, K. S. Liao, B. Foster, R. L. Brewer, G. Pestka, S. RNA-binding protein AUF1 regulates lipopolysaccharide-induced IL10 expression by activating IkappaB kinase complex in monocytes. Mol Cell Biol, 31:602-615, . (PMID: 21135123, PMCID: PMC3028643)