Physician Profile

Malcolm Mattes, MD
Radiation Oncologist

I am a radiation oncologist who specializes in the treatment of gynecologic, genitourinary, lung, breast, and musculoskeletal tumors. Radiation therapy is an important treatment modality to be able to offer patients, because when used effectively it can either cure a cancer while preserving quality-of-life in ways that surgery often cannot, or alleviate symptoms with minimal side effects.

I believe strongly in patient-centered care, in which patients are partners with their health care providers. I try hard to communicate treatment options openly and honestly with my patients so that they can not only make the best decision to treat their cancer, but also make the best decision for them as a person.  It is a privilege to be able to help people through a difficult time in their lives, and I take pride in being a strong advocate for my patients’ well-being.

In addition to my clinical work, I enjoy teaching medical students and residents about radiation oncology, and effective multidisciplinary cancer care. I have mentored numerous students in a variety of research projects, and have led several clinical trials related to immuno-oncology, tumor metabolism, and personalized medicine.

Current Service/Volunteer Committees:

  • Member, ASTRO Communications Committee
  • Member, ASTRO Workforce Subcommittee
  • Member, ASTRO Education Committee
  • Member, ASTRO Committee on Health Equity, Diversity, and Inclusion
  • Co-Chair, Education Subcommittee, ASTRO Committee on Health Equity, Diversity, and Inclusion
  • Member, NRG Oncology Gastrointestinal Cancer Committee (Colorectal and Non-Colorectal)
  • Member, NRG Oncology Genitourinary Cancer Committee
  • Member, ABR Thoracic Cancer/Sarcoma Clinical Category Committee
Clinical Expertise 

Gynecologic oncology, genitourinary cancers, lung cancer, breast cancer and musculoskeletal tumors

Grants and Awards 

Jul 2019–Jun 2021, WVCTSI/WVUCI Pilot Grant: Development of a Novel Radioprotective Therapeutic for the Small Intestines 

Jan 2019–Jun 2019, West Virginia IDeA-CTR Pilot Grant: Measurement of Tumor Oxygenation Using Electron Paramagnetic Resonance

Jul 2018–Jul 2019, WVUCI/American Cancer Society IRG Pilot Project Grant: Methionine-Restricted Diet to Potentiate The Effects of Radiation Therapy

Jul 2016–Jun 2018, West Virginia IDeA-CTR Research Scholar Award: Use of Response-Adapted Hypofractionated Radiation Therapy to Potentiate the Systemic Immune Response to Checkpoint Inhibitors in Non-Small Cell Lung Cancer


2014                       Radiosurgery Course Scholarship/Participant, AANS/ASTRO

2015                       High Dose Rate Brachytherapy Scholarship/Participant, American Brachytherapy Society (ABS)

2016                       Award for Innovation, WVU Cancer Institute

2016                       Research Scholar Award, West Virginia Clinical and Translational Science Institute (WVCTSI)

2017                       Inducted, Academy of Excellence in Teaching and Learning, WVU School of Medicine

Contact Information  

For appointments at Rutgers Cancer Institute of New Jersey at University Hospital, please call 973-972-5108.

To schedule a new patient appointment in New Brunswick call 732-235-8515.

For all other inquiries call 732-235-2465.

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