Researcher Profile

Suzie Chen, PhD

Professor of Chemical Biology
Ernest Mario School of Pharmacy
Rutgers, The State University of New Jersey

Susan L. Cullman Laboratory for Cancer Research
164 Frelinghuysen Road, Room 204
Piscataway, NJ 08854-8020

Phone: (732) 445-3400
Email: suziec@pharmacy.rutgers.edu

Assistant: Erica DiPaola
(732) 445-3400
Email: edipaola@pharmacy.rutgers.edu

Research Program Alignment

Membership Type: Full


Research Interests

  • Molecular mechanisms of melanoma development using a line of transgenic mice (TG-3).

Selected Publications

Creagan, R., Tischfield, J., McMorris, F.A., Chen, S., Hirschi, M., Chen, T.R., Ricciuti, F., and Ruddle, F.H.  Assignments of the genes for human peptidase A to Chromosome 18 and cytoplasmic glutamic oxaloacetate transaminase to chromosome 10 using somatic cell hybrids.  Cytogenet. Cell Genet. 12: 187-198, 1973.

Creagan, R.P., Tan, Y.H., Chen, S., Tischfield, J.A., and Ruddle, F.H. Mouse-human somatic cell hybrids utilizing human parental cells containing a 14/22 translocation: assignment of the gene for nucleoside phosphorylase to chromosome 14.  In:  New Haven Conference (1973):  First International Workshop on Human Gene Mapping, Birth Defects: Original Articles Series, X, 1974.  The National Foundation, New York, D. Bersma, ed. (Also in Cytogenet Cell Genet. 13: 83-85, 1974).

Creagan, R.P., Carrit, B., Chen, S., Kucherlapati, R., Ricciuti, F., Tan, Y.H., Tischfield, J.A., and Ruddle, F.H.  Confirmation of the synteny of the human genes for cytoplasmic isocitrate dehydrogenase and cytoplasmic malate dehydrogenase and assignment to chromosome 2.  In: New Haven Conference (1973) (also Cytogenet. Cell Genet. 13: 79-82, 1974).

Creagan, R.P., Carrit, B., Chen, S., Kucherlapati, R., McMorris, F.A., Ricciuti, F., Tan, Y.H., Tischfield, J.A., and Ruddle, F.H.  Chromosome assignments of genes in man using mouse-human somatic cell hybrids: cytoplasmic isocitrate dehydrogenase and malate dehydrogenase to chromosome 2. Am. J. Hum. Genet. 26: 604-613, 1974.

Creagan, R.P., Tan, T.H., Chen, S., and Ruddle, F.H.  Somatic cell genetic analysis of the interferon system.  Fed. Prod. 34: 2222-2226, 1975.

Creagan, R.P., Chen, S., and Ruddle, F.H.  Chromosome assignments in man using mouse-human somatic cell hybrids: association of diptheria toxin sensitivity with chromosome 5.  In: Rotterdam Conference (1974): Second International Workshop on Human Gene Mapping, Birth Defects: Original Article Series XI, 1975.

Creagan, R.P., Chen, S., and Ruddle, F.H. Genetic analysis of the cell surface: association of human chromosome 5 with sensitivity to diptheria toxin of mouse-human somatic cell hybrids.  Proc. Natl. Acad. Sci., USA 72: 2237-2241, 1975.

Murnane, M.J., Kucherlapati, R.S., Chen, S., and Ruddle, F.H.  Assignment of a genetic element for human B-glucuronidase to chromosome 9.  Am. J. Hum. Gen. 27: 68A, 1975.

Chen, S., McDougall, J.K., Creagan, R.P., Lewis, V., and Ruddle, F.H. Genetic homology between man and the chimpanzee: syntenic relationships of genes for galactokinase and thymidine kinase and adenovirus-12 induced gaps using chimpanzee-mouse somatic cell hybrids.  Somatic Cell Genetics 2: 205-213, 1976.

Chen, S. McDougall, J.K., Creagan, R.P., Lewis, V., and Ruddle, F.H. Mapping of genes and adenovirus-12 induced gaps using chimpanzee-mouse somatic cell hybrids.  In:  Human Gene Mapping III., Baltimore Conference: Original Article Series XII 412-415, 1976.

Friend, K.K., Chen, S., and Ruddle, F.H. Differential staining of interspecific chromosomes in somatic cell hybrids by alkaline giesma stain. Somatic Cell Genetics 2: 183-188, 1976.

Bubbers, J.E., Chen, S., and Lilly, F.  Non-random inclusion of H-2K and H-2D antigens in Friend virus particles from mice of various strains. J. Exp. Med. 147: 340-351, 1978.

Chen, S., and Lilly, F.  Detection of H2-Db antigen on osmotic shock-treated Friend leukemia virus particles. Immunogenetics 9: 25-31, 1979.

Chen, S., and Lilly, F.  Genetic control of MuLV expression and spontaneous lymphoma in crosses of high- and low-lymphoma strains.  (In:  Animal Virus Genetics B. Fields, R. Jaenisch and C.F. Fox, Eds.) Academic Press, New York, 207-215,1980.

Chen, S., Duran-Struuk, F., Duran-Reynals, M., and Lilly, F.  Genetic and nongenetic factors in expression of infectious murine leukemia viruses in mice of the DBA/2 x RF cross.  Cell 21: 849-855, 1980.

The content for this Research Profile is maintained by Paul Novembre (novembre@cinj.rutgers.edu)