Hilary A. Coller, PhD Assistant Professor of Molecular Biology Princeton University 140 Lewis Thomas Laboratory Washington Road Princeton, NJ 08544 Phone: (609) 258-8466 Email: hcoller@princeton.edu Assistant: Leland Burnham (609) 258-1694 Email: lburnham@princeton.edu

Research Program Alignment

• Cell Death and Survival Signaling Program

Membership Type: Full

Selected Publications

Coller, H.A.*, Sang, L.* and Roberts, J.M. (2006) A new description of cellular quiescence. PLoS Biol. 4: e83 (Selected for Faculty of 1000). PMCID: PMC1393757. 

Huttenhower, C., Flamholz, A., Landis, J., Sahi, S., Myers, C., Olczewski K., Hibbs, M., Siemers, N., Troyanskaya, O. and Coller, H.A. (2007) Nearest Neighbor Networks: Clustering expression data based on gene neighborhoods, BMC Bioinformatics, 8(1): 250. PMCID:PMC1941745

Munger, J., Bajad, S.U., Coller, H.A., Shenk, T. and Rabinowitz, J.D. (2006) Dynamics of the cellular metabolome during HCMV infection, PLoS Pathogens, 2(12): e132.

Goodpaster, T., Legesse-Miller, A., Hameed, M., Aisner, S., Randolph-Habecker, J. and Coller, H.A. (2008) An immunohistochemical method for identifying fibroblasts, Journal of Histochemistry and Cytochemistry, 56(4): 347-358. PMCID:PMC2326106

Pollina, E., Legesse-Miller, A., Haley, E., Goodpaster, T., Randolph-Habecker, J. and Coller, H.A. (2008) Regulating the angiogenic balance in tissues: A potential role for the proliferative state of fibroblasts, Cell Cycle, 7(13): 2056-2070. PMCID: PMC3121332

Forman, J.J., Legesse-Miller, A. and Coller, H.A. (2008) A search for highly conserved sequences in coding regions finds that let-7 targets Dicer within its coding sequence, Proc. Natl. Acad. Sci. USA, 105(39): 14879-14884. PMCID:  PMC2567461

Sang, L., Coller, H.A., and Roberts, J.M. (2008) HES1 regulates the reversibility of cellular quiescence, Science, 321(5892): 1095-1100 (Selected for Faculty of 1000). PMCID: PMC2721335

Huttenhower, C.*, Haley, E.M.*, Hibbs, M.A., Dumeaux, V., Coller, H.A.* and Troyanskaya, O.G.* (2009) A functional map of the human genome, Genome Research, 9(6):1093-106. PMCID: PMC2694471

Legesse-Miller, A., Elemento, O., Pfau, S., Forman, J.J., Tavazoie, S. and Coller, H.A. (2009) let-7 overexpression leads to G2/M arrest, direct down-regulation of Cdc34 and stabilization of Wee1 kinase in primary fibroblasts, Journal of Biological Chemistry, 284(11): 6605-6609.  PMCID: PMC2652271

Wellen, K.E., Lu, C., Mancuso, A., Lemons, J.M., Ryczko, M., Dennis, J.W., Rabinowitz, J.D., Coller, H.A. and Thompson, C.B. (2010) The hexosamine biosynthetic pathway coordinates glucose and glutamine metabolism through regulation of IL-3Ra, Genes and Development, 24(24) 2784-2799 (Selected for Faculty of 1000).  PMCID: PMC3003197

Lemons, J.M.L., Feng, X.-J., Bennett, B.D., Legesse-Miller, A., Johnson, E.L., Raitman, I., Pollina, E.A., Rabitz, H.A., Rabinowitz, J.D. and Coller, H.A. (2010) Quiescent fibroblasts exhibit active metabolism, PloS Biology, 8(10): e1000514. (Selected for Nature Research Highlights, Faculty of 1000). PMCID: PMC2958657

Guo, J.Y., Chen, H.-Y., Mathew, R., Fan, J., Strohecker, A.M., Kamphorst, J.J., Chen, G., Lemons, J.M.S., Karantza, V., Coller, H.A., DiPaola, R.S.,  Gelinas, C., Rabinowitz, J.D. and White, E. (2011) Activated ras requires autophagy to maintain oxidative metabolism and tumorigenesis, Genes and Development, 25(25): 460-470. (Selected for Faculty of 1000). PMCID: PMC3049287

Coller, H.A. (2011) The essence of quiescence, Science 334: 1074-1075. PMID:22116874; in process

Wang, D.J, Legesse-Miller, A., Johnson, E.L., and Coller, H.A. (2012) Regulation of the let-7a-3 promoter by NF-kB, PloS One, 7(2): e31240. PMCID:PMC3278432

Legesse-Miller, A., Raitman, I., Haley, E.M., Liao, A., Sun, L., Wang, D.J., Suh, E.J., Johnson, E.L., Lund, B., and Coller, H.A. (2012) Quiescent fibroblasts are protected from proteasome inhibition-mediated toxicity.  Molecular Biology of the Cell, 23: 3567-3581.