Researcher Profiles

Return to member profile

Neerja Kaushik-Basu, PhD

Publications since 2011

Lopez-Jimenez, A. J. Clemente-Casares, P. Sabariegos, R. Llanos-Valero, M. Bellon-Echeverria, I. Encinar, J. A. Kaushik-Basu, N. Froeyen, M. Mas, A. Hepatitis C virus polymerase-polymerase contact interface: Significance for virus replication and antiviral design. Antiviral Res, 108:14-24, . (PMID: 24815023)

Patel, B. A. Krishnan, R. Khadtare, N. Gurukumar, K. R. Basu, A. Arora, P. Bhatt, A. Patel, M. R. Dana, D. Kumar, S. Kaushik-Basu, N. Talele, T. T. Design and synthesis of L- and D-phenylalanine derived rhodanines with novel C5-arylidenes as inhibitors of HCV NS5B polymerase. Bioorg Med Chem, 21:3262-3271, . (PMID: 23598249, PMCID: PMC3651775)

Nichols, D. B. Leao, R. A. Basu, A. Chudayeu, M. de Moraes Pde, F. Talele, T. T. Costa, P. R. Kaushik-Basu, N. Evaluation of coumarin and neoflavone derivatives as HCV NS5B polymerase inhibitors. Chem Biol Drug Des, 81:607-614, . (PMID: 23311976)

Barreca, M. L. Manfroni, G. Leyssen, P. Winquist, J. Kaushik-Basu, N. Paeshuyse, J. Krishnan, R. Iraci, N. Sabatini, S. Tabarrini, O. Basu, A. Danielson, U. H. Neyts, J. Cecchetti, V. Structure-based discovery of pyrazolobenzothiazine derivatives as inhibitors of hepatitis C virus replication. J Med Chem, 56:2270-2282, . (PMID: 23409936, PMCID: PMC3627225)

Kucukguzel, S. G. Coskun, I. Aydin, S. Aktay, G. Gursoy, S. Cevik, O. Ozakpinar, O. B. Ozsavci, D. Sener, A. Kaushik-Basu, N. Basu, A. Talele, T. T. Synthesis and characterization of celecoxib derivatives as possible anti-inflammatory, analgesic, antioxidant, anticancer and anti-HCV agents. Molecules, 18:3595-3614, . (PMID: 23519201)

Patil, V. M. R, G. K. Chudayeu, M. Gupta, S. P. Samanta, S. Masand, N. Kaushik-Basu, N. Synthesis, in vitro and in silico NS5B polymerase inhibitory activity of benzimidazole derivatives. Med Chem, 8:629-635, . (PMID: 22530910)

Nichols, D. B. Fournet, G. Gurukumar, K. R. Basu, A. Lee, J. C. Sakamoto, N. Kozielski, F. Musmuca, I. Joseph, B. Ragno, R. Kaushik-Basu, N. Inhibition of hepatitis C virus NS5B polymerase by S-trityl-L-cysteine derivatives. Eur J Med Chem, 49:191-199, . (PMID: 22280819, PMCID: PMC3288800)

Bhatt, A. Gurukumar, K. R. Basu, A. Patel, M. R. Kaushik-Basu, N. Talele, T. T. Synthesis and SAR optimization of diketo acid pharmacophore for HCV NS5B polymerase inhibition. Eur J Med Chem, 46:5138-5145, . (PMID: 21893371, PMCID: PMC3208381)

Pandey, N. Mishra, C. A. Manvar, D. Upadhyay, A. K. Talele, T. T. Comollo, T. W. Kaushik-Basu, N. Pandey, V. N. The glutamine side chain at position 91 on the beta5a-beta5b loop of human immunodeficiency virus type 1 reverse transcriptase is required for stabilizing the dNTP binding pocket. Biochemistry, 50:8067-8077, . (PMID: 21800837, PMCID: PMC3204787)