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Neerja Kaushik-Basu, PhD

Publications since 2011

Manvar, D. Pelliccia, S. La Regina, G. Famiglini, V. Coluccia, A. Ruggieri, A. Anticoli, S. Lee, J. C. Basu, A. Cevik, O. Nencioni, L. Palamara, A. T. Zamperini, C. Botta, M. Neyts, J. Leyssen, P. Kaushik-Basu, N. Silvestri, R. New 1-phenyl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides inhibit hepatitis C virus replication via suppression of cyclooxygenase-2. Eur J Med Chem, In process, . (PMID: 25483263)

Lopez-Jimenez, A. J. Clemente-Casares, P. Sabariegos, R. Llanos-Valero, M. Bellon-Echeverria, I. Encinar, J. A. Kaushik-Basu, N. Froeyen, M. Mas, A. Hepatitis C virus polymerase-polymerase contact interface: Significance for virus replication and antiviral design. Antiviral Res, 108:14-24, . (PMID: 24815023)

Patel, B. A. Krishnan, R. Khadtare, N. Gurukumar, K. R. Basu, A. Arora, P. Bhatt, A. Patel, M. R. Dana, D. Kumar, S. Kaushik-Basu, N. Talele, T. T. Design and synthesis of L- and D-phenylalanine derived rhodanines with novel C5-arylidenes as inhibitors of HCV NS5B polymerase. Bioorg Med Chem, 21:3262-3271, . (PMID: 23598249, PMCID: PMC3651775)

Nichols, D. B. Leao, R. A. Basu, A. Chudayeu, M. de Moraes Pde, F. Talele, T. T. Costa, P. R. Kaushik-Basu, N. Evaluation of coumarin and neoflavone derivatives as HCV NS5B polymerase inhibitors. Chem Biol Drug Des, 81:607-614, . (PMID: 23311976)

Barreca, M. L. Manfroni, G. Leyssen, P. Winquist, J. Kaushik-Basu, N. Paeshuyse, J. Krishnan, R. Iraci, N. Sabatini, S. Tabarrini, O. Basu, A. Danielson, U. H. Neyts, J. Cecchetti, V. Structure-based discovery of pyrazolobenzothiazine derivatives as inhibitors of hepatitis C virus replication. J Med Chem, 56:2270-2282, . (PMID: 23409936, PMCID: PMC3627225)

Kucukguzel, S. G. Coskun, I. Aydin, S. Aktay, G. Gursoy, S. Cevik, O. Ozakpinar, O. B. Ozsavci, D. Sener, A. Kaushik-Basu, N. Basu, A. Talele, T. T. Synthesis and characterization of celecoxib derivatives as possible anti-inflammatory, analgesic, antioxidant, anticancer and anti-HCV agents. Molecules, 18:3595-3614, . (PMID: 23519201)

Patil, V. M. R, G. K. Chudayeu, M. Gupta, S. P. Samanta, S. Masand, N. Kaushik-Basu, N. Synthesis, in vitro and in silico NS5B polymerase inhibitory activity of benzimidazole derivatives. Med Chem, 8:629-635, . (PMID: 22530910)

Nichols, D. B. Fournet, G. Gurukumar, K. R. Basu, A. Lee, J. C. Sakamoto, N. Kozielski, F. Musmuca, I. Joseph, B. Ragno, R. Kaushik-Basu, N. Inhibition of hepatitis C virus NS5B polymerase by S-trityl-L-cysteine derivatives. Eur J Med Chem, 49:191-199, . (PMID: 22280819, PMCID: PMC3288800)

Bhatt, A. Gurukumar, K. R. Basu, A. Patel, M. R. Kaushik-Basu, N. Talele, T. T. Synthesis and SAR optimization of diketo acid pharmacophore for HCV NS5B polymerase inhibition. Eur J Med Chem, 46:5138-5145, . (PMID: 21893371, PMCID: PMC3208381)

Pandey, N. Mishra, C. A. Manvar, D. Upadhyay, A. K. Talele, T. T. Comollo, T. W. Kaushik-Basu, N. Pandey, V. N. The glutamine side chain at position 91 on the beta5a-beta5b loop of human immunodeficiency virus type 1 reverse transcriptase is required for stabilizing the dNTP binding pocket. Biochemistry, 50:8067-8077, . (PMID: 21800837, PMCID: PMC3204787)