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George P. Studzinski, MD, PhD

Publications since 2011

Wang, X. Pesakhov, S. Harrison, J. S. Danilenko, M. Studzinski, G. P. ERK5 Pathway Regulates Transcription Factors Important for Monocytic Differentiation of Human Myeloid Leukemia Cells. J Cell Physiol, 229:856-867, . (PMID: 24264602)

Wang, X. Pesakhov, S. Weng, A. Kafka, M. Gocek, E. Nguyen, M. Harrison, J. S. Danilenko, M. Studzinski, G. P. ERK 5/MAPK PATHWAY HAS A MAJOR ROLE IN 1alpha,25-(OH) VITAMIN D-INDUCED TERMINAL DIFFERENTIATION OF MYELOID LEUKEMIA CELLS. J Steroid Biochem Mol Biol, In process, . (PMID: 24514755, PMCID: PMC4000286)

Chen-Deutsch, X. Kutner, A. Harrison, J. S. Studzinski, G. P. The pan-caspase inhibitor Q-VD-OPh has anti-leukemia effects and can interact with vitamin D analogs to increase HPK1 signaling in AML cells. Leuk Res, 36:884-888, . (PMID: 22541691, PMCID: PMC3361643)

Gocek, E. Studzinski, G. P. Genes encoding transcription factors have self-control: how important is this for cell differentiation? Leuk Res, 36:672-674, . (PMID: 22424711)

Halicka, H. D. Zhao, H. Li, J. Traganos, F. Studzinski, G. P. Darzynkiewicz, Z. Attenuation of constitutive DNA damage signaling by 1,25-dihydroxyvitamin D3. Aging (Albany NY), 4:270-278, . (PMID: 22498490, PMCID: PMC3371762)

Chen-Deutsch, X. Studzinski, G. P. Dual role of hematopoietic progenitor kinase 1 (HPK1) as a positive regulator of 1alpha,25-dihydroxyvitamin D-induced differentiation and cell cycle arrest of AML cells and as a mediator of vitamin D resistance. Cell Cycle, 11:1364-1373, . (PMID: 22421156, PMCID: PMC3350877)

Studzinski, G. P. Brown, G. Danilenko, M. Hughes, P. Marcinkowska, E. Differentiation and cell survival of myeloid leukemia cells. Leuk Res Treatment, 2012:370375, . (PMID: 23259065, PMCID: PMC3504243)

Gocek, E. Wang, X. Liu, X. Liu, C. G. Studzinski, G. P. MicroRNA-32 upregulation by 1,25-dihydroxyvitamin D3 in human myeloid leukemia cells leads to Bim targeting and inhibition of AraC-induced apoptosis. Cancer Res, 71:6230-6239, . (PMID: 21816906)

Wang, X. Studzinski, G. P. Oncoprotein Cot1 represses kinase suppressors of Ras1/2 and 1,25-dihydroxyvitamin D3-induced differentiation of human acute myeloid leukemia cells. J Cell Physiol, 226:1232-1240, . (PMID: 20945381, PMCID: PMC3440184)

Bobilev, I. Novik, V. Levi, I. Shpilberg, O. Levy, J. Sharoni, Y. Studzinski, G. P. Danilenko, M. The Nrf2 transcription factor is a positive regulator of myeloid Differentiation of acute myeloid leukemia cells. Cancer Biol Ther, 11:317-329, . (PMID: 21099366, PMCID: PMC3047086)

Zhang, J. Harrison, J. S. Studzinski, G. P. Isoforms of p38MAPK gamma and delta contribute to differentiation of human AML cells induced by 1,25-dihydroxyvitamin D(3). Exp Cell Res, 317:117-130, . (PMID: 20804750, PMCID: PMC2998239)