Researcher Profile

Derek B. Sant'Angelo, PhD

Full Member, Cancer Metabolism and Growth Program

Member since 2012

Academic Appointment

Harold L. Paz, MD Endowed Professor of Developmental Biology and Professor of Pediatrics and Pharmacology
Robert Wood Johnson Medical School
Rutgers, The State University of New Jersey


Resident Scientist and Associate Director of Basic Science, Child Health Institute of NJ; Chief, Division of Child Health Sciences


Research Interests

  • The role of the transcription factor PLZF (promyelocytic leukemia zinc-finger) in the development of lymphocyte effector functions
  • Enhancement of tumor specific T cell function by ectopic expression of PLZF
  • Transcriptional control of regulatory T cell functions
  • Control of obesity and regulation of metabolism by NKT cells and Tregs

Selected Publications

The content for this Researcher Profile is maintained by Paul Novembre (


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