Tissue Analytic Services Shared Resource

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Immunohistochemistry Service

The overall goal of the shared resource is to provide high quality, cost effective immunohistochemical technology for CINJ members.

Specific objectives include:

1. provide immunohistochemical localization of cells and antigens using well-characterized antibodies in normal and malignant tissues;
2. define the optimal conditions for novel, investigator-developed antibodies to successfully localize tissue antigens;
3. procure pure cells from specific microscopic regions of tissue sections using microdissection;
4. assist investigators with fluorescent in situ hybridization (FISH) and ISH;
5. construct TMA blocks for investigator-initiated translational research studies;
6. provide TMA sections containing large numbers of normal and malignant tissue cores; and
7. provide digital high-power imaging and archiving of stained slides, and access to the images using distributed (virtual) microscopy.