CINJ • Oncolyte • Spring 2010 Page 1

xpanding its research
horizons in the fight
against cancer, The

Cancer Institute of New Jersey
(CINJ) has formally welcomed
Princeton University as a sci-
entific collaborator, which will
allow for the sharing of
resources and the strengthen-
ing of outstanding research
programs at both institutions.

CINJ, which is

New Jersey's only
National Cancer
Institute (NCI)-
designated
Comprehensive
Cancer Center,
operates under a
"consortium cancer
center" matrix,
allowing for
formal scientific
and academic
collaboration
between CINJ and other
entities. Rutgers, The State
University of New Jersey, has
historically been a part of this
relationship since CINJ first
opened in 1993, allowing for
Rutgers scientists to work
alongside CINJ's physician-

scientists in the laboratory
and provide an outlet to bring
discoveries directly to patients.
The latest partnership with
Princeton University allows for
the same.

Many Princeton researchers

from wide-ranging disciplines,
including physics, genomics,

chemical engineering and
computer science, are engaged
in cutting-edge projects to
expand the fundamental under-
standing of cancer and develop
new therapeutic models and
treatment methods. These
efforts are housed within
numerous departments,

institutes and centers, including
the Lewis-Sigler Institute for
Integrative Genomics and the
Princeton Physical Sciences-
Oncology Center, which was
recently established with a
$15.2 million grant from the
NCI to explore how cancer

-- Continued on page 6

A Publication of The Cancer Institute of New Jersey

Spring 2010

CINJ Welcomes Princeton University as a Scientific Collaborator

Research Team Targets
Self-Cannibalizing Cancer Cells

team of scientists from

Princeton University

and The Cancer

Institute of New Jersey has
embarked on a major new
project to unravel the secret
lives of cancer cells that go
dormant and self-cannibalize

to survive periods of stress.
The work may help produce
new cancer therapies to stem
changes that render cancer
cells dangerous and resistant to
treatment.

"We want to know: What

role is this self-cannibalization
playing in the middle of a
tumor?" said team member
Hilary Coller, PhD, an assis-
tant professor of molecular
biology at Princeton. "To treat

cancer, it may be that you
want to get rid of this ability
in tumor cells, so we're search-
ing for inducers and inhibitors
of this process."

CINJ Associate Director for

Basic Science,

Eileen White,

PhD

, adjunct professor of

surgery at UMDNJ-Robert
Wood Johnson Medical
School, and professor of
molecular biology and
biochemistry at Rutgers, The
State University of New Jersey;
Dr. Coller; and Princeton

-- Continued on page 6

From left: Princeton scientists Drs.
Hilary Coller and Joshua Rabinowitz
with CINJ's Dr. Eileen White.

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