Significance of Single Nucleotide Polymorphisms in Breast Cancer Patients Undergoing Radiation Therapy

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Significance of Single Nucleotide Polymorphisms in Breast Cancer Patients Undergoing Radiation Therapy

In a cohort of approximately 250 women, diagnosed with breast cancer and treated with breast conserving surgery or mastectomy and radiation we will evaluate the frequency of this polymorphism (SNP309). We will correlate the polymorphism status with other clinical, pathologic and genetic information we have on these 250 women, including but not limited to stage, age of onset of disease, receptor status, her2 status, and the status of BRCA1 and BRCA2. We will recruit additional patients with a new diagnosis of breast cancer to correlate the status of SNP309 with other clinical and pathological variables.

Protocol Number040703
Principal InvestigatorBruce Haffty
ScopeLocal
Applicable Disease SitesBreast - Female
Participating InstitutionsRutgers Cancer Institute of New Jersey
Saint Peters University Hospital

For further information on this clinical trial, please contact us at 732-235-8675 or cinjclinicaltrials@umdnj.edu.